Complexity
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#biotechnology #systems #intermediate

Say 'hi!' to high-fidelity lossless long read capture. There was a flaw with nanopore. Particularly that the confidence score (PHRED) was plateauing at 70% accuracy. The #F_score for SBX is >99.80% for single nucleotide variants. >99.56% for insertions delitions. 7 genome in an hour at 30x depth with more than 5 billion duplex in an hour [1]. I think after this, only flash sequencing can beat the record.

Last record was set by #Nanopore with #NVIDIA high performance parallel computing at 5 hours and 2 minutes in 2022 [2]. This means with #expandomer(s), it will be around 7 genomes sequenced in less than 4 hours. While the entire variant discovery pipeline under 5 hours. Kinda excited about the data. This is rapid point of care. Dope!

https://youtu.be/G8ECt04qPos

Sources:

[1]
https://sequencing.roche.com/global/en/article-listing/sequencing-platform-technologies.html

[2]
K. Powell, “World Record-Setting DNA Sequencing Technique Helps Clinicians Rapidly Diagnose Critical Care Patients,” NVIDIA Blog, Jan. 12, 2022. https://blogs.nvidia.com/blog/world-record-genome-sequencing-parabricks/

#EN
#python #bioinformatics #basic #practice #resources


#general

Biopython cook book. Use this resource to do and understand basic python implementation of Bioinformatics Algorithms.

https://biopython.org/docs/latest/Tutorial/chapter_cookbook.html

#EN #pyzero #bioal
#physics #intermediate #books

Physics, Vol. 1 and 2
Halliday, Resnik, Krane

This is a good introductory course. Chapters on relativity and modern physics are excellent.

Please update links if expired.

Vol. 2
https://libgen.gs/edition.php?id=138009520

Vol. 1
https://libgen.gs/edition.php?id=138047924

#EN
#biology #chemistry #intermediate #books

Lehninger Principles of Biochemistry, 8
Nelson, Cox

Reference text in #biochemistry.

Please update links if expired.

https://libgen.gs/edition.php?id=142692330

#EN
🔥1
#biology #intermediate #books

Biology 11 and 12
Various, NCERT

Reference introductory text books in Biology.

Please update links if expired.

https://libgen.gs/edition.php?id=140505207

https://libgen.gs/edition.php?id=140505208

#EN
🔥1
#stem #interdisciplinary #intermediate #books

An Introduction to Molecular Biotechnology
Wink

Undergraduate text in #biotechnology.

Please update links if expired.

https://libgen.gs/adsd9ca2e224b7c17b1459297f427af89e3WSIBLFPQ

#EN
#course #physics #maths #advanced

Gore for #MIT_OCW.

Introduction to #systems #biology.

Foundational concepts are introduced for students of #interdisciplinary background with application of systems theory.

https://www.youtube.com/playlist?list=PLUl4u3cNGP63OI3pSKo8Ha_DFBMxm23xO

#EN
#memes #censorship #resources

Working sci-hub mirrors.
https://scihub.help/

Or use Telegram bot here
@scihubot

#EN
#documentary #stem #humanities #neurosciences #scifi

The eternal drama.

It is otherwise an underground work with screening at science festivals. So unless the director leaks out the original high-res, following are the steps you can take to ensure that it remains with you, if not for a DMCA takedown (#censorship).

Movie is available on YT. I have saved it.
Step 1: Scrape 1080 without sound (example: keepvid, savefromnet or ytvideodownloader, whichever gives you the best quality)
Step 2: Scrape audio at maximum bitrate (same as step 1).
Step 3: Scrape EN and RU subtitles (opensubtitles or yify subs).
Step 4: Join AV with favorite tools (Adobe Premier Rush, or Sony) *

*don't use windows moviemaker. It is just like the Windows operating system, but much worse.

The original documentary is in Polish.

Use KM player 64, for double subtitles. English subtitles maybe delayed by 10 seconds. Use '[' ']' keys to delay or advance for subtitle synchronisation.

https://youtu.be/w8jEC97xGZA

#EN