Forwarded from Scrub notes 🩺
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Patho| ملاحظات المحاضرة السابعة
❗آخر محاضرة في cell injury❗:
Part1:
🔴Hemosiderin➡️Prussian blue iron stain:➡️the stain demonstrates the blue granules of hemosiderin in hepatocytes and Kupffer cells.❗important❗.
🔴Hemohidrosis does not involve tissue damage, unlike hematosis, which involves tissue damage.
🔴Hemochromatosis (H&E, Prussian blue stain)➡️This stain is for parenchymal cells, not for macrophages.
🔴Secondary hemochromatosis➡️the most common is frequent repated blood
transfusions.❗important❗.
🔴ry hyperparathyroidism leads to nephrocalcinosis ( metastatic calcification of renal tubules) Not Dystrophic . ❗MCQ❗
🔴❗Mcq❗ all of the following cause of Dystrophic Calcification except:Renal failure. ➡️هكي طريقة الدكتورة في الاسئلة
❗آخر محاضرة في cell injury❗:
Part1:
🔴Hemosiderin➡️Prussian blue iron stain:➡️the stain demonstrates the blue granules of hemosiderin in hepatocytes and Kupffer cells.❗important❗.
🔴Hemohidrosis does not involve tissue damage, unlike hematosis, which involves tissue damage.
🔴Hemochromatosis (H&E, Prussian blue stain)➡️This stain is for parenchymal cells, not for macrophages.
🔴Secondary hemochromatosis➡️the most common is frequent repated blood
transfusions.❗important❗.
🔴ry hyperparathyroidism leads to nephrocalcinosis ( metastatic calcification of renal tubules) Not Dystrophic . ❗MCQ❗
🔴❗Mcq❗ all of the following cause of Dystrophic Calcification except:Renal failure. ➡️هكي طريقة الدكتورة في الاسئلة
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Patho| باقي ملاحظات المحاضرة السابعة
❗آخر محاضرة في cell injury❗:
Part 2:
🔴Amyloid➡️diameter of 7-10 nm with electron microscopy.❗important❗.
🔴senile cardiac amyloidosis➡️ATTR transthyretin (un-mutated form) deposits in
Myocardium.❗McQ❗.
🔴Familial Amyloid Polyneuropathies is an autosomal dominant not recessive.❗Mcq❗.
🔴Familial Mediterranean Fever➡️Autosomal recessive disease➡️characterized by attacks of fever with inflammation of serosal surfaces (serositits).❗improtant❗.
🔴Old methods of demonstrating amyloid on gross specimen by using❗important❗:
1- Lugol’s iodine ➡️mahogany brown.
2- Diluted Sulfuric acid ➡️blue violet.
🔴Deposition of amyloid occurs in two patterns in spleen❗important❗:
1. Amyloid Deposits limited to the splenic follicles (white pulp), called Sago spleen.
2. Deposits in the walls of splenic sinuses in the red pulp), fusion of the amyloid deposits give rise to (Lardaceous spleen).
🔴Lardaceous spleen➡️It is named after lard (pig fat) because of its waxy, fatty-like appearance.
❗آخر محاضرة في cell injury❗:
Part 2:
🔴Amyloid➡️diameter of 7-10 nm with electron microscopy.❗important❗.
🔴senile cardiac amyloidosis➡️ATTR transthyretin (un-mutated form) deposits in
Myocardium.❗McQ❗.
🔴Familial Amyloid Polyneuropathies is an autosomal dominant not recessive.❗Mcq❗.
🔴Familial Mediterranean Fever➡️Autosomal recessive disease➡️characterized by attacks of fever with inflammation of serosal surfaces (serositits).❗improtant❗.
🔴Old methods of demonstrating amyloid on gross specimen by using❗important❗:
1- Lugol’s iodine ➡️mahogany brown.
2- Diluted Sulfuric acid ➡️blue violet.
🔴Deposition of amyloid occurs in two patterns in spleen❗important❗:
1. Amyloid Deposits limited to the splenic follicles (white pulp), called Sago spleen.
2. Deposits in the walls of splenic sinuses in the red pulp), fusion of the amyloid deposits give rise to (Lardaceous spleen).
🔴Lardaceous spleen➡️It is named after lard (pig fat) because of its waxy, fatty-like appearance.
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