✳️ Extra-hepatic Manifestations of Chronic HCV Infection
1. Mixed Cryoglobulinemia / Vasculitis
2. Non-Hodgkin B-cell Lymphoma
3. Insulin resistance / Type 2 Diabetes Mellitus
4. Membranoproliferative Glomerulonephritis
5. Sjӧgren’s syndrome and Sicca symptoms
6. Autoimmune thyroid disease
7. Porphyria cutanea tarda
8.Lichen planus / skin disorders
9. Hematologic disorders (e.g., thrombocytopenia)
10. Neuropathy / neurological disorders
11. Cardiovascular disease associations
12. Other autoimmune or rheumatologic conditions
13. Metabolic alterations (lipid abnormalities)
✳️ Extra-hepatic Manifestations of HBV Infection
1. Serum-sickness–like syndrome
2. Polyarteritis nodosa (PAN)
3. Membranous Glomerulonephritis/nephropathy
4. Cryoglobulinemic vasculitis (less consistent)
5. Non-rheumatoid arthritis / polyarthritis
6. Non-Hodgkin lymphoma (less common)
7. Aplastic anemia / hematologic abnormalities
8. Papular acrodermatitis (Gianotti-Crosti syndrome)
1. Mixed Cryoglobulinemia / Vasculitis
2. Non-Hodgkin B-cell Lymphoma
3. Insulin resistance / Type 2 Diabetes Mellitus
4. Membranoproliferative Glomerulonephritis
5. Sjӧgren’s syndrome and Sicca symptoms
6. Autoimmune thyroid disease
7. Porphyria cutanea tarda
8.Lichen planus / skin disorders
9. Hematologic disorders (e.g., thrombocytopenia)
10. Neuropathy / neurological disorders
11. Cardiovascular disease associations
12. Other autoimmune or rheumatologic conditions
13. Metabolic alterations (lipid abnormalities)
✳️ Extra-hepatic Manifestations of HBV Infection
1. Serum-sickness–like syndrome
2. Polyarteritis nodosa (PAN)
3. Membranous Glomerulonephritis/nephropathy
4. Cryoglobulinemic vasculitis (less consistent)
5. Non-rheumatoid arthritis / polyarthritis
6. Non-Hodgkin lymphoma (less common)
7. Aplastic anemia / hematologic abnormalities
8. Papular acrodermatitis (Gianotti-Crosti syndrome)
👍2
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3 MB
Acute-on-chronic liver failure (ACLF): pathophysiological mechanisms and clinical management.
Nature Gastro&Hep Jan 2026
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BMJ November 2025
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JAMA November 2025
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1.1 MB
Potassium-competitive acid
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2.8 MB
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infection among individuals with obesity: a systematic review
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1.6 MB
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BMJ 2025
BMJ 2025
john-gásdal-karstensen-performance-measures-for.pdf
752 KB
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❤1
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674.3 KB
Canadian Adult Obesity Clinical Practice Guideline: Pharmacotherapy for Obesity 2025 clinical practice guideline update
✳️ NSAIDs use in IBD patients
▶️ Current ACG guidelines recommend viewing routine NSAID use with caution in Crohn's disease patients, noting they may exacerbate disease activity.
▶️ British Society of Gastroenterology guidelines (BSG) indicate short-term use is relatively safe when IBD is well-controlled, with approximately 20% relapse risk, and that selective COX-2 inhibitors show no difference from placebo in meta-analyses.
▶️ NSAIDs should be avoided in acute severe ulcerative colitis, as they have been associated with IBD-related hospitalizations and disease relapses.
▶️ When pain management is needed, consider acetaminophen as an alternative, though one study found it was also associated with active Crohn's disease (possibly as a marker of subclinical disease activity rather than causation).
▶️ If NSAIDs are necessary, consider selective COX-2 inhibitors or low-dose aspirin as potentially safer alternatives for short-term use in patients with well-controlled disease.
▶️ Current ACG guidelines recommend viewing routine NSAID use with caution in Crohn's disease patients, noting they may exacerbate disease activity.
▶️ British Society of Gastroenterology guidelines (BSG) indicate short-term use is relatively safe when IBD is well-controlled, with approximately 20% relapse risk, and that selective COX-2 inhibitors show no difference from placebo in meta-analyses.
▶️ NSAIDs should be avoided in acute severe ulcerative colitis, as they have been associated with IBD-related hospitalizations and disease relapses.
▶️ When pain management is needed, consider acetaminophen as an alternative, though one study found it was also associated with active Crohn's disease (possibly as a marker of subclinical disease activity rather than causation).
▶️ If NSAIDs are necessary, consider selective COX-2 inhibitors or low-dose aspirin as potentially safer alternatives for short-term use in patients with well-controlled disease.
❤3
ACG_clinical_guideline_update__preventive_care_in.15.pdf
661.7 KB
ACG Guideline Clinical Update : Preventive Care in Inflammatory Bowel Disease
July 2025
Functional dyspepsia 2026.pdf
3.9 MB
Functional dyspepsia
NEJM jan.2026