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3. As part of the innate immune response, which cells participate
in phagocytosis?
in phagocytosis?
Anonymous Quiz
11%
(A) Macrophages and mast cells
8%
B) Macrophages and plasma cells
15%
C) NK cells and neutrophils
63%
D) Macrophages and neutrophils
3%
E) T cells and mast cells
❤1👏1
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4. The immunoglobulin class most frequently responsible for
inhibition of bacteria on mucosal surfaces is:
inhibition of bacteria on mucosal surfaces is:
Anonymous Quiz
16%
A) IgG
8%
B) IgM
65%
C) IgA
9%
C) IgE
2%
E) IgD
👏1
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5. Which of the following properties is associated with MHC?
Anonymous Quiz
66%
A) Binds peptide antigen and presents it to T cells
4%
B) Binds virus particles and neutralizes the virus
8%
C) Binds LPS and interferes with bacterial phagocytosis
6%
C) Binds LPS and interferes with bacterial phagocytosis
15%
D) Binds self-antigens and presents them to NK cells
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6. Which of the following items regarding T cells located in lymph
node follicles participate in B cell help with isotype switching
and antibody production?
node follicles participate in B cell help with isotype switching
and antibody production?
Anonymous Quiz
27%
A) Th1 cells
41%
B) Th2 cells
11%
C) Th17 cells
19%
D) T reg
2%
(E) Tfh cell
❤1
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7. Which of the following functional properties are not associated
with IFN-gamma?
with IFN-gamma?
Anonymous Quiz
20%
A) Induces production of other pro-inflammatory cytokines
20%
B) Anti-proliferative activity
25%
C) Anti-viral activity
35%
D) Triggers plasma cell formation and antibody production
❤1👍1
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8. Which of the following cytokines can inhibit or downregulate
the immune response?
the immune response?
Anonymous Quiz
35%
A) IFN-beta and IL-10
33%
B) IFN-gamma and IL-10
13%
C) IFN-beta and IL-2
19%
D) IL-17 and IL-
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9. The initial step in antibody formation begins with the binding
of antigen to the B cell surface immunoglobulin via:
of antigen to the B cell surface immunoglobulin via:
Anonymous Quiz
21%
(A) MHC class I molecule
36%
B) MHC class II molecule
39%
C) B cell recepter (BCR)
4%
(D) KIRS
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10. Which of the cytokines attracts neutrophils and inhibit
bacteria?
bacteria?
Anonymous Quiz
26%
(A) IFN-gamma (B) IL-8 (CXCL8)
31%
B) IL-8 (CXCL8)
15%
C) IL-2
18%
D) IL-6
10%
(E) TGF-β
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11. MHC class I molecules are critically important in what immu-
nologic process?
nologic process?
Anonymous Quiz
5%
A) IgE-mediated histamine release
9%
(B) Phagocytosis
10%
C) Immunoglobulin class switching
73%
D) CD8+ T-cell cytotoxici
3%
E) Opsonization
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12. The host response to the interaction of a pathogen with its specific
TLR generates which of the following?
TLR generates which of the following?
Anonymous Quiz
5%
(A) IgG production
35%
B) Cell activation and production of cytokines and chemokines
13%
C) Immunoglobulin class switching
16%
D) Phagocytosis (E) Presentation of
31%
E) Presentation of pathogen to helper T cell
❤1
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13. The interaction of two IgG molecules binding to antigen followed
by the binding of C1 to the Fc portion of the antibody
results in which of the following?
by the binding of C1 to the Fc portion of the antibody
results in which of the following?
Anonymous Quiz
8%
(A) Initiation of antigen presentation
73%
B) Initiation of classical complement pathway
12%
(C) Initiation of alternative complement pathway
7%
D) Initiation of the mannose-binding lectin-binding comple- ment pathway
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14. Which genetic mechanism generates antibodies of the same
specificity but different immunoglobulin classes?
specificity but different immunoglobulin classes?
Anonymous Quiz
15%
A) V gene segment recombination
54%
B) Class switching
15%
C) Somatic hypermutation
16%
D) Junctional variability due to imprecise V, D, and Joining
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15. Which major antibody molecule has the ability to cross the placenta
Anonymous Quiz
86%
(A) IgG
3%
(B) IgA
9%
C) IgM
0%
D) IgE
2%
E) IgD
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16. A man in his twenties presents in the emergency room with
shortness of breath and fatigue. He is also very pale. Two days
earlier he was given penicillin for an infection. He had penicillin
previously without problems and stated that he had “no
allergy” to penicillin. Laboratory testing shows that antibodies
to penicillin are present in the patient’s serum and that he is
breaking down his own red blood cells. He is diagnosed with
immune hemolytic anemia
shortness of breath and fatigue. He is also very pale. Two days
earlier he was given penicillin for an infection. He had penicillin
previously without problems and stated that he had “no
allergy” to penicillin. Laboratory testing shows that antibodies
to penicillin are present in the patient’s serum and that he is
breaking down his own red blood cells. He is diagnosed with
immune hemolytic anemia
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كل مايخص طلاب الطب💜
16. A man in his twenties presents in the emergency room with shortness of breath and fatigue. He is also very pale. Two days earlier he was given penicillin for an infection. He had penicillin previously without problems and stated that he had “no allergy”…
The patient has which type of hypersensitivity reaction?
Anonymous Quiz
38%
(A) Type I
44%
(B) Type II
13%
(C) Type III
5%
(D) Type IV (DTH)
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17. Which one of the following cell types expresses receptors for
IgE on its cell surface that stimulate the cell to mount a response
to parasites such as worms?
IgE on its cell surface that stimulate the cell to mount a response
to parasites such as worms?
Anonymous Quiz
13%
(A) T cells
8%
(B) B cells
10%
(C) NK cells
68%
(D) Mast cells
2%
(E) Dendritic cells
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18. IgE-mediated histamine release is classified as what type of
hypersensitivity reaction?
hypersensitivity reaction?
Anonymous Quiz
68%
(A) Type I
14%
(B) Type II
13%
(C) Type III
5%
(D) Type IV
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19. Which two cytokines play an important role in attracting neutrophils
to the site of an infection?
to the site of an infection?
Anonymous Quiz
16%
(A) IFN-alpha and IFN-gamma
62%
(B) IL-8 and IL-17
9%
(C) IL-2 and IL-4
13%
(D) IL-6 and IL-12
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20. Which one of the following laboratory assays is considered to be
an in vitro counterpart of the type IV hypersensitivity reactions
seen in the TB skin test?
an in vitro counterpart of the type IV hypersensitivity reactions
seen in the TB skin test?
Anonymous Quiz
25%
(A) Immunoblot for TB antigen
8%
(B) EIA analysis of sera from TB patient
39%
(C) Immunofluorescence assay for TB antibody
27%
(D) IFN-gamma production by white blood cell (WBC) treated with TB antigen
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21. Which of the following laboratory assays can be used to detect
the number and types of immune cells in the peripheral blood?
the number and types of immune cells in the peripheral blood?
Anonymous Quiz
37%
(A) Immunofixation electrophoresis
13%
(B) EIA
40%
(C) Flow cytometry
10%
(D) Immunoblot
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22. PD-1 and CTLA-4 are targets for cancer immune therapy and
are both expressed on what cell type:
are both expressed on what cell type:
Anonymous Quiz
7%
(A) Plasma cells
12%
(B) Mast cells
3%
(C) Neutrophils
27%
(D) Activated T cells
52%
E) Tumor cells