💌 لديك رساله جديده :
ماكو مايند ماب للملتبل مايلاوما ؟
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cell membrane enzyme disorders
#med

blood transfusion

Blood transfusion
جعفر_صادق

ولاتنسون الmost common type هو الIGG

گال عليها مهمة

محاضرة د.حيدر العيداني الHyponatremia
#med

----RA---
RF not specific,
ACCP 98%specific مهم

--JIA--
Rf usual
postive with polyarthritis

20% uevitis ANA postive mostly with oligoarthritis less than 5 joint

Seronegative dis all RF negative
Usual assocciated with HLA -B27

1-Ankalosing spondylitis
assocciated with
HLA -B27 positve 90%
لكن ايضا نحتاج لclinical feature

2-Reactive arthritis
assocciated or not with
HLA B27
Clinical: diarrhea( infection) ,STD
arthritis

If  arthritis+ conjuctvitis , urethritis become Reiter syndrome

3-entropathic arthritis
assocciated with inflammtory bowel dis
(chron, ulcerative colitis)

4-psoriatic arthritis
assocciated with
envionmental(psoriasis and steptopharyngial )  and gentic  factor ( HLA -B27,38 ,39,57)
diagnosis clinical by Caspar. C

*
SLA

ANA senstive 95%
AdsDNA specific95%
A smooth muscle A most specif
anti-Ro (neonatal )
⬇️C3,C4
****
Drug induce Lupus- antihiston A
Normal C3,C4
****
Antiphosphlipid syndrome

ANA not specific
anticarodiolipin -specific
Lupus anticoagulant-specific
B2 globulin

***
Scleroderma (systemic sclrosis)

ANA  not specific

DCSS --ant Scl-70 A
LCSS(CREST)_anticenteromere

Skin biopsy ..

**
Sjogren syndrome

ANA , RF -- Not specific
Anti_RO

Anti- La antibody -specific

diagnosis by lip biopsy

****

Polymyositis --muscle biopsy

dermatomyositis--
Gottron papules pathgnmonics.
Muscle biopsy
*
Behcet syndrome

assocciated with HLA 51
Pthargy test


**

Vasculitis

RF ,ANA-- NOT specific
ANCA -- very important

*ANCA -C  ,PR3 -wegener dis
ANCA- P Churg-Strauss s
Negative ANCA _ microscopic p

HUS vs ITP