New research published in Experimental Neurology provides some initial evidence that the psychedelic substance known as LSD has nootropic properties. The study found that LSD increased markers of neuroplasticity in human brain organoids, increased novelty…

People who have undergone a mystical experience after consuming a psychedelic substance are more likely to engage in behaviors aimed at protecting or conserving the environment, according to new research published in the Journal of Humanistic Psychology.…

Prescribing psychedelic therapies including MDMA and psilocybin in combination with counseling and psychotherapy improve symptoms for those with PTSD.

BMC Medicine - Medical cannabinoids differ in their pharmacology and may have different treatment effects. We aimed to conduct a pharmacology-based systematic review (SR) and meta-analyses of...

Both psychedelic drug experiences and near-death experiences can occasion changes in perspectives on death and dying, but there have been few direct comparisons of these phenomena. This study directly compared psychedelic occasioned and non-drug experiences…

This study aimed to investigate the efficacy and safety of lysergic acid diethylamide
(LSD)–assisted therapy in patients who experienced anxiety with or without association
with a life-threatening illness.

Neuropsychopharmacology - Low doses of lysergic acid diethylamide (LSD) increase reward-related brain activity

BackgroundPsilocybin-induced mystical-type experiences are associated with lasting positive psychological outcomes. Recent studies indicate that trait mindfu...

In the study, people described both drug and NDE experiences that brought a more positive attitude to death, with less fear. People reported significant increases in psychological insight, welfare and meaning in their lives. ...

A single dose of the psychedelic drug psilocybin combined with supportive counseling leads to significant reductions in depressive symptoms, according to a new double-blind, placebo-controlled study. The findings have recently been published in eClinicalMedicine.…

Researchers in the United Kingdom studied whether the effects of psilocybin, a naturally occurring hallucinogenic drug, depend on the body mass index of the person, thereby requiring higher doses for the same effect in heavier people. The results showed that…

Background: Psilocybin, the primary psychoactive component of psychedelic ‘magic mushrooms’, may have potential for treating depressive symptoms, and consequent...

Many doctors treat depression with SSRIs, but could psychedelic medication be more effective? A study published in BJ Psych Open suggests that psilocybin, a psychedelic substance found in "magic" mushrooms, may be more beneficial than certain antidepressants…

Membrane-permeable psychedelics promote cortical neuron growth by activating intracellular serotonin 2A receptors.

BackgroundPsychedelic-assisted therapy [e.g., with lysergic acid diethylamide (LSD)] has shown promising results as treatment for substance use disorders (SU...

Abstract Background and aims Although numerous cultures have used psychoactive substances for spiritual, or entheogenic, purposes, little is known about contemporary entheogenic spirituality, particularly outside of the few traditions that retain sacramental…