Diabetes Technology—Continuous Subcutaneous #Insulin Infusion Therapy and Continuous #Glucose Monitoring in Adults: An Endocrine Society Clinical Practice Guideline

http://press.endocrine.org/doi/10.1210/jc.2016-2534

Conclusions:
Continuous subcutaneous insulin infusion and continuous glucose monitoring have an important role in the treatment of diabetes. Data from randomized controlled trials are limited on the use of medical devices, but existing studies support the use of diabetes technology for a wide variety of indications. This guideline presents a review of the literature and practice recommendations for appropriate device use.

Use of #glucose-lowering drugs and risk of #fracture in patients with type 2 diabetes

http://www.sciencedirect.com/science/article/pii/S8756328216303593?via%3Dihub

Current use of sulphonylureas was associated with an increased risk of fracture in both male and female patients.

Current use of glitazones was associated with an increased risk of fracture in both men and women.

Ever use of sulphonylureas was not associated with an increased risk of fracture in patients with type 2 diabetes.

Advanced age, previous major osteoporotic fractures, falls and were all associated with an increased risk of fracture.

#Glucose Self-#monitoring in Non–Insulin-Treated Patients With Type 2 Diabetes in Primary Care Settings
A Randomized Trial
http://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2630691#162897085

Importance The value of self-monitoring of blood glucose (SMBG) levels in patients with non–insulin-treated type 2 diabetes has been debated.

Objective To compare 3 approaches of SMBG for effects on hemoglobin A1c levels and health-related quality of life (HRQOL) among people with non–insulin-treated type 2 diabetes in primary care practice.

Conclusions and Relevance In patients with non–insulin-treated type 2 diabetes, we observed no clinically or statistically significant differences at 1 year in glycemic control or HRQOL between patients who performed SMBG compared with those who did not perform SMBG. The addition of this type of tailored feedback provided through messaging via a meter did not provide any advantage in glycemic control

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Informational value of percent body #fat with body mass index for the risk of abnormal blood #glucose: a nationally representative cross-sectional study

http://bmjopen.bmj.com/content/8/4/e019200

64% of population with normal BMI classification had a high %BF. Prevalence of ABG in normal-weight group with high %BF (13.5%) is significantly higher than the overweight group with low %BF (10.5%, P<0.001). In an unadjusted model, the OR of ABG was significantly greater in adults at normal BMI with high %BF compared with individuals at normal weight with low %BF. In an adjusted model controlling for age, sex, race/ethnicity, first-degree-relative diabetes, vigorous-intensity activities and muscle strengthening activities, risks of ABG were greater in population with normal weight and high %BF (OR 1.55, 95% CI 1.01 to 2.38) and with overweight and low %BF (OR 1.17, 95% CI 0.69 to 1.98, P<0.05).

Conclusions Integrating BMI with %BF can improve in classification to direct screening and prevention efforts to a group currently considered healthy and avoid penalties and stigmatisation of other groups that are classified as high risk of ABG.

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Understanding of anti‐diabetic medication is associated with blood #glucose in patients with type 2 #diabetes: at baseline date of the KAMOGAWA‐DM cohort study

https://onlinelibrary.wiley.com/doi/abs/10.1111/jdi.12916

Poor understanding of anti‐diabetic medication (PUAD) was defined as discrepancy between the answer and the actual use of oral anti‐diabetic medication on the questionnaire. Poor blood glucose level was defined as HbA1c ≥8%

Among 479 patients, 40 patients (8.4%) were categorized into PUAD group. Hemoglobin A1c of patients with PUAD was higher than that of patients without (7.5 (1.3) vs. 7.2 (0.9) %, p = 0.041). In the propensity‐matched 74 patients, PUAD was associated with poor blood glucose level (odds ratio: 5.45, 95%CI: 1.54 – 25.8, p = 0.007) by logistic regression analysis.

Conclusion
Poor understanding of anti‐diabetic medication is associated with poor blood glucose level in patients with type 2 diabetes

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Assessment of Self-monitoring of Blood #Glucose in Individuals With Type 2 Diabetes Not Using #Insulin

https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/2717953

One recommendation is “avoid routine multiple daily self-glucose monitoring in adults with stable type 2 diabetes on agents that do not cause hypoglycemia.”1 This recommendation is based on robust evidence, including a Cochrane review of 12 randomized clinical trials with more than 3000 patients, showing no statistical difference between patients who do not self-monitor their blood glucose multiple times per day and those who do self-monitor their blood glucose multiple times per day in glycemic control, nor evidence of effects on health-related quality of life, patient satisfaction, or decreased number of hypoglycemic episodes.2

The aim of this study was to quantify the rate of use and cost of self-monitoring blood glucose supplies that are potentially used inappropriately, specifically focusing on test strips, the most costly supply for regular blood glucose monitoring

The #triglyceride- #glucose index is associated with the severity of hepatic #steatosis and the presence of liver #fibrosis in non-alcoholic fatty liver disease: a cross-sectional study in Chinese adults
https://2medical.news/2020/10/13/the-triglyceride-glucose-index-is-associated-with-the-severity-of-hepatic-steatosis-and-the-presence-of-liver-fibrosis-in-non-alcoholic-fatty-liver-disease-a-cross-sectional-study-in-chinese-adu/

The triglyceride-glucose index (TyG) is a reliable predictor of non-alcoholic fatty liver disease (NAFLD). Its association with the severity of hepatic steatosis and liver fibrosis in NAFLD is poorly understood. This study evaluated the relationship between these factors in NAFLD. ..The TyG index was significantly correlated with the severity of hepatic steatosis and the presence of liver fibrosis in patients with NAFLD. TyG quartile values …

Fasting plasma #glucose level in the range of 90 to 99 mg/dL and the risk of the onset of type 2 #diabetes: Population-based Panasonic cohort study 2

https://2medical.news/2021/10/17/fasting-plasma-glucose-level-in-the-range-of-90-to-99-mg-dl-and-the-risk-of-the-onset-of-type-2-diabetes-population-based-panasonic-cohort-study-2/

Visit-to-visit fasting blood #glucose variability and lifetime risk of #cardiovascular disease: a prospective study

https://2medical.news/2021/10/22/visit-to-visit-fasting-blood-glucose-variability-and-lifetime-risk-of-cardiovascular-disease-a-prospective-study/

#Light stimulation of mitochondria reduces blood #glucose levels

https://2medical.news/2024/02/28/light-stimulation-of-mitochondria-reduces-blood-glucose-levels/

Continuous #glucose monitoring and intrapersonal variability in fasting #glucose

https://2medical.news/2024/04/22/continuous-glucose-monitoring-and-intrapersonal-variability-in-fasting-glucose/