Episteme turns hypotheses into tokenized prediction markets where truth is rewarded. Built on Humanode so fairness is the foundation.

@Episteme_ac testnet is live → https://epistemesci.substack.com/p/announcing-the-eidolon-testnet

Apply for whitelist → https://www.episteme.ac/whitelist

Episteme’s vision for DeScAI (the convergence of DeSci & AI) is now peer-reviewed and live in Frontiers in Blockchain.

📖 Read here: https://doi.org/10.3389/fbloc.2025.1657050

In this article, our co-founder Sasha Shilina introduces DeScAI, a five-stratum framework for a recursive, self-verifying scientific system. By weaving together decentralized ledgers, incentive protocols, and AI-driven scientific agents, DeScAI proposes a future where:

🟡Hypotheses move to verification with radically reduced latency
🟡Epistemic pluralism becomes structurally supported
🟡Trust is cryptographically auditable

DeScAI shows that this future isn’t speculative — the building blocks already exist. What’s left is orchestration.

📒 Futarchy for Science

A new paper by researchers from Bio Protocol and Episteme is now published in Frontiers in Blockchain.
👉 https://doi.org/10.3389/fbloc.2025.1650188

What if science governed itself?
This study explores futarchy, where communities vote on values but bet on beliefs, applied to DeSci.

Using governance data from 13 science DAOs and a counterfactual futarchy simulation on real proposals, the paper finds that futarchy’s predicted outcomes aligned perfectly with the decisions DAO members actually made. In other words, DeSci is already behaving as if it’s futarchic, it just needs the tools to make that logic explicit.

Got a hypothesis that deserves a market?

Episteme’s submission form is live: send us your best testable claims.

We’ll curate, list, and let DeScAI price the future.
🔗 https://docs.google.com/forms/d/e/1FAIpQLSeFbAIko2aJsp_S99RXphjES2VVUFRxTd-ZxDmms7EFZOdCRw/viewform

Nya~ Prediction season doesn’t end. It crystallizes ❄️