Carrier-mediated transport that follows order kinetics at saturation concentration is?
Anonymous Quiz
36%
First
24%
Second
30%
Zero
10%
Pseudofirst
👍1
8. Carrier-mediated transport follows kinetics of (NIPER 2012)
Anonymous Quiz
54%
Zero order
29%
First order
11%
Pseudofirst order
7%
Michaeles-Menten
For very weak acidic drugs. With pKa >8. (GPAT 2021)
Anonymous Quiz
36%
They are unionized at all pH, hence absorption is rapid and independent of GI pH
23%
They are affected by changes in pH, hence absorption is pH dependent
28%
They are ionized in the entire pH range of GIT, hence poorly absorbed from GIT
13%
They are ionized in the gastric pH, hence better absorbed from the stomach
👍2
If drug have very small volume of distribution it is likely that the drug
Anonymous Quiz
28%
Has short biological half life
49%
Does not accumulate in various tissue and organ
16%
Not bioavailable
7%
will not be effective
Which one of the following receptors is NOT a ligand-gated ion channel receptor. (GPAT 2015)
Anonymous Quiz
25%
Nicotinic Receptor
21%
5HT3-Receptor
23%
GABA-A- Receptor
31%
H2- Receptor
The increase in concentration of second messengers (cAMP, cGMP, Ca2 etc.) leads to: (GPAT 2013)
Anonymous Quiz
30%
Inhibition of intracellular protein kinases and protein phosphorylation
56%
Protein kinases activation and protein phosphorylation
10%
Blocking of interaction between a receptor and an effector
4%
Antagonism with endogenous
cyclic AMP (cAMP) Is an important second messenger in signal transduction pathways. Which . enzyme catalyzes the generation/accumulation of cAMP after a receptor-ligand interaction? (GPAT 2015 )
Anonymous Quiz
20%
Protein kinase A
47%
cAMP phosphodiesterase
13%
Guanylyl cyclase
20%
Adenylate cyclase
👍2🥰2
Wheal and Flare” reaction is characteristic reaction associated with identification of: (GPAT 2022)
Anonymous Quiz
37%
Type-1 hypersensitivity reaction
37%
Type-2 hypersensitivity reaction
21%
Type-3 hypersensitivity reaction
5%
Type-4 hypersensitivity reaction