If drug have very small volume of distribution it is likely that the drug
Anonymous Quiz
28%
Has short biological half life
49%
Does not accumulate in various tissue and organ
16%
Not bioavailable
7%
will not be effective
Which one of the following receptors is NOT a ligand-gated ion channel receptor. (GPAT 2015)
Anonymous Quiz
25%
Nicotinic Receptor
21%
5HT3-Receptor
23%
GABA-A- Receptor
31%
H2- Receptor
The increase in concentration of second messengers (cAMP, cGMP, Ca2 etc.) leads to: (GPAT 2013)
Anonymous Quiz
30%
Inhibition of intracellular protein kinases and protein phosphorylation
56%
Protein kinases activation and protein phosphorylation
10%
Blocking of interaction between a receptor and an effector
4%
Antagonism with endogenous
cyclic AMP (cAMP) Is an important second messenger in signal transduction pathways. Which . enzyme catalyzes the generation/accumulation of cAMP after a receptor-ligand interaction? (GPAT 2015 )
Anonymous Quiz
20%
Protein kinase A
47%
cAMP phosphodiesterase
13%
Guanylyl cyclase
20%
Adenylate cyclase
👍2🥰2
Wheal and Flare” reaction is characteristic reaction associated with identification of: (GPAT 2022)
Anonymous Quiz
37%
Type-1 hypersensitivity reaction
37%
Type-2 hypersensitivity reaction
21%
Type-3 hypersensitivity reaction
5%
Type-4 hypersensitivity reaction
GPAT/NIPER study point
ANS PART 1 PHARMACOLOGY .pdf
Read this pdf ❗️❗️& clear the concept of muscarinic receptor
👍1
Phase solubility Analysis curve is not a good tool for :
Anonymous Quiz
16%
Complex formation
48%
Bioavailability determination
24%
Polymorph detection
12%
Impurity detection
👍2
The unequal attractive forces acting on the molecules at the surface of the liquid gas interface
when compared with molecular forces in the bulk of the liquid is due to
when compared with molecular forces in the bulk of the liquid is due to
Anonymous Quiz
28%
Absence of adhesive force of attraction
32%
Less adhesive force of attraction
31%
Absence of cohesive force of attraction
10%
Less cohesive force of attraction
When adhesive attractions between molecules of different species exceed cohesive attraction
between like molecules, the deviation according to Raoult's law is said to be
between like molecules, the deviation according to Raoult's law is said to be
Anonymous Quiz
19%
Partial
47%
Positive
16%
Neutral
18%
Negative
👍1
Which of the following statement is NOT true regarding bulkiness?
Anonymous Quiz
17%
The reciprocal of bulk density is the bulkiness
38%
Bulkiest substance will require a container larger than required for a less bulky substance
28%
Smaller particles shift between larger ones and increase bulkiness
17%
Bulkiness increases with a decrease in particle size
The shelf life of medicine is defined as :
Anonymous Quiz
19%
Time required for 10% degradation of the drug
30%
Time required for 50% degradation of the drug
37%
Time required for 90% degradation of the drug
14%
Time required for 100% degradation of the drug
Following statement is more accurate with respect to the limitations of the Arrhenius
relationship for stability prediction
relationship for stability prediction
Anonymous Quiz
24%
Order of degradation will alter at a higher temperature
41%
Equal moisture concentrations will be mentioned at different temperatures
23%
Less relative humidity and oxygen solubility at a higher temperature
12%
Same degradation mechanisms may predominate at different temperatures
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Least potent cardiac depressant drug [NIPER JEE 2018]
Anonymous Quiz
18%
Quinidine
31%
Procainamide
26%
Disopyramide
24%
Verapamil
The drug of choice for Torsades de pointes [NIPER JEE 2020]
Anonymous Quiz
18%
Sotalol
22%
Ibutilide
43%
disopyramide
17%
Magnesium
Which drug having anti-inflammatory and analgesic properties [NIPER JEE 2022]
Anonymous Quiz
8%
Tramadol
22%
Morphine
49%
Ibuprofen
21%
Paracetamol
👍1