High-Fat Diet and Antibiotics Cooperatively Impair Mitochondrial Bioenergetics to Trigger #Dysbiosis that Exacerbates Pre-inflammatory Bowel Disease
https://2medical.news/2020/07/21/high-fat-diet-and-antibiotics-cooperatively-impair-mitochondrial-bioenergetics-to-trigger-dysbiosis-that-exacerbates-pre-inflammatory-bowel-disease/
The clinical spectra of irritable bowel syndrome (#IBS) and inflammatory bowel disease (#IBD) intersect to form a scantily defined overlap syndrome, termed pre-IBD. We show that increased Enterobacteriaceae and reduced Clostridia abundance distinguish the fecal microbiota of pre-IBD patients from IBS patients. A history of antibiotics in individuals consuming a high-fat diet was associated with the greatest risk for pre-IBD. Exposing mice to these risk …
https://2medical.news/2020/07/21/high-fat-diet-and-antibiotics-cooperatively-impair-mitochondrial-bioenergetics-to-trigger-dysbiosis-that-exacerbates-pre-inflammatory-bowel-disease/
The clinical spectra of irritable bowel syndrome (#IBS) and inflammatory bowel disease (#IBD) intersect to form a scantily defined overlap syndrome, termed pre-IBD. We show that increased Enterobacteriaceae and reduced Clostridia abundance distinguish the fecal microbiota of pre-IBD patients from IBS patients. A history of antibiotics in individuals consuming a high-fat diet was associated with the greatest risk for pre-IBD. Exposing mice to these risk …