Alzheimer’s may be linked to gum bacteria, new research shows.

Scientists have repeatedly found Porphyromonas gingivalis—the chief bacterium that causes periodontitis—inside the brains of people who died with Alzheimer’s.

When researchers deliberately infected mice with this oral bacterium, the animals rapidly developed key Alzheimer’s pathology, including the buildup of amyloid-beta plaques.

Perhaps most alarming, the bacteria’s toxic enzymes have been detected in the brains of people showing early Alzheimer’s changes years before memory loss or other symptoms appear, suggesting the infection may quietly initiate damage long in advance.

These discoveries have sparked serious interest in new treatment approaches. An experimental drug called COR388 (from the company Cortexyme) has already succeeded in lowering both bacterial load and amyloid-beta levels in preclinical models. Although large human trials are still needed, the evidence is mounting that at least some cases of Alzheimer’s may have an infectious trigger rather than being purely degenerative.

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You never wanted dry texting with women.

What you actually wanted is sex.

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The aftermath of the 1.2 million square foot paper products warehouse in Ontario, California that was set on fire by a disgruntled employee

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We had it all

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Guy wanted to douse himself in flammable liquid and burn… but the firemen had other plans

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Income tax by state.

California has the highest state income tax at 13.3%

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The 2025 tariffs have had ~94% pass-through (!) and the actual rates of them have only been about half as large as the announced ones

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Market breadth is improving:

~65% of stocks in the Nasdaq 100 ETF, $QQQ, are now trading above their 10-day moving average, near the highest since early December.

This percentage has surged +40 points in just 5 trading sessions, the largest increase since November.

By comparison, in the 2nd week of March, just 12% of stocks traded above their 10-day moving average, the lowest in at least 6 months.

In the past, the Nasdaq 100 has been higher 80% of the time over the next 12 months after such a sharp reversal.

Furthermore, over 70% of stocks in the S&P 500 and the Dow Jones Industrial Average are also trading above their 10-day moving average.

The market is setting up for a historic recovery.

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In Washington D.C., the cherry blossoms are blooming earlier and earlier.

This replicates what's happened in Japan, which makes sense given that it's driven by the same global warming.

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