" Clinical Notes "
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" صدقةٌ جاريةٌ عن أرواحِ شهداء غزة ."🇵🇸

ادعوا لهم بالرحمة و المغفرة .
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■ Notes on peripheral nerve injury : -

C5, 6: Policeman tip position

C567: wrist drop

T1: Horner syndrome

C8T1: Claw hand deformity and horner syndrome.

Radial nerve : wrtist drop

Median nerve at elbow: FDP, pointing infex.

Ape like hand: median nerve at elbow(small muscles of hand).

Ape like hand, wasting of eminence:
1 Abductor
2 Flexor
3 Opponens: no opposition
4 Radial 2 lumbricals.

Median nerve at wrist : paralysis of above muscles
Radial deviation of hand :ulnar paralysis at elbow

Ulnar deviation of the hand: median n at elbow

Cardboard test: ulnar nerve paralysis of intrrossssi (ring, little, Index)

Froment test(adductor pollicis) thumb and index.

Flattening of hypothenar eminence and interossei hollowing : ulnar nerve

Foot drop : sciatic nerve and lateral popliteal n.
Paralytic equinovarus : longstanding lateral popliteal nerve

Lumber sympathectomy= Upper 3 lumber gangila in Burger's disease

Cervical sympathectomy = 2nd & 3rd thoracic ganglia except stellat ( raynaud's & hyperhydrosis)
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■ توضيح الإجابة : ده تفسير دكتور الهواري اللي سمعه هيعرف ده و مكتوبة في كتابه 😉

أنا بنفع استخدم أي واحد فيهم لأنه كل واحد فيهم effective
بس م ينفعش استخدم الاثنين مع بعض في آن واحد
طيب هو مين ttt of choice طبعاً plasma exchange
ليه ؟ لأنه أقل في side effects من أعراض الجانبية بتاعت IVIG
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دي أهم حاجة لازم تبص عليها عشان ال mcq
من كتاب دكتور الهواري
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■ Notes on IBS :-

♤   Abdominal pain is increased  after meal & stress & decreased by defecation

♤ IBS with constipation is the most common type

♤ the symptoms are more common in women
♤ IBS is a clinical diagnosis by exclusion of oragnic causes

♤ colonscopy is done if older > 50 years to exclude any pathology

♤ Rectal biopsy is done if frequency of defecation is a featute

♤ the 1st step in ttt is Reassurance with lifestyle modification 
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■ Notes on Esophageal diseases :-

● Achalasia :
♤ d.t abscent esophageal ganglion cell

♤ it is more common in middle aged female

♤ dyphagia is more for fluid

♤ LES pressure  is high

♤ it appears in barium swallow as bird's beak appearance or rat's tail appearance

♤ its manily treated by surgical ttt as myotomy & POEM

● GORD :-
♤ it is the most common cause of non cardiac chest pain

♤  it is common in pregnant women : 80%
♤ LES pressure is low

♤ Heartburn is the major feature ( 30%)

♤ chest pain is inceased by bending & starining & lying down & releived by antacids & nitates

♤ GORD is essentially a clinical diagnosis

♤ 24 hour PH monitoring is the most important investigation ( Goldstandard)

♤ Normal endoscopy does not exclude reflux disease

♤ it leads to IDA & barrett' esophagus & adenocarcinoma

♤  PPIs is the drug of choice in ttt especially
omeprazole  
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■ Notes on PUD :
♤ the most common site is duodenum

♤ Bismuth containing preparation was considered the DOC for ttt PUD

♤ triple therapy ( omeprazole & Clarithromycin & Amoxicillin ) is the most widely used & approved therapy be given for 7-14 days

♤ Levofloxacin is used in resistant cases of PUD

♤ the most common complication is GIT bleeding 

♤ the most common symptom in DU & GU is epigastric pain

♤  Endoscopy : the most sensitive & specific approach for examining the upper GIT 

♤ H.pylori is present in both GUs & DUs

♤ H.pylori infection : distal gastric cancer & PUs & antral gastritis & MALT lymphoma

♤ H Pylori Ag in stool is the most imporatnt investigation & for follow up of ttt
● DUs :
♤ the pain awake the patient from sleep & increased by fasting & decreased by meal & antacids
♤ more common on O blood group

● GUs predispose to malignant change 

♤ NSAIDs inhibit Cox1 in stomach & it leads to GIT bleeding & Perforation 

♤ Nausea & wt loss are more with GU patients
♤ sudden onset of symptoms indicate perforation
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" Clinical Notes " pinned «■ Notes on GIT internal medicine :- ● IBD : ○ MCQ on IBD : https://t.me/med_Notes2/353 ○ UC : https://t.me/med_Notes2/348 ○ CD : https://t.me/med_Notes2/351 ● PUD : https://t.me/med_Notes2/335 ● Esophageal diseases : https://t.me/med_Notes2/334…»
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Itchiness is a prominent symptom in all cases of cholestasis , which drug can reduce itchiness ?
Anonymous Quiz
48%
Cholestryamine
1%
Ca supplements
2%
Vit K
49%
Nothing is done it goes away when cholestasis improves
5
Kayser-Fleischer rings plus typical motor neurologic abnormalities or a decrease in which of the following are nearly pathognomonic for Wilson disease?
Anonymous Quiz
20%
Cupper
1%
K
78%
Ceruloplasmin
0%
Transaminases
3
The Goldstandard in diagnosis of GORD is
Anonymous Quiz
6%
Barium meal
85%
24 h ph monitoring
8%
Colonscopy
1%
CT & MRI on stomach
1
H pylori infection can be predispose to except
Anonymous Quiz
3%
Antral gastritis
3%
GUs
90%
Proximal gastric cancer
3%
MALT lymphoma
Which of the following occurs in 15 to 30% of patients treated with Heller myotomy for achalasia?
Anonymous Quiz
2%
Death
22%
Mucosal perforation
66%
GERD
10%
Dimishing efficacy
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A patient who has symptoms of GERD is prescribed a trial of PPIs . One month later the symptoms have not improved despite treatment, and findings on endoscopy are unremarkable. Which of the following is the most appropriate next step in management?
Anonymous Quiz
10%
Barium swallow
19%
Repeated endoscopy in one month
66%
24 h PH testing
5%
Esophageal manometry
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■ Notes on IBD :-
● UC :
♤ the disease starts distally in Rectum then spreads proximally

♤ Bleeding per rectum is the most important feature

♤ perforation is the most dangerous of the local complications

♤ Increase risk of cancer colon more than CD

♤ somking is a protective for UC

♤  decrease of Albumin is due to poor nutrition & PLE & -ve ARP

♤ fecal lactoferrin is a highly sensitive & specific marker for detecting intestinal inflammation

♤ colonoscopy is the most important investigation is used to assess disease extent & activity

♤ barium enema :
lead pipe appearance ( loss of haustration + narrowing the lumen)
PseudoPolyp

♤ 5-ASA Agents is the mainstay of ttt in mild to moderate UC

♤GCs is used in acute flares only not in remission manitenance ( moderate to severe UC)

♤ metronidazole & ciprofloxacin is the most commonly used
مقارنة بين UC & CD مهمة
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■ Notes on CD :-

♤ terminal ileum & right colon ( ileocolonic) are most commonly involved

♤ cobblestone appearance is the characteristic of CD

♤ pain  & tenderness in right iliac fosaa = acute appendicitis is relieved by defecation

♤ Malabsorption syndrome is more common with CD ( decrease in Na & mg & ca & albumin& fat soluble vitamins )

♤ it lead to intestinal obsdruction & fisula formation

♤ Colonoscopy is the most important investigation

♤ barium enema : severe narrowing of the lumen ( string sign )

♤ AZA as maintenace therapy in UC & CD & treating active perineal disease & fistula in CD

♤ Ciprofloxacin & metronidazole are effective in peri anal CD

♤ Avoid antidiarrheal durgs in toxic megacolon lead to precipitate toxic megacolon with colonic inflammation 
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