GPAT/NIPER study point
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Discussion of major subjects of GPAT/NIPER
Discussion of pyq of both GPAT /NIPER
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RESINOUS_DRUGS_PHARMACOGNOSY_FOR_GPAT,NIPER,DI,PH(1).pdf
8.1 MB
RESINOUS_DRUGS_PHARMACOGNOSY_FOR_GPAT,NIPER,DI,PH(1).pdf
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GPAT 2013: The most widely used agent for the treatment of acute gout arthritis is…
Anonymous Quiz
19%
Indomethacin
41%
Allopurinol
34%
Colchicine
5%
Probenecid
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Correct Answer - C
Ans. is 'c' i.e., colchicine

Management of gout
Treatment of acute gout
To provide rapid and safe pain relief Drugs used are :

i) NSAIDs:
These are the most frequently used drugs to treat gout because they
are so well tolerated.

Indomethacin is the agent of choice but other NSAIDs may be just as effective.

Aspirin is usually avoided because low doses of aspirin aggravate hyperuricemia.

ii) Colchicinee:
Colchicine is effective but less well tolerated than NSAIDs

iii) GlucocorticoidsQ:
Usually reserved for patients in whom colchicines or NSAIDs are
contraindicated or ineffective.

Treatment of chronic gout (maintain serum urate levels at 5.0
mg/dl or less)
AllopurinolQ:
Xanthine oxidase inhibitor
Agent of choice for most patients with gouty' Uricosuric agentsProbenecid2
SulfinpyrazoneQ

Treatment of gout according to the stage

Asymptomatic
hyperuricemia
No treatment indicated, the
causes should be
determined and any
associated problem should
be addressed rigorously)
Acute gouty
arthritis
NSAIDs or colchicines or
glucocorticoid
Intercritical period
Prophylactic colchicines (to
reduce further attacks)
Acute tophoaecous gout
Urate lowering
drug (allopurinol or probenecid,
sulfinpyrinazole)
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anticoagulant, fibrinolytics, anti-platelet drugs.pdf
9.9 MB
anticoagulant, fibrinolytics, anti-platelet drugs.pdf
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Urate transporter inhibitor used as, an antigout drug is [NIPER 2019]
Anonymous Quiz
11%
Lesinurad
51%
Allopurinol
24%
Febuxostat
14%
Colchicine
End capping of silica in reverse phase chromatography stationary phase is done to block (niper 2012)
Anonymous Poll
29%
Si of silica
31%
OH of silica
26%
OH of bonded phase
14%
Protect the bonded phase
Conversion of a carbonyl functionality directly to its hydrocarbon in basic media can be achieved by [GPAT 2019]
Anonymous Quiz
28%
Lithium aluminium hydride reduction
31%
Clemmensen reduce lion
16%
Sodium borohydride reduction
24%
Wolf Kishner reduction
Which of the following rearrangement involves migration of a group from carbon to electron deficient nitrogen (GPAT - 2020)
Anonymous Quiz
8%
Wilgerodt rearrangement
31%
Baeyer villiger, rearrangement
31%
Pinacol-pinacolone rearrangement
30%
Beckmann rearrangement
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https://youtu.be/wIMlKCwDT3g?feature=shared

If your mcq is going wrong then you should watch this lecture