Forwarded from Med Squad 48 🎓 (Mawadda)
Clostridium.pdf
2.6 MB
شيت clostridium باحسن طريقة ممكن تقرو بيها 🩷 #microbiology
Forwarded from Med Squad 48 🎓 (Mawadda)
Untitled Notebook (4) (1).pdf
214.5 KB
ملخص للـ rickettsia
#microbiology
#microbiology
Forwarded from Med Squad 48 🎓 (Mawadda)
Non sporing forming gram positive Rods .pdf
1.7 MB
Forwarded from Med Squad 48 🎓 (Mawadda)
Aerobic rods.pdf
1.9 MB
Aerobic rods من اسموزس
ياريت يتعلموا يديرو شيتات هكي 😔
ياريت يتعلموا يديرو شيتات هكي 😔
Forwarded from Med Squad 48 🎓 (Mawadda)
cutaneous &subcut.mycoses.pdf
1.3 MB
ملخص شيت cutaneous &subcut.mycoses
#microbiology
#microbiology
Forwarded from Med Squad 48 🎓 (Hana'a Mohammed)
Actinomycetes.pdf
926.8 KB
ملخص شيت الactinomycetes ف صفحة
#microbiology
#microbiology
Forwarded from Med Squad 48 🎓 (Zahra Abdulsalam)
Gram (+)ve Bacteria.pdf
4.9 MB
جرايد A3 قرام بوزتف بكتيريا كاملة من شيتات الجامعة
#micro
#micro
Forwarded from Med Squad 48 🎓 (Zahra Abdulsalam)
non-Gram Stained.pdf
4.5 MB
جرايد A3 كاملات لل non-gram stained من شيت الجامعة
#micro
#micro
Forwarded from Med Squad 48 🎓 (Mawadda)
Third YearMicro-20230904192113.apkg
1.3 MB
فلاش كارد للجنرال على انكي ✨
[1] https://docs.ankidroid.org/manual.html
[2] https://apps.ankiweb.net/#download
[1] https://docs.ankidroid.org/manual.html
[2] https://apps.ankiweb.net/#download
Forwarded from Med Squad 48 🎓 (Mawadda)
Med Squad 48 🎓
https://apps.apple.com/app/id6443485322
هذا برنامج يفتح انكي على الابل ✨مجاني✨
Forwarded from Med Squad 48 🎓
Fungi generally .pdf
1.1 MB
General fungi ملخص للدكتور العماري نفس شيت جامعة بضبط مش ناقص شي🙏🏻
#microbiology
#microbiology
Forwarded from Med Squad 48 🎓 (Mawadda)
Microbiology Mind map1.pdf
3.1 MB
تجميعه رائعة للبكتريا مشاركه من احد الزملاء👌🏻🩷
#microbiology
#microbiology
❤1
Forwarded from Med Squad 48 🎓 (Mawadda)
Jawetz Mcq.pdf
4.1 MB
Forwarded from Med Squad 48 🎓 (Mawadda)
Forwarded from Med Squad 48 🎓 (Mawadda)
مايكرو.pdf
413.9 KB
Pdf التجميعات هذا رائع جدا ضروري تمرو عليه
Forwarded from Microbiology_lab48 🇵🇸
تجميعات مايكرو (by (K.O.E .pdf
2.3 MB
تجميعات مايكرو لميتهن ودرتهن
لكمPDF يا دفعة، فادني ما شاء الله ويا رب يفيدنكم🩷
ويا رب يوفقنا ولربيع الطب كلنا💚✨
#تجميعة_مايكرو🔵
لكمPDF يا دفعة، فادني ما شاء الله ويا رب يفيدنكم🩷
ويا رب يوفقنا ولربيع الطب كلنا💚✨
#تجميعة_مايكرو🔵
💯3❤1
Forwarded from Enas Alzway
🐞 (( ملخص Antibiotics))🐞
Spectrum of activity :-
☆_Narrow spectrum :- 🐊
Kill either gram + or -
Broad spectrum :- kill both +/-
☆_Mechanism of action :- 🐝
1)_ inhibtion of Cell wall :-
عائلة B.lactam
Charecters :- 🐋
Possess B.lactam ring
Bactericidal
Act by inhibition peptidoglycan synthesis.
واهمهن 》》Penicillin اللى اكتشفه الكسندر فلمنج
Alexander fleming in 1929
Mode of action :- 🐌
Bind to penicillin binding proteins PBPs.
Mechanism of resistance in penicillin :-
☆,Modification or 1)_ inactivation by B.lactamase ( by transposones Tn552 & often by plasmid )
الاهم》》Transposon
or by
2)_ alteration target site. By one of 3
☆_Chromosomal mutation ( Mec A) on staphylococus cassete chromosme SCC 》lead to PBP 2 a formation ..
☆_transposons
☆_plasmide
Other B.lactam :- 🐌
2_Monobactams :-limited to aerobic gram negative bacilli
3_Carbapenem :- broad spectrum
4_Cephalosporins :- 5 generation
5_Glycopeptide :- include Vancomycin
Most imp against 》》MRSA. (MCQ)
Mechanism of resistance in VRSA 🐞
☆altered target site .(MCQ)
Mechanism in VISA ( vancomycin intermediateS.Aureus ) by altered cell wall biosynthesis ..
________________
2)_Cell membrane interuption :- 🐍
A)_polymyxin:- = P (bind to phospholipid)
Effective against gram negative and psudomonas ..
_________
3)_inhibit protein synthesis :- 🐞
Bind to ribosomal subunit ..
If reversible 》》Bacteriostatic 🐞
If irreversible 》Bactericidal .🐍
☆_Aminoglycoside & Tetracycline bind to 30 subunit or Ribosome .
☆_Macrolid & Chloramphenicol (50 S )
All bacteriostatic except Aminoglycoside
Ex :-
A)_Aminoglycoside :- 🐞
☆_Bactericidal .
As ...Gentamycin ..Tobramycin ..Amikacin
Effective only against (Aerobic ) MCQ
B)_Tetracyclin :- 🐞
☆. Bacteriostatic .
☆.T = T ( teratogenic )
▪☆.Contraindication in children below 8 y b/c affect bone and teeth development
Imp for Chlamydia & Rickettsia
Mechanism of resistance :- By efflux pump (MCQ)🐌
C)_Macrolides :-🐌
Bacteriostatic ،broad spectrum.
As Erythromycin , Clindamycin
Against G.+ and intracellular parasite .
Mode of resistance :-
☆_Efflux.... as tetracyclin
☆_Alteration of 23 S ...rRNA of 50 S
____________
D)_Chloramphenicol :- 🐍
Bacteriostatic ، Broad spectrum .
Bone marrow supressor as a side effect .
_______________
4)_Inhibition of neuclic acid :-
A)_Quinolone :- (Bactericidal)
Inhibit DNA gyrase(topoisomerase IV)
As ciprofloxacilin &nalidixic acid
B)_Rifampicin :-inhibit RNA
polymerase(R= R )
C)_Metronidazole :-
Damage DNA and block synthesis
Effective against anaerobe only
4)_Sulphonamide :-
Inhibit folate synthesis as Trimethoprim by inhibit (PABA ) para amino benzoic acid ..
وتجى ام سكيو يقولك من يشتغل على PABA
__________
Spectrum of activity :-
☆_Narrow spectrum :- 🐊
Kill either gram + or -
Broad spectrum :- kill both +/-
☆_Mechanism of action :- 🐝
1)_ inhibtion of Cell wall :-
عائلة B.lactam
Charecters :- 🐋
Possess B.lactam ring
Bactericidal
Act by inhibition peptidoglycan synthesis.
واهمهن 》》Penicillin اللى اكتشفه الكسندر فلمنج
Alexander fleming in 1929
Mode of action :- 🐌
Bind to penicillin binding proteins PBPs.
Mechanism of resistance in penicillin :-
☆,Modification or 1)_ inactivation by B.lactamase ( by transposones Tn552 & often by plasmid )
الاهم》》Transposon
or by
2)_ alteration target site. By one of 3
☆_Chromosomal mutation ( Mec A) on staphylococus cassete chromosme SCC 》lead to PBP 2 a formation ..
☆_transposons
☆_plasmide
Other B.lactam :- 🐌
2_Monobactams :-limited to aerobic gram negative bacilli
3_Carbapenem :- broad spectrum
4_Cephalosporins :- 5 generation
5_Glycopeptide :- include Vancomycin
Most imp against 》》MRSA. (MCQ)
Mechanism of resistance in VRSA 🐞
☆altered target site .(MCQ)
Mechanism in VISA ( vancomycin intermediateS.Aureus ) by altered cell wall biosynthesis ..
________________
2)_Cell membrane interuption :- 🐍
A)_polymyxin:- = P (bind to phospholipid)
Effective against gram negative and psudomonas ..
_________
3)_inhibit protein synthesis :- 🐞
Bind to ribosomal subunit ..
If reversible 》》Bacteriostatic 🐞
If irreversible 》Bactericidal .🐍
☆_Aminoglycoside & Tetracycline bind to 30 subunit or Ribosome .
☆_Macrolid & Chloramphenicol (50 S )
All bacteriostatic except Aminoglycoside
Ex :-
A)_Aminoglycoside :- 🐞
☆_Bactericidal .
As ...Gentamycin ..Tobramycin ..Amikacin
Effective only against (Aerobic ) MCQ
B)_Tetracyclin :- 🐞
☆. Bacteriostatic .
☆.T = T ( teratogenic )
▪☆.Contraindication in children below 8 y b/c affect bone and teeth development
Imp for Chlamydia & Rickettsia
Mechanism of resistance :- By efflux pump (MCQ)🐌
C)_Macrolides :-🐌
Bacteriostatic ،broad spectrum.
As Erythromycin , Clindamycin
Against G.+ and intracellular parasite .
Mode of resistance :-
☆_Efflux.... as tetracyclin
☆_Alteration of 23 S ...rRNA of 50 S
____________
D)_Chloramphenicol :- 🐍
Bacteriostatic ، Broad spectrum .
Bone marrow supressor as a side effect .
_______________
4)_Inhibition of neuclic acid :-
A)_Quinolone :- (Bactericidal)
Inhibit DNA gyrase(topoisomerase IV)
As ciprofloxacilin &nalidixic acid
B)_Rifampicin :-inhibit RNA
polymerase(R= R )
C)_Metronidazole :-
Damage DNA and block synthesis
Effective against anaerobe only
4)_Sulphonamide :-
Inhibit folate synthesis as Trimethoprim by inhibit (PABA ) para amino benzoic acid ..
وتجى ام سكيو يقولك من يشتغل على PABA
__________
❤1👍1