🔬 Exciting News from Our Recent Paper! 🔬

📚 Title: In silico study of the impact of oxidation on pyruvate transmission across the hVDAC1 protein channel

Our recently published paper delves into the fascinating realm of cancer cell metabolism, focusing on the pivotal role of Voltage Dependent Anion Channels (VDACs), particularly VDAC1. Here's a snapshot of our findings:

🔍 Objective: Investigating the Effect of Low-Level VDAC1 Oxidation on Pyruvate Uptake

🧪 Methodology: Leveraging Molecular Dynamics (MD) Simulations

👉 Key Insights:
The overexpression of VDACs, especially VDAC1, in cancer cells compared to normal cells, has long been recognized. In our study, we honed in on the impact of a low level of VDAC1 oxidation, induced by Cold Atmospheric Plasma (CAP), on pyruvate (Pyr) uptake. Inhibiting Pyr uptake through VDAC1 emerges as a potential strategy to suppress cancer cell proliferation.

💡 Significant Findings:

Employed MD simulations to analyze hVDAC1 structure with modified cysteine and methionine residues.
Results indicated that the free energy barrier for Pyr translocation through the oxidized channel was significantly higher compared to the native channel.
Specifically, the barrier for Pyr translocation through the native channel was approximately 4.3 ± 0.7 kJ mol−1, while for the oxidized channel, it rose to 10.8 ± 1.8 kJ mol−1.
Higher barrier in the oxidized channel correlates with a decreased rate of Pyr permeation, suggesting a potential mechanism for inhibiting cancer cell proliferation.
🌐 Broader Implications:
Our findings unveil that low levels of CAP-induced oxidation reduce Pyr translocation, thereby curbing cancer cell proliferation. This suggests that subtle oxidative modifications may hold therapeutic potential in treating cancer cells by disrupting crucial metabolic pathways.

🚀 Future Directions:
Our research lays the groundwork for further exploration of CAP-induced oxidation as a targeted approach in cancer treatment. As we unravel the intricate connections between VDAC1, Pyr uptake, and cancer cell metabolism, we pave the way for innovative strategies in the fight against cancer.

🙌 Acknowledgments:
Kudos to our dedicated team for their commitment to advancing scientific knowledge and contributing to the ongoing discourse in cancer research. Together, we are shaping the future of cancer treatment!

#CancerResearch #ScienceBreakthrough #MolecularDynamics #ColdPlasma #InnovationInHealthcare #ResearchPublication

📸 Watch this video on Facebook
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VMD dasturini yuqori funksionalli yangi versiyasi chiqibdi (VIAMD):

Researchers uncover battery-like functions of mitochondria using super-resolution microscopes
https://phys.org/news/2023-11-uncover-battery-like-functions-mitochondria-super-resolution.html

Gemini is our natively multimodal AI model capable of reasoning across text, images, audio, video and code. This video highlights some of our favorite interactions with Gemini. Learn more and try the model: https://deepmind.google/gemini 0:00 Intro
0:19 Multimodal Dialogue
1:32 Multilinguality
2:04 Game Creation
2:31 Visual Puzzles
3:17 Making Connections
3:39 Image & Text Generation
4:06 Logic & Spatial Reasoning
4:55 Translating Visuals
5:27 Cultural Understanding

5 health experts, including Harvard professor Daniel Lieberman, share the exact ways exercise can lead to a healthier lifespan.

3D molekulyar vizualizatsiya - Suvning muzga aylanishi.

🌱✨ Exciting News in Agricultural Innovation! Our Latest Review Paper Unveils the Power of Non-Thermal Plasma in Seed Treatment! 🌾🔬

🌟 Key Findings:
Seed treatment with non-thermal plasma has shown remarkable effects on seeds through various applications such as direct plasma irradiation, plasma-activated water, plasma-activated Ringer’s lactate solution, and plasma-treated soil. Our review explores the diverse outcomes—both positive and negative—on seed germination and seedling growth.

💨 Pressure and Feed Gases Matter:
Discover how the impact of pressure and different feed gases influences the germination process and the growth of seedlings. Understanding these factors is crucial for optimizing plasma agriculture practices.

🔍 Focus on Reactive Species:
We delve into the types of reactive oxygen and nitrogen species (RONS) produced in both gas and liquid phases. The concentrations of these species play a pivotal role in determining germination percentage and seedling growth.

🌿 Key Takeaway:
Our research underscores that the success of plasma agriculture is intricately linked to seed morphology, the types and concentrations of reactive species, and specific plasma characteristics.

🚀 Join the Conversation:
We invite fellow researchers, agriculturists, and enthusiasts to dive into the future of sustainable and innovative farming practices. 🌍🌾

[UZ]📚 Navbatdagi kitob tavsiyasi 🌐✨
Jonah Bergerning "Yuqumlilik. Mahsulot va g‘oyalar qanday ommalashadi " asarini kashf eting! 🚀📖
Olim sifatida mahsulotlarni ommalashtirish san'ati haqida batafsil tushuncha beradigan kitobni o'qiganimdam mamnunman. Kitobda ko'pchilikni jalb qilish bo'yicha qimmatli tavsiyalar berilgan. Agar kelajakda mahsulot yaratsam, shubhasiz, ushbu kitobda bayon etilgan tamoyillarni qo'llayman.
Nima uchun ba'zi g'oyalar yong'in kabi tarqalib, boshqalari esa yonib ketayotganini hech o'ylab ko'rganmisiz? Yona Berger ushbu kitobda yuqumlilik asosini kash qilgan.
🧠 Sirlarni oching:
Nima uchun ba'zi narsalar virus kabi tarqalayotgani ortidagi psixologiyani o'rganing va g'oyalarni qaytarib bo'lmaydigan tarzda baham ko'radigan tamoyillar haqida tushunchaga ega bo'ling.
🌟 Asosiy tavsiyalar:
Siz sotuvchi, ijodkor yoki oddiygina ijtimoiy ta'sir dinamikasiga qiziqasizmi, o'z g'oyalaringizni qanday yuqumli qilish kerakligini bilib oling. Bergerning jozibali hikoyalari va tushunarli misollari murakkab holatlarni hamma uchun tushunarli qiladi.
👥 Fikrlab ko'ring:
Hayotingizda qanday g'oyalarni eng yuqumli deb hisoblaysiz? 🗣📚
🚀 Chuqur mulohaza qiling:
Fikringizni kuchaytiring va g'oyalarni nimaga jalb qilishini chuqurroq tushuning. Kitobni o'qing va yuyumlilik konseplarini atroflicha o'rganing.
[EN] 📚 The next book recommendation 🌐✨
Discover "Contagious: Why Things Catch On" by Jonah Berger! 🚀📖
As a scientist, I find great value in reading books that offer insights into the art of popularizing products. The book provides valuable recommendations on achieving widespread appeal. If I venture into product creation in the future, I will undoubtedly apply the principles outlined in this book.
Ever wondered why some ideas spread like wildfire while others fizzle out? Jonah Berger unravels the mysteries of contagious content in this captivating book.
🧠 Uncover the Secrets:
Explore the psychology behind why certain things go viral and gain insight into the principles that make ideas irresistibly shareable. From social currency to triggers and emotions, "Contagious" provides a fascinating journey into the science of popularity.
🌟 Key Takeaways:
Learn how to make your ideas more contagious, whether you're a marketer, creator, or simply curious about the dynamics of social influence. Berger's engaging storytelling and insightful examples make complex concepts accessible to everyone.
👥 Join the Conversation:
Share your thoughts! Have you read "Contagious," or is it on your reading list? What ideas do you find most contagious in your life? 🗣📚
🚀 Ignite Your Mind:
Empower your thinking and gain a deeper understanding of what makes ideas catch on. Grab your copy of "Contagious" and embark on a journey through the realms of influence and virality.

Ilmiy hazil 😂😂😂

Онлайн таълим учун фойдаланишингиз мумкин бўлган 5 та платформа рўйхати

1️⃣Media School Cabar.asia

2️⃣Coursera.org

3️⃣Khan Academy

4️⃣OpenLearn

5️⃣edX

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Is artificial intelligence capable of consciousness? We’ll hear from an expert who believes that AI is not as intelligent as we sometimes think, and as usual, we’ll be learning some new vocabulary as well. [BBC podcasts - 6 Minute English]

Dear colleagues,
Our GEC-IOPS (International Online Plasma Seminar) presentation is scheduled as follows
Date & Time: 21 Dec 2023 at 1:00 pm UTC
Title: Understanding non-equilibrium chemistry for carbon capture and utilization
Speaker: Hongtao Zhong
Stanford University

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Title: Estimating Electron-Molecule Ionization Cross Sections using Machine Learning
Speaker: Allison Harris
Illinois State University

​To join the seminar, please use the following link:

​https://us06web.zoom.us/j/86909230871?pwd=czNsUDVIL2FtWVRjWmpDYWRrUktYUT09​
Meeting ID: 869 0923 0871
Passcode: jC77pbWS