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Effect of Intra-Articular #Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With #Osteoarthritis
..Among participants with symptomatic radiographic knee osteoarthritis, the intra-articular administration of 100 μg of sprifermin every 6 or 12 months vs placebo resulted in an improvement in total femorotibial joint cartilage thickness after 2 years that was statistically significant, but of uncertain clinical importance; there was no significant difference for 30 μg of sprifermin every 6 or 12 months vs placebo. Durability of response also was uncertain.
https://jamanetwork.com/journals/jama/article-abstract/2752470 jiu
Effect of Intra-Articular #Sprifermin vs Placebo on Femorotibial Joint Cartilage Thickness in Patients With #Osteoarthritis
..Among participants with symptomatic radiographic knee osteoarthritis, the intra-articular administration of 100 μg of sprifermin every 6 or 12 months vs placebo resulted in an improvement in total femorotibial joint cartilage thickness after 2 years that was statistically significant, but of uncertain clinical importance; there was no significant difference for 30 μg of sprifermin every 6 or 12 months vs placebo. Durability of response also was uncertain.
https://jamanetwork.com/journals/jama/article-abstract/2752470 jiu