Frontiers in Computational Neuroscience
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Reinforced liquid state machines-new training strategies for spiking neural networks based on reinforcements

INTRODUCTION: Feedback and reinforcement signals in the brain act as natures sophisticated teaching tools, guiding neural circuits to self-organization, adaptation, and the encoding of complex patterns. This study investigates the impact of two feedback mechanisms within a deep liquid state machine architecture designed for spiking neural networks.
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Regulation of sharp wave-ripples by cholecystokinin-expressing interneurons and parvalbumin-expressing basket cells in the hippocampal CA3 region

To explore the individual and interactive effects of the interneurons cholecystokinin-expressing interneurons (CCKs) and parvalbumin-expressing basket cells (BCs) on sharp wave-ripples (SWR) and the underlying mechanisms, we constructed a mathematical model of the hippocampal CA3 network. By modulating the activity of CCKs and BCs, it was verified that CCKs inhibit the generation of SWR, while the activity of BCs affects the occurrence of SWR. Additionally, it was postulated that CCKs exert an...
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Neuromorphic energy economics: toward biologically inspired and sustainable power market design

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iSeizdiag: toward the framework development of epileptic seizure detection for healthcare

INTRODUCTION: The seizure episodes result from abnormal and excessive electrical discharges by a group of brain cells. EEG framework-based signal acquisition is the real-time module that records the electrical discharges produced by the brain cells. The electrical discharges are amplified and appear as a graph on electroencephalogram systems. Different neurological disorders are represented as different waves on EEG records.
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Corrigendum: An enhanced pattern detection and segmentation of brain tumors in MRI images using deep learning technique

This corrects the article DOI: 10.3389/fncom.2024.1418280..
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Neural oscillation in low-rank SNNs: bridging network dynamics and cognitive function

Neural oscillation, particularly gamma oscillation, are fundamental to cognitive processes such as attention, perception, and decision-making. Experimental studies have shown that the phase of gamma oscillation modulates neuronal response selectivity, suggesting a direct link between oscillatory dynamics and cognition. However, there remains a lack of computational models that can systematically simulate and investigate this effect. To address this, we construct a low-rank spiking neural network...
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A new method for community-based intelligent screening of early Alzheimer's disease populations based on digital biomarkers of the writing process

CONCLUSION: Therefore, digital biomarkers based on the writing process can characterize and quantify the cognitive function of MCI due to AD populations at a fine-grained level, which is expected to be a new method for intelligent screening and early warning of early AD populations in a community-based physician-free setting.
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Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson's disease

INTRODUCTION: Emerging evidence suggests that different metabolic characteristics, particularly bioenergetic differences, between the synaptic terminal and soma may contribute to the selective vulnerability of dopaminergic neurons in patients with Parkinson's disease (PD).
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Enhancing medical image privacy in IoT with bit-plane level encryption using chaotic map

CONCLUSION: Extensive evaluations have proven that the designed scheme exhibits a high degree of resilience to attacks, making it particularly suitable for small IoT devices with limited processing power and memory.
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Multi-atlas ensemble graph neural network model for major depressive disorder detection using functional MRI data

Major depressive disorder (MDD) is one of the most common mental disorders, with significant impacts on many daily activities and quality of life. It stands as one of the most common mental disorders globally and ranks as the second leading cause of disability. The current diagnostic approach for MDD primarily relies on clinical observations and patient-reported symptoms, overlooking the diverse underlying causes and pathophysiological factors contributing to depression. Therefore, scientific...
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Reductionist modeling of calcium-dependent dynamics in recurrent neural networks

Mathematical analysis of biological neural networks, specifically inhibitory networks with all-to-all connections, is challenging due to their complexity and non-linearity. In examining the dynamics of individual neurons, many fast currents are involved solely in spike generation, while slower currents play a significant role in shaping a neuron's behavior. We propose a discrete map approach to analyze the behavior of inhibitory neurons that exhibit bursting modulated by slow calcium currents,...
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Analysis of argument structure constructions in a deep recurrent language model

Understanding how language and linguistic constructions are processed in the brain is a fundamental question in cognitive computational neuroscience. This study builds directly on our previous work analyzing Argument Structure Constructions (ASCs) in the BERT language model, extending the investigation to a simpler, brain-constrained architecture: a recurrent neural language model. Specifically, we explore the representation and processing of four ASCs-transitive, ditransitive, caused-motion,...
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CNN-BiLSTM and DC-IGN fusion model and piecewise exponential attenuation optimization: an innovative approach to improve EEG emotion recognition performance

EEG emotion recognition has important applications in human-computer interaction and mental health assessment, but existing models have limitations in capturing the complex spatial and temporal features of EEG signals. To overcome this problem, we propose an innovative model that combines CNN-BiLSTM and DC-IGN and fused both outputs for sentiment classification via a fully connected layer. In addition, we use a piecewise exponential decay strategy to optimize the training process. We conducted a...
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Generalizing location-centric variations to enhance contactless human activity recognition

Contactless Human Activity Recognition (HAR) has played a critical role in smart healthcare and elderly care homes to monitor patient behavior, detect falls or abnormal activities in real time. The effectiveness of non-invasive HAR is often hindered by location-centric variations in Channel State Information (CSI). These variations limit the ability of HAR models to generalize across new unseen cross-domain environments, for instance, a model trained in one location might not perform well in...
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