4. In a one-compartment open model, elimination follows which type of kinetics?

5. What is the primary route of drug elimination in the body?

6. Which of the following pharmacokinetic parameters represents the volume of distribution?

7. The elimination rate constant (Ke) is calculated using which equation?

8. The half-life (t1/2) of a drug is dependent on which of the following?

9. Area Under the Curve (AUC) is used to measure:

10. Which of the following parameters is used to determine drug clearance (Cl)?

11. A drug with a high volume of distribution (Vd) is likely to:

12. What is the key characteristic of intravenous bolus administration?

13. Which factor influences the bioavailability of a drug?

14. Which pharmacokinetic model considers actual physiological processes?

15. Which drug administration route avoids first-pass metabolism?

16. Which pharmacokinetic process primarily follows first-order kinetics?

17. What is the primary advantage of intravenous infusion over bolus injection?

18. Which factor increases renal drug clearance?

19. The area under the curve (AUC) is mainly used to assess which pharmacokinetic property?

20. Which parameter determines how quickly a drug is removed from the body?

21. Which drug is most likely to have a low volume of distribution (Vd)?

22. What does a high plasma protein binding of a drug indicate?

23. In extravascular drug administration, what determines the absorption rate?

24. What is the key factor affecting first-pass metabolism?