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Aldo Lorenzetti M.D, Internal Medicine & Hepatology, Milano - SIMEDET Delegate
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Early peripheral activity alters nascent subplate circuits in the #auditory cortex
https://2medical.news/2021/02/21/early-peripheral-activity-alters-nascent-subplate-circuits-in-the-auditory-cortex/

Cortical function can be shaped by sensory experience during a critical period. The onset of the critical period is thought to coincide with the onset of thalamocortical transmission to the thalamo-recipient layer 4 (L4). In early development, subplate neurons (SPNs), and not L4 neurons, are the first targets of thalamic afferents. SPNs are transiently involved in early development and are largely eliminated during development. Activation …