📣 Research Talks:
▪️ Maofu Liao, PhD, Harvard Medical School, Cryo-EM reveals how ABC transporters move substrates
▪️ Doreen Matthies, PhD, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cryo-EM of membrane proteins in a lipid environment
▪️ Mahmoud Nasr, PhD, RPh, Harvard Medical School
Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.

❗️ Space is limited. Protein Society Members have priority registration.

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#Вебинар #обучение #Webinar

Cells in Motion - Shaker and Bioreactor optimization

🗓 Wednesday, April 28, 2021
⏰ 8 am PDT, 11 am EDT, 5 pm CEST

📍 Key learning objectives
▪️ Why shake or stir cells and an outline of system specific differences
▪️ Learn how to identify the right cultivation method, vessel type, vessel material, and instrument configuration for your specific needs
▪️ Learn how to define and optimize important parameters to improve culture results – incl. Tips & Tricks
▪️ Learn about feeding possibilities in shake flasks and bioreactors and their impact on your culture

👤 Target groups:
Experienced scientists looking for tips and tricks to improve their processes
Scientists new to cultivating cells in suspension in shakers and/or bioreactors.

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#Webinar #обучение #Eppendorf

Access insights into the complex tumor microenvironment (TME) and gain a greater understanding of the role of heterogeneity in immune checkpoint responses. This virtual seminar will provide a useful tool for comprehensive analyses of immune cells in the TME.

🗓 27 April, 3:00 pm PST
🗓 28 April, 7:00 am JST

Key topics:
▪️ Application of tissue and tumor dissociation and preservation of research tissue samples.
▪️ Biomarker prediction and resistant mechanisms in PD-1 blockade.
▪️ Best practices to design and analyze immune cells in the TME.

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#Wiley #Webinar #вебинар #обучение

Everyday Cell Culture Practice – Improve Reproducibility

🗓 Thursday, May 6, 2021
⏰ 7 am PDT, 10 am EDT, 4 pm CEST
🧑‍💻 live or recorded

Key topics:
▪️ Effects of passage numbers
▪️ Correct use of FBS
▪️ Get to know your cells. Documentation and monitoring
▪️ Cell line authentication methods
▪️ Mycoplasma test methods

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#webinar #eppendorf #обучение #вебинар

Five major steps in drug discovery

🗓 Wed, May 12, 2021
⏰ 12:00 PM - 1:00 PM MSK

In this free webinar you will learn about:
💊 How to extract, concentrate, purify, formulate and characterize molecules
💊 Tips for achieving quick, reliable purifications with flash chromatography
💊 How to optimize ingredient formulation with spray drying and microencapsulation
💊 Case study I: How to synthesize or extract GlabrescionB
💊 Case study II: How to spray dry roselle

#webinar #вебинар #обучение #BUCHI

DATE: May 19th 2021
TIME: 10:00 CET

In this webinar you will learn:
✅ How to image multiple fluorescent probes In Vivo with the removal of background fluorescence using Spectral Unmixing Technology;
✅ Gather insight into imaging multiple cell types in the same animal using Bioluminescence;
✅ Novel luciferases and luciferin mutants and how they have been used to image multiple cell types in the same animal.

#обучение #вебинар #webinar #PerkinElmer

🗓 Tuesday, May 18, 2021
⏰ 10:00 am - 11:00 am
🧑‍💻 Online webinar

Join this webinar with Associate Professor Kristin Sainani to learn the steps of a complete data analysis, using real data on mental health in athletes. She will give practical, hands-on tips for how to approach each step of the analysis and how to improve rigor and reproducibility of your research.

You Will Learn:
✅ What steps are needed for an effective data analysis
✅ The importance of cleaning, checking, understanding, and plotting data
✅ How to improve the rigor and reproducibility of your research

#вебинар #обучение #webinar #Stanford

The power of ONE: Immunology in the age of single-cell genomics

🗓 May 25, 2021
⏰ 6 AM PDT, 9 AM EDT, 2 PM BST, 4 PM IDT

Key Learnings:
✅ How single-cell genomics holds the potential to revolutionize the way we characterize complex immune cell assemblies and study their spatial organization, dynamics, clonal distribution, pathways and crosstalk
✅ Learn how recent single-cell genomic studies are changing our perspective of various immune-related pathologies from cancer to autoimmune disease and neurodegeneration
✅ Learn about recent and forthcoming technological and analytical advances in single-cell genomics and their huge potential impact on the future of immunology research and immunotherapy

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#обучение #вебинар #webinar #CurrentProtocols

Live Webinar: Enhancing the Predictability of Preclinical Development

DATE: May 26, 2021
TIME: 8AM PST, 11 AM EST, 4 PM BST, 5PM CEST

Preclinical studies enable evaluation of drug candidates for both efficacy and safety within biological model systems. Physiological relevance of the models used can closely mimic the biochemical pathways, metabolism, and physiology of humans. Hence, primary cells, 3D cell culture / tissues, and cell-based assays comprise relevant model systems.

✅ How to evaluate models to establish robust and reliable preclinical investigation of drug candidates prior to entering clinical trials
✅ How to gain an understanding of the advancements in preclinical model systems and assays
✅ What to consider from the latest innovations and impact on bioanalytical assays.

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#обучение #вебинар #webinar #PerkinElmer

DATE: 26 May 2021
TIME: 10:00 AM ET | 4 PM CET

Drug development faces a significant challenge in that only 1 in 10 candidates make it to the market, often due to safety/toxicity issues rather than efficacy. Adoption of early assessments to de-risk drug candidates by identifying and de-prioritizing those with potential safety issues is of paramount importance.
Join this live webinar where Dr. Peterson will discuss how in vivo fluorescence probes and strategies can be used in early drug screening.

✅ Overview of the range of animal models and therapeutic areas supported by fluorescent imaging and imaging probes
✅ Liver safety/toxicology imaging of the effects of chemical agents
✅ Characterization of kidney safety/toxicology of Cyclosporin A and Rapamycin
✅ Live Q & A

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#вебинар #обучение #Webinar #PerkinElmer

Chromatography Virtual Academy: Flash cartridges, prep HPLC columns & co.

May 26th from 11:00 to 12:00 CEST

In this free webinar, gain valuable information on handling and use of chromatography consumables.
Ensure you are making the correct choices for your application from the wide selection of chromatography cartridges and columns available.

In the second part of our 4-part chromatography lecture series, join our purification specialist, Dr. Birke Götz in learning about:
✔️ Benefits and limitations of using flash cartridges, glass columns and prep HPLC columns
✔️ Equilibration, cleaning and storage of flash cartridges and prep HPLC columns
✔️ Dry and slurry packing of glass columns
✔️ Solid sample loading for flash applications
✔️ Liquid sample loading for flash and prep HPLC applications

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#обучение #вебинар #Webinar #Buchi

Watch on demand: Characterising cancer cell states using spatial transcriptomics

Intratumor heterogeneity is a recognized cause of cancer treatment failure. While much of tumor heterogeneity is genetic in nature, recent work using single-cell RNA-Seq has detected a hitherto underappreciated level of transcriptional heterogeneity, leading to the notion of cancer cell states. Studies in melanoma, glioblastoma, and head and neck cancer among others have identified sets of cancer cell states, many of which relate to processes specific to the cell of origin.

Join this virtual seminar to:
✅ Learn about how single-cell RNA-Seq and Spatial Transcriptomics can be integrated
✅ Understand how cell states can be defined using gene modules
✅ Explore how cancer cell states may be related to the tumor microenvironment
✅ Consider the conservation of cancer cell states across diverse cancer types

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#обучение #вебинар #webinar #CurrentProtocols