Internal medicine hub
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IM tips & Q-bank for SMLE and part
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25-year-old presents with dark urine and confirmed blood in the urine test, 3 weeks after a throat infection. What is the most likely diagnosis?
Anonymous Quiz
2%
Burger's disease
15%
IgA nephropathy
81%
Post-streptococcal glomerulonephritis
3%
Membranous glomerulonephritis
๐Ÿฆ  Poststreptococcal GN may occur 1-6 weeks after resolution of infection:

โ€ข 1-2 weeks after pharyngitis
โ€ข 4-6 weeks after impetigo
โ€ข 3-6 weeks after a pyoderma
patient with rheumatoid arthritis (RA) who is on methotrexate and was previously in remission now has elevated LFTs. What is the next step in management?
Anonymous Quiz
9%
Start glucocorticoids
61%
Stop methotrexate
11%
Investigate for hepatitis infection
19%
Switch to Azathioprine
๐Ÿ’Š Methotrexate & RA:

- First DMARD given for RA
- Maximum dose is 25 mg per week
- Hold for 1-2 after seasonal influenza vaccination
- Reported to have a protective effect in reducing the risk of DM in patients with inflammatory disease (RA)
- Folate supplementation may reduce GI side effects of methotrexate (1 mg/day or 5 mg/week)
- Hepatic toxicity usually resolves within 10 days
- Antidote: LEUCOVORIN
โค1๐Ÿ‘1
Indian male presents with weight loss and hemoptysis and has a right-sided pleural effusion, Based on the most likely diagnosis in such a case, most sensitive test from pleural fluid?
Anonymous Quiz
6%
Glucose less than 100
15%
High lymphocyte count
34%
AFB
45%
ADA
47-year-old alcoholic patient presents with a 6-week history of weight loss, fever, and right hypochondrium pain. Lab results and imaging findings include: Alpha fetoprotein: 120 ng/mL (normal: 0-40 ng/mL)
Abdominal ultrasound: Ascites and a focal liver lesion in a cirrhotic liver.
Which of the following is the most likely diagnosis?
Anonymous Quiz
6%
Liver abscess
8%
Pancreatic cancer
11%
Hydatid liver disease
76%
HCC
patient presents with sudden severe chest pain, shortness of breath, a systolic ejection murmur BP 220/100. What is the most appropriate immediate
management?
Anonymous Quiz
30%
Nitroglycerin with esmolol
62%
Labetalol followed by nitroprusside
5%
Nifedipine๏ปฟ๏ปฟ๏ปฟ
3%
Hydralazine
๐Ÿ‘1
๐Ÿšซ Donโ€™t be tricked:

- in aortic dissection:
give BB first then vasodilation (nitroprusside)
- in Pheochromocytoma: give Alpha-blocker then BB
- in Myxedema Coma:
give hydrocortisone first then levothyroxine
๐Ÿ‘2
43-year-old male presented to the ER with syncope and hypotension. ECG showed supraventricular tachycardia (SVT). What is the best next step?
Anonymous Quiz
46%
IV adenosine
5%
Defibrillation
44%
Cardioversion
5%
IV metoprolol
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30F with RA presents with SOB and dry cough for 3 months
denies fever or weight loss examination: cyanosis, digital clubbing, and bibasilar end-inspiratory crackles (velcro crackle). Likely diagnosis?
Anonymous Quiz
2%
Lung abscess
21%
Bronchiectasis
8%
Bronchogenic carcinoma
69%
Interstitial pulmonary fibrosis
๐Ÿ‘1
๐Ÿซ Pulmonary manifestations in patients with RA may include:
- Interstitial lung disease
- Pleura inflammation (thickening & effusions)
- Pulmonary hypertension
- Caplan syndrome
๐Ÿ™1
ู…ุจุฑูˆูƒ ู„ุฌู…ูŠุน ุงู„ู…ู‚ุจูˆู„ูŠู† ูˆุญุธ ุงูˆูุฑ ู„ู„ุจู‚ูŠุฉ ๐Ÿ™Œ๐Ÿปโค๏ธโค๏ธ
#matching2025
โค4
When should an adult with FSGS be considered glucocorticoid-resistant?
Anonymous Quiz
19%
4 weeks
41%
8 weeks
32%
12 weeks
8%
16 weeks
patient diagnosed with cough variant asthma on albuterol
Initially symptoms improved, but they still complain of cough, need to clear the throat, especially at night & when lying down. Next step?
Anonymous Quiz
12%
Add long-acting beta-agonist
41%
Add inhaled corticosteroid
44%
Add PPI
3%
Add oral steroid
๐Ÿซ Asthma subtypes & variants
45 woman presents with weight gain, facial rounding and proximal muscle weakness. What is the most appropriate initial investigation to evaluate her condition?
Anonymous Quiz
47%
24-hour urinary free cortisol
27%
Early morning serum cortisol
10%
Plasma ACTH level
16%
Low-dose dexamethasone suppression test
๐Ÿ’ก Remember:

Avoid clarithromycin and levofloxacin based regimens in the absence of demonstrated antibiotic susceptibility.

First-line eradication regimens for H. pylori infection is optimized bismuth quadruple therapy for 14 days (PPI, bismuth subcitrate, tetracycline and metronidazole)

**Previous question is from an old SMLE Q-bank ๐Ÿ˜
ูƒู„ ุงู„ุชูˆููŠู‚ ู„ุฌูˆู†ูŠูˆุฑ ุงู„ู…ุฏุณู† ููŠ ุงุฎุชุจุงุฑู‡ู… ุงู„ูŠูˆู… ูˆุจูƒุฑู‡๐Ÿ™Œ๐Ÿปโค๏ธ
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