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A labyrinth of ideas,
A diary of curiosities

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One key remedy from the East was opium, largely imported from Turkey. It had been in use in Egypt in the second millennium BC, and Avicenna إبن سينا called it 'the most powerful of stupefacients'. Ever the queen of drugs, it was profusely used in western medicine from the sixteenth century, and Thomas Sydenham (1624 - 89) later proclaimed that 'among the remedies which it has pleased the Almighty God to give to man to relieve his sufferings, none is so universal and so efficacious as opium.' It seemed the wonder drug; not just a pain-deadener, it also stopped dysentery and relieved respiratory disorders.

- The Greatest Benefit To Mankind
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Poppy plant نبات الخشخاش
نبات الخشخاش هو اللي يستخلصون منه الأفيون Opium. الأفيون يحتوي على مركّب فعال هو المورفين Morphine اللي يشتغل على مستقبلات الأفيون اللي بجسمك ويتسبب بهواي تأثيرات من ضمنها تقليل الشعور بالألم، تقليل حركة الأمعاء، وشغلة أخيرة مهمة هي أنّه يشتغل على مراكز التنفس والكحة cough center بالدماغ ويمنع الكحة أو يقللها، بس بجرعات عالية ممكن يطفي مراكز التنفس أصلًا (بالإضافة للخدر وفقدان الوعي) فتتوقف عن التنفس وتموت بالإختناق.
Morphine is the active molecule.
While codeine is the prodrug of morphine (3-methylmorphine).

Dextromethorphan is from the same family but mainly works on the cough center, so you can find it everywhere in cough syrups.

Heroin is a derived compound of morphine thag was originally thought to be more potent (that's true) but less addictive (that's wrong) than morphine.
Morphine now is mainly used as a painkiller in cases of severe pain, and administered under strict supervision.
Codeine is used as a painkiller too, and rarely as a cough suppressant (it can be addictive).
Dextromethorphan is mainly a cough suppressant.
While Heroin, as far as I know, does not have medical uses.
الفكرة هي أنّ كلهن يسببن الخدر بدرجة أو بأُخرى، بس بنفس الوقت كلهن يأثرن على الـ cough center

لهذا مدمني هاي المواد يكونون تحت خطر الإختناق، لأن دماغهم يبطل يرسل الإشارة للرئة حتى تشتغل ويتنفسون.
House MD's vicodin is a hydrocodone¹/paracetamol

¹semi-synthetic opiate.
Insomnia does really fuck you up
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Insomnia does really fuck you up
Nah ur already fucked up
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Nah ur already fucked up
That's true ngl
But the fuck up gets even worse
La Fornarina,
By Raphael
Sunset at Ivry,
By Armand Guillaumin
Surgery was seen as a skilled craft: ‘A surgeon should have three diverse properties in his person’ judged John Halle (1529 - 68), ‘that is to say, a heart as the heart of a lion, his eye like the eyes of an hawk, and his hands as the hands of a woman.’

- The Greatest Benefit To Mankind, by Ray Porter
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