Frontiers in Computational Neuroscience
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Kohonen neural network and symbiotic-organism search algorithm for intrusion detection of network viruses

INTRODUCTION: The development of the Internet has made life much more convenient, but forms of network intrusion have become increasingly diversified and the threats to network security are becoming much more serious. Therefore, research into intrusion detection has become very important for network security.
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Sampling of environmental electromagnetic frequencies demonstrates the evolution of the nervous system toward social cognitive reflexes

The aim of this research is to help inspect the motion of cell life by applying electrical engineering scientific techniques to the cellular evolution of human neural networks. Using a mathematically rigorous theory of cellular biological progression, the hypothesis will demonstrate that cell life evolves toward increasing the organism's resonant energy transfer or "exposing points" with its natural environment. This increases the sampling points of electromagnetic radiation frequencies...
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Bayesian hierarchical models and prior elicitation for fitting psychometric functions

Our previous articles demonstrated how to analyze psychophysical data from a group of participants using generalized linear mixed models (GLMM) and two-level methods. The aim of this article is to revisit hierarchical models in a Bayesian framework. Bayesian models have been previously discussed for the analysis of psychometric functions although this approach is still seldom applied. The main advantage of using Bayesian models is that if the prior is informative, the uncertainty of the...
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Energy-based analog neural network framework

Over the past decade a body of work has emerged and shown the disruptive potential of neuromorphic systems across a broad range of studies, often combining novel machine learning models and nanotechnologies. Still, the scope of investigations often remains limited to simple problems since the process of building, training, and evaluating mixed-signal neural models is slow and laborious. In this paper, we introduce an open-source framework, called EBANA, that provides a unified, modularized, and...
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Editorial: Recent advances in EEG (non-invasive) based BCI applications

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A computational passage-of-time model of the cerebellar Purkinje cell in eyeblink conditioning

The cerebellar Purkinje cell controlling eyeblinks can learn, remember, and reproduce the interstimulus interval in a classical conditioning paradigm. Given temporally separated inputs, the cerebellar Purkinje cell learns to pause its tonic inhibition of a motor pathway with high temporal precision so that an overt blink occurs at the right time. Most models place the passage-of-time representation in upstream network effects. Yet, bypassing the upstream network and directly stimulating the...
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Predictive neuromodulation of cingulo-frontal neural dynamics in major depressive disorder using a brain-computer interface system: A simulation study

INTRODUCTION: Deep brain stimulation (DBS) is a promising therapy for treatment-resistant major depressive disorder (MDD). MDD involves the dysfunction of a brain network that can exhibit complex nonlinear neural dynamics in multiple frequency bands. However, current open-loop and responsive DBS methods cannot track the complex multiband neural dynamics in MDD, leading to imprecise regulation of symptoms, variable treatment effects among patients, and high battery power consumption.
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Approximate solutions to several classes of Volterra and Fredholm integral equations using the neural network algorithm based on the sine-cosine basis function and extreme learning machine

In this study, we investigate a new neural network method to solve Volterra and Fredholm integral equations based on the sine-cosine basis function and extreme learning machine (ELM) algorithm. Considering the ELM algorithm, sine-cosine basis functions, and several classes of integral equations, the improved model is designed. The novel neural network model consists of an input layer, a hidden layer, and an output layer, in which the hidden layer is eliminated by utilizing the sine-cosine basis...
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A survey of neurophysiological differentiation across mouse visual brain areas and timescales

Neurophysiological differentiation (ND), a measure of the number of distinct activity states that a neural population visits over a time interval, has been used as a correlate of meaningfulness or subjective perception of visual stimuli. ND has largely been studied in non-invasive human whole-brain recordings where spatial resolution is limited. However, it is likely that perception is supported by discrete neuronal populations rather than the whole brain. Therefore, here we use Neuropixels...
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Flexible intentions: An Active Inference theory

We present a normative computational theory of how the brain may support visually-guided goal-directed actions in dynamically changing environments. It extends the Active Inference theory of cortical processing according to which the brain maintains beliefs over the environmental state, and motor control signals try to fulfill the corresponding sensory predictions. We propose that the neural circuitry in the Posterior Parietal Cortex (PPC) compute flexible intentions-or motor plans from a belief...
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Leveraging conscious and nonconscious learning for efficient AI

Various interpretations of the literature detailing the neural basis of learning have in part led to disagreements concerning how consciousness arises. Further, artificial learning model design has suffered in replicating intelligence as it occurs in the human brain. Here, we present a novel learning model, which we term the "Recommendation Architecture (RA) Model" from prior theoretical works proposed by Coward, using a dual-learning approach featuring both consequence feedback and...
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New insights into binocular rivalry from the reconstruction of evolving percepts using model network dynamics

When the two eyes are presented with highly distinct stimuli, the resulting visual percept generally switches every few seconds between the two monocular images in an irregular fashion, giving rise to a phenomenon known as binocular rivalry. While a host of theoretical studies have explored potential mechanisms for binocular rivalry in the context of evoked model dynamics in response to simple stimuli, here we investigate binocular rivalry directly through complex stimulus reconstructions based...
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Retraction: Spiking correlation analysis of synchronous spikes evoked by acupuncture mechanical stimulus

This retracts the article DOI: 10.3389/fncom.2020.532193..
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Accurate few-shot object counting with Hough matching feature enhancement

INTRODUCTION: Given some exemplars, few-shot object counting aims to count the corresponding class objects in query images. However, when there are many target objects or background interference in the query image, some target objects may have occlusion and overlap, which causes a decrease in counting accuracy.
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Editorial: Computational methods for neuroimaging: Challenges and future trends

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An initial prediction and fine-tuning model based on improving GCN for 3D human motion prediction

Human motion prediction is one of the fundamental studies of computer vision. Much work based on deep learning has shown impressive performance for it in recent years. However, long-term prediction and human skeletal deformation are still challenging tasks for human motion prediction. For accurate prediction, this paper proposes a GCN-based two-stage prediction method. We train a prediction model in the first stage. Using multiple cascaded spatial attention graph convolution layers (SAGCL) to...
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Spike timing-dependent plasticity under imbalanced excitation and inhibition reduces the complexity of neural activity

Excitatory and inhibitory neurons are fundamental components of the brain, and healthy neural circuits are well balanced between excitation and inhibition (E/I balance). However, it is not clear how an E/I imbalance affects the self-organization of the network structure and function in general. In this study, we examined how locally altered E/I balance affects neural dynamics such as the connectivity by activity-dependent formation, the complexity (multiscale entropy) of neural activity, and...
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Dynamics of a model for the degradation mechanism of aggregated α-synuclein in Parkinson's disease

Accumulation of the misfolded synaptic protein α-synuclein (αSyn^(*)) is a hallmark of neurodegenerative disease in Parkinson's disease (PD). Recent studies suggest that the autophagy lysosome pathway (ALP) including both the Beclin1-associated and mTOR-signaling pathways is involved in the αSyn^(*) clearance mechanism. In this study, a mathematical model is proposed for the degradation of αSyn^(*) by ALP with the crosstalk element of mTOR. Using codimension-1 bifurcation analysis, the...
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neuroAIx-Framework: design of future neuroscience simulation systems exhibiting execution of the cortical microcircuit model 20× faster than biological real-time

INTRODUCTION: Research in the field of computational neuroscience relies on highly capable simulation platforms. With real-time capabilities surpassed for established models like the cortical microcircuit, it is time to conceive next-generation systems: neuroscience simulators providing significant acceleration, even for larger networks with natural density, biologically plausible multi-compartment models and the modeling of long-term and structural plasticity.
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Automated detection of myopic maculopathy using five-category models based on vision outlooker for visual recognition

CONCLUSION: The VOLO-D2 model accurately identified myopia-free macular lesions and four pathological myopia-related macular lesions with high sensitivity and specificity. It can be used in screening pathological myopic macular lesions and can help ophthalmologists and primary medical institution providers complete the initial screening diagnosis of patients.
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