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1. Regarding tumor immunity, which one of the following is the most accurate?
(A) Both cytotoxic T cells and cytotoxic antibodies attack human cancer cells.
(B) An elevated level of alpha-fetoprotein is a marker for carcinoma of the lung.
(C) A declining level of carcinoembryonic antigen (CEA) is an indication that the
patient’s colon cancer has recurred.
(D) Cancer cells induced by chemicals have new antigens on the surface but
cancer cells induced by viruses do not.
(E) Natural killer (NK) cells do not participate in the cell-mediated response to
cancer cells because they do not have an antigen-specific receptor on their
surface.
(A) Both cytotoxic T cells and cytotoxic antibodies attack human cancer cells.
(B) An elevated level of alpha-fetoprotein is a marker for carcinoma of the lung.
(C) A declining level of carcinoembryonic antigen (CEA) is an indication that the
patient’s colon cancer has recurred.
(D) Cancer cells induced by chemicals have new antigens on the surface but
cancer cells induced by viruses do not.
(E) Natural killer (NK) cells do not participate in the cell-mediated response to
cancer cells because they do not have an antigen-specific receptor on their
surface.
Forwarded from ㅤHAMD ALZWAWY
The two most common types of viral vaccines are killed vaccines and live-attenuated vaceines. Regarding these vaccines, which one of the following statements is the MOST accurate?
Anonymous Quiz
55%
Killed vaccines are safer to give to immune-compromised patients than are live attenuated vaccines,
13%
Killed vaccines induce a longer-lasting response than do live,attenuated, vaccines.
12%
Killed vaccines are no longer used in this country because they do not induce scoretory Ig A
3%
Killed vaccines induce a broader range of immune responses than do live attenuated vaccines
18%
All the above
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Regarding the primary and secondary antibody responses, whichone of the following statements is MOST accurate?
Anonymous Quiz
64%
The amount of IgG made in the secondary response greater than the amount madein the primary response
17%
The IgM made in the primary response is made primarily by memory b cells
8%
The lag phase is shorter in the primary response than in the secondary response
6%
In the primary response, memory B cells are produced, but memory T cells not
6%
Antigen must be processed and presented in the primary response but not in the secondary response.
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Antigen-presenting cells that activate helper T cells must express which one of the following on their surfaces
Anonymous Quiz
8%
Class III MHC antigens
8%
IgE
6%
Gamma interferon
18%
Class I MHC antigens
60%
Class II MHC antigens
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Which one of the following doesnot contain c3b
Anonymous Quiz
18%
Alternative-pathway C3 convertase
7%
Classic-pathway C5 convertasc
20%
Alternative-pathway C5 convertase
34%
Classic-pathway C3 convertase
20%
All of the above
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Ireversible (permanent) IgG binding to neutrophils cells is mediated by:
Anonymous Quiz
14%
Fc-dependent cellular homing mechanisms.
15%
Sensitization of Mast cells and basophils
49%
Fc receptors specific for IgG.
12%
ICAM's
11%
nune of the above
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25) Innate host defense mechansims are critical to the protection of the body because
Anonymous Quiz
13%
utilize precommited angiten presenting cells that have already been induced by other immune response
15%
The antibodies derived from the innate response are critical to neutralize bacteria toxins
8%
They aer hgihyl specific for the inivadnig pahtogens that avodi PAMPS receptor recognition
27%
They provide immediate continuous protection in the albsense of specific immune response.
37%
B &D
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2. All are true with regard to interferons except :
Anonymous Quiz
41%
They are produced by B lymphocytes
12%
IFN alpha are produced by cells infected with virus
16%
C. IFNy increases MCH classI and lI expression in antigen presenting cell
21%
IFNß are produced by fibroblasts.
10%
They have anti-tumouractivity...
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Forwarded from ㅤHAMD ALZWAWY
Anaphylactic reaction involves all excepts:
Anonymous Quiz
72%
Langhan's giant cells.
2%
histamine
13%
basophil
6%
mast cells.
7%
IgE
Forwarded from ㅤHAMD ALZWAWY
Secretory Ig A function include all follownig except
Anonymous Quiz
4%
is a dimer responsible for mucosal immunity.
49%
is not found in the piasma.
18%
is assembled in the lymph nodes.
22%
It is transported across themucosal epithelium bound to a receptor complex.
7%
restricts bacterial adhesion to mucosal membrane.
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Regarding the complement system all true except:
Anonymous Quiz
14%
The classical pathway is activated by antibody-antigen complexes.
16%
The alternative pathway is activated by the cell wall of bacteria.
25%
C5b-9 attacks the MHC proteins in the cell membrane.
27%
Deposition of C3b on the bacterial cell wall causes phagocytosis by leucocytes
17%
Activation causes recruitment of inflammatory cells.
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Humoral immunity can be acquired passively by
Anonymous Quiz
13%
catching a virus from a friend by shaking hands.
30%
receiving a vaccine of influenza virus grown in eggs.
36%
receiving serum from someone who has recovered from an infection.
20%
receiving leukocytes from an immune family member.
2%
sharing a soda with someone who has a cold.
Forwarded from ㅤHAMD ALZWAWY
For specific antigen recognition by T cells,
Anonymous Quiz
27%
antigen is bound by a T cell membrane antibody.
32%
processing of antigen help epitope recognition.
12%
MHC molecules are not required.
20%
antigen exposure during T cell maturation is required
10%
None of the above
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The most frequently diagnosed form of specific primary immunodeficiency
Anonymous Quiz
12%
Severe combined immunodeficiency
34%
X-linked agammaglobulinaemia
14%
Chronic granulomatous disease
26%
Selective IgA deficiency
14%
Di George anomaly
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Which one is the commonest form of Severe Combined Immune Deficiencies SCIDs|?
Anonymous Quiz
36%
Interleukin receptor common gamma chain deficiency
11%
IgA deficiency
11%
IRAK-4 deficiency
30%
RAGI/RAG2 deficiency
11%
Di George syndrome
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Which one of the following is most relevant to transient hypogammaglobulinaemia of infancy
Anonymous Quiz
38%
Is more pronounced in premature babies.
11%
Occurs at one months of age.
21%
Is due to placental absorption of IgG.
18%
Is linked with autoimmune disease in later life.
13%
Involves only the IgA immunoglobulin class.
Forwarded from ㅤHAMD ALZWAWY
Which one of the following is the primary defect in chronic granulomatous disease?
Anonymous Quiz
22%
Neutrophil production in the bone marrow.
10%
Neutrophil chemotaxis.
38%
Neutrophil intracellular killing of organisms.
13%
Opsonization
17%
Cytotoxic T-cell activity.
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Which one of the following statements concerning XLA) X linked agammaglobullinemia is
CORRECT?
CORRECT?
Anonymous Quiz
17%
XLA presents immediately after birth.
19%
It is a disease found in equal numbers of boys and girls
32%
Patients with XIA present with recurrent severe bacterial and fungal infections
28%
Patients usually have pan-hypogammaglobulinacmia
4%
Patients have normal numbers of plasma cells in the gut.
Forwarded from ㅤHAMD ALZWAWY
Which one of the following autoimmune diseases involves only Type II hypersensitivity?
Anonymous Quiz
18%
Rheumatoid arthritis
62%
Myasthenia gravis
6%
Contact dermatitis
6%
Mixed cryoglobulinacmia
6%
Anaphylactic reactions