NOW - Trump on Iran: "So now we may have to take it a step further, or we may not. Maybe we're going to make a deal... you're going to be finding out over the next probably 10 days."

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Researchers from Spain and China achieved a significant advance in Alzheimer’s research by developing nanoparticles that clear toxic brain plaque, a key contributor to the disease, and reverse memory loss in mice.

Published in Signal Transduction and Targeted Therapy, the study showed that three injections of these nanoparticles reduced harmful amyloid beta proteins in the brain by up to 60% within an hour.Remarkably, mice with severe memory and cognitive impairments regained normal behavior within six months.

The treatment not only cleared brain plaque but also repaired the blood-brain barrier (BBB), which protects the brain and clears waste but becomes impaired in Alzheimer’s, allowing harmful substances to accumulate.

Acting as a “supramolecular drug,” the nanoparticles restore the brain’s natural waste-clearing system by activating the LRP1 protein. This improved blood flow, reduced inflammation, and supported brain healing. While still in animal testing, this approach suggests a new path for Alzheimer’s treatment, focusing on enhancing the body’s defenses rather than just targeting toxic proteins.

If successful in humans, it could transform the fight against Alzheimer’s and other neurodegenerative diseases.

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Haters will say this is AI

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In the 1500s, French jester Triboulet was sentenced to death for slapping King Francis I on the behind. When asked to apologize, he insulted the Queen, making his sentence final. Offered a choice of how to die, he replied, "I choose to die of old age." The King spared his life

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FOLLOWUP (0.84, took 0.3s):

I had a good talk with ZachWitkoff and WatcherChase about $WLFI yesterday, to better understand their vision and where they see worldlibertyfi going.

I met many teams in crypto in my life, often with a short-term ‘plan’, and it’s fine for you to invest in these if you’re willing to take a lot of risk. Because these projects more often than not fail quickly.

But the $WLFI team truly has a long-term vision about where they want to bring this project in X years from now. As a community, we have to adapt our time horizon to that of the team.

They are working on lots of different things - and yes, also for the community. I had a genuinely good feeling and vibe with them.

I’m here for the long-term. And that vision and belief had a great boost yesterday.

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BREAKING: Post Falls City Council votes to end Juneteenth & restore Columbus Day

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Canadians won’t join the military to support a regime that hates them, so they’re planning to fill the ranks with foreign mercenaries to do their bidding.

These actions are a threat to both Canada’s national and domestic security.

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Crypto outflows remain strong:

Crypto funds posted -$173 million in outflows last week, marking their 4th consecutive weekly withdrawal.

This brings 4-week cumulative outflows to -$3.74 billion.

Bitcoin led the selling with -$133 million in outflows last week, while Ethereum saw -$85 million.

Crypto funds have now seen withdrawals in 11 out of the last 16 weeks.

Since October 2025, -$8.5 billion has flowed out of US-listed spot Bitcoin ETFs alone.

Sentiment is reaching extreme bearish levels.

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Instant Karma

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BREAKING - A Pennsylvania principal, Daniel Weber of Wilson High School, is receiving widespread recognition after shutting down an anti-ICE walkout at his school by threatening suspension for all students involved

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Former Meta AI researcher Yann LeCun says that the future generation of AI talent will come from Africa and India

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New Mexico probes allegation of bodies buried near Epstein ranch — Reuters

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Trump: "Now is the time for Iran to join us on a path that will complete what we're doing. If they join us, that'll be great. If they don't join us, that'll be great too — but it'll be a very different path. They cannot continue to threaten the stability of the entire region."

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Market not so sure: odds Khamanei out by year-end a coin toss

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A whale with $22 million in profits has just opened a $66.16 million $BTC long with 3x leverage.

Liquidation Price: $43,785

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How bad do things need to get before Germans and the rest of Europe wake up?

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