📌Glycogen storage diseases Part 2
#biochemistry

🔰 Cori
🔰 Anderson
🔰 Pompe
🔰 McArdle

🔘 Cardiomyopathy
🔘 Hypotonia
🔘 Exercise intolerance
🔘 Enlarged tongue
🔘Myoglobinuria(red urine)
🔘 Second wind phenomenon

#jonsharipov

🛑YouTube 👇
https://youtu.be/vHOmQeJw8RU?si=Uant_Knvra3RQ6Pj

📌 Lysosomal storage diseases

#biochemistry

🔰 Tay-Sachs
🔰 Fabry
🔰 Metachromatic leukodysrophy
🔰 Krabbe disease
🔰 Niemann Pick
🔰 Gaucher

🔘 Progressive neurodegeration
🔘 Developmental delay
🔘 Hiperreflexia or hiporeflexia
🔘 Cherry red spot on macula
🔘 Onion skin
🔘 Angiokeratomas
🔘 Hypohidrosis
🔘 Dementia
🔘 CN II atrophy
🔘 Hepatosplenomegaly
🔘 Osteoporosis
🔘 Bone crises
🔘 Necrosis
🔘 Other tissue cells damage

🛑 YouTube 👇
https://youtu.be/9v7bvGa5WB4?si=l6qNeo7RtWQlPB3S


@firstaidstep1

📌Fatty acid metabolism | Yog' kislota metabolizmi

Synthesis and Degradation

🔰 Citrate shuttle
🔰 Carnitine shuttle

🔘 Systemic 1° carnitine deficiency
🔘 Medium-chain Acyl-CoA dehydrogenase deficiency

🗣Steptaker: #jonsharipov

🛑YouTube 👇
https://www.youtube.com/embed/WIlFGpLTRjo

📌 Ketone bodies | Keton tanachalari
#biochemistry

〽️ Aceton
〽️ Acetoacetat
〽️ ɓ-hydroxybutyrate

🔘 Prolonged starvation
🔘 Diabetic ketoacidosis
🔘 Chronic alcohol ovurse
🔘 Fruty odor

🗣 #jon_sharipov

🛑 YouTube 👇
https://youtu.be/Rt0I_JYgS7s?si=dBM0Uov9MlsegEWE

📌 BILIRUBIN METABOLIZMI
#biochemistry

🔘 Grigler Najjar syndromes
🔘 Gilbert syndrome
🔘 Low levels of conjugation enzymes in newborn
🔘 Hepatic damage
🔘 Dubin Johnson syndrome
🔘 Rotor syndrome
🔘 Kernicterus

🗣 #jon_sharipov

@firstaidstep1

📌Bemor Bel-dumg'aza sohasini MRT qildirdi.

O'tgan yili belidagi og'riq, qotib qolishlar va oyoq sohasidagi kuchli og'riqlarga shikoyat qilib vrachga borgan. Vrach MRT tekshiruvini buyurgan, lekin belida kichkina protruziyadan tashqari tayinli o'zgarish chiqmagan. Shu narsa uchun lecheniya olgan lekin samara bermagan.

Bu yil xuddi shu shikoyatlari kuchayib menga murojiat qilgani uchun. Man ham tomografiya buyurdim, lekin o'sha holat.

So'rab surishtirish vaqtida bemor tomoq og'rig'idan va ko'p angina bo'lishidan shikoyat qildi. Kasbini so'radim, kalapocha pishiradigan joyda kalapocha tozalagan har kuni va uyi mol boqiladigan ferma oldida joylashgan.

Brutsilyoz va revmatizmdan shubha qildim undagi klinikani ko'rib va shular uchun qon topshirishini tayinladik va ikkala holatda ham rezultat musbat chiqdi. Davoladik va bemor hozir ahvolidan rozi.

Og'riqsiz yashash mazzada😁👍
#jon_sharipov

@firstaidstep1

📌Fasting and Fed state | Ochlik va To'qlik holati
#biochemistry

🔘Metabolic fuel use
🔘 Insulin affects
🔘 Glucagon/epinephrine affects
🔘 Starvation

🗣#jon_sharipov
@firstaidstep1

🛑 YouTube 👇
https://youtube.com/watch?v=IYCrqufeFlM&si=K2lH0gMq0G3WdJDx

📌 Lipoprotein metabolism Part 1

#biochemistry

🗣#jon_sharipov

🛑 YouTube 👇
https://youtu.be/tnFWTnBHROM?si=cmwAtnRnDhwewiy3

Ataxia(ataksiya) examination

Ataksiya bor yoki yo'q, bemorlarda tekshirish usullari. Albatta ko'ring kerak bo'ladi...


https://youtu.be/igHkor7AYUU?si=W5cat94NYUi1sIjb

📌USMLE STEP1 bo'yicha biochemistry barcha mavzulari tahlili.

🗣 Steptaker: #jon_sharipov


1] Yog'da va suvda eriydigan vitaminlar. Umumiy ma'lumot

2] Vitaminlar qo'shimcha qilish. Vitamin A

3] Vitamin B¹ va B²

4] Vitamin B³

5] Vitamin B⁵ B⁶ B⁷

6] Vitamin B⁹

7] Vitamin B¹²

8] Vitamin C

9] Vitamin va mineral absorption

10] Vitamin D

11] Vitamin E, K va Sink

12] KWASHIORKOR and MARASMUS

13] Ethanol metabolism Part 1

14] Ethanol metabolism Part 2

15] Enzyme terminology

16] Enzymes in metabolism

17] Glycolysis

18] Gluconeogenesis

19] Transports| Important enzymes

20] Regulation glycolysis and Gluconeogenesis with key enzymes

21] Piruvat dehydrogenase complex and deficiency

22] Pyruvate metabolism

23] TCA cycle(Krebs sikli)

24] Electron transport chain and oxidative phosphorilation

25] Pentose phosphate pathway

26] Glucose-6-phosphate dehydrogenase deficiency

27] Disorder o Fructose metabolism

28] Disorder of Galactose metabolism

29] Sorbitol

30] Lactase deficiency

31] Amino Acids

32] Urea cycle(mochevina sikli)

33] Hyperammonemia

34] Amino Acids derivatives| Catecholamine Synthesis| Tyrosine catabolism

35] Phenylketonuria

36] Maple syrup urine disease

37] Homocystinuria

38] Cystinuria and Organic acidemias

39] Glycogen metabolism by hormones and enzymes

40] Glycogen storage diseases Part 1

41] Glycogen storage diseases Part 2

42] Lysosomal storage diseases

43] Fatty acid metabolism| Yog' kislota metabolizmi

44] Ketone bodies

45] BILIRUBIN METABOLIZMI

46] Fasting and Fed state| Ochlik va To'qlik holati

47] Lipoprotein metabolism Part 1


Kanalga obuna bo’ling👇
@firstaidstep1

📌Ba'zi bir organlarning MRT tahlili

🗣Speaker: #jon_sharipov

1] Bosh miya. Kolloidniy kista

2] O't pufagi va o't yo'li. Tosh tiqilib qolishi

3] Bel-dumg'aza sohasi. 9 mm grija, lekin tayinli klinika yo'q. Nega?

4] Bel spinal blokadasi

5] Kichik chanoq sohasi. Bachadon miomasi

6] Bosh miya. Sfenoidit

7] Son suyak boshchasi. Osteonekroz

8] Bo'yin sohasi. Disk churrasi(grija)

9] Bel sohasi. 6mm grija va qiyshayish

10] Bel-dumg'aza sohasi. Og'riq sababi esa boshqa narsa

11] Tizza bo'g'imi MRT. Gonartoz 3-daraja.

12. Tizza bo'g'imi MRT. Xochsimon boylam uzilib ketgan

13. Paranasal sinuslar MRT. Gaymorit va sfenoidit

14. Tizza bo'g'imi MRT. Xochsimon boylam 2

15. Bel sohasi MRT. "Moshniy" disk churrasi

16. Bosh miya MRT. Ko'rish nervi nevriti.

17. Bachadon chanoq sohasi MRT. Chanoq sohasidagi og'riq sababi. Venoz dimlanish

18. Tizza bo'g'imi MRT. Son suyagi va katta boldir suyak yemirilishi

Kanalga do'stlaringizni taklif qiling👇
@firstaidstep1

📌N. RADIALIS nevropatiyasi.

Bemorga barmoqlarini yozishini aytganda u yozolmaydi. Panja mushaklari keyinchalik atrofiyaga ushrab ketadi.

📌Tizza bo'g'imi MRT.

Bemor zinadan yiqilishi hisobiga oldingi xochsimon boylam uzilib ketgan.

Bemordan so'rasa, harakatda cheklanish va oyog'i oldingi tomonga otilar ekan.

Zinadan tushayotganda ehtiyot bo'ling. Tizza hali ko'p kerak

@firstaidstep1

📌Paranasal sinuslar MRT

Bemorda ancha paytdan beri bosh og'rig'i qiynab kelgan.

Tekshiruvda aniqlandi:
🔘Gaymorit
🔘Sfenoidit

Bular ham boshga yaxshigina og'riq beradi.

@firstaidstep1

📌Tizza bo'g'imi MRT

Yana o'sha xochsimon boylam uzilib ketishi...

Akamiz Futbol o'ynab, oyog'iga jarohat bergan.

Futbol o'ynaydiganlarga tashab qo'yamiz😁...

@firstaidstep1

📌 Bel sohasi MRT

Belda "Moshniy" grija

Bemorni shikoyati: Belda kuchli og'riq, og'riq son, boldir va oyoq uchigacha tarqaladi. Sezgi ham pasaygan, oyoq mushaklarida atrofiya ham boshlangan. Bukulgandaku og'riq kuchayib jonimni oladi deydi. Siyish akti allaqachon buzilgan.

Unday holatda kutib o'tirilmaydi, darrov operatsiya qilish kerak.

@firstaidstep1

#Gastrointestinal

📌 Biliary structure | Biliar struktura


Ko'ramiz va share qilamiz
@firstaidstep1

🛑 YouTube 👇
https://youtu.be/6XgWeI_VbqY?si=HlhjQNSJGMLAaW-m