“上学的时候只知道mRNA，tRNA和rRNA，做了科研后才知道，原来还有MiRNA、SiRNA、LncRNA、PiwiRNA、CeRNA……”
太真实了（

https://zhuanlan.zhihu.com/p/270546478
这里面的视频好详细

我要学生物学自闭了
这都是些啥啊

"It is important for working biologists and for our patrons at the US National Institutes of Health and National Science Foundation and the equivalent bodies in other countries to realize that much of the tiny RNA revolution emerged from non-vertebrate genetic analysis—from plant biology, from worm genetics, from the fungi Neurospora crassa and Schizosaccharomyces pombe, from the protozoa Tetrahymena thermophila and from the trypanosomes. Much of this research was funded generously over the past decade or two, reflecting well on the wisdom of the administrators and peer review system, as well as on the governments who funded these programs. It is impossible to calculate the economic value of this tiny RNA revolution— it is explosive and thus not predictable. "
虽然说的好像没什么问题，可是真的很好笑

https://www.zhihu.com/question/427957844/answer/1556256991

说的真好 资瓷

“dsRNA can be conveniently introduced to the animals by microinjection, feeding or soaking”
草 可以喂RNA 太牛逼了！

两篇放我桌面好久了 没时间读的paper
要被我无情地从桌面移除了！
送给需要的人吧.jpg


https://www.nature.com/articles/s41594-020-0477-6?utm_source=nsmb_etoc&utm_medium=email&utm_campaign=toc_41594_27_10&utm_content=20201008&sap-outbound-id=0D1AF0EEBF55ACE132845522FCAD580196CCBB90

https://www.nature.com/articles/s41594-020-0475-8?utm_source=nsmb_etoc&utm_medium=email&utm_campaign=toc_41594_27_10&utm_content=20201008&sap-outbound-id=0D1AF0EEBF55ACE132845522FCAD580196CCBB90

“Because of their unusual appearance, which reminded us of a small squid, we named these mutants argonaute” Bohmert et al 1998

嗷 是乌贼娘基因！

我晕菜了
能不能不要这么绕TAT

miRNA好热哦

h3k9me3 组蛋白修饰