水水的摸鱼日常
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频道所有转发完全不代表本人观点

菜得一逼的鶸鸡生物搬砖狗的搬砖日常
博士四年级在读 quit倒计时ing
除了生物什么都做

做过Archaea,UAA,CRISPR-Cas,evolution,microbiome,barcode,RNA regulation,imaging,dev bio

Paper/Seminar Record: https://t.me/PaperReading
My daily crap: https://t.me/loveuchangeless
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prof: do you really want to know my strategy? i always go to bathroom since the study showed that releasing the body’s pressure can reduce the nervousness lol
Orthology may refer to: Orthology (biology) - Homologous sequences originate from the same ancestors (homolog e.g all globin protein), which are separated from each other after a speciation event, e.g. human beta and chimp beta globin.

paralogue (plural paralogues) (genetics) A pair of genes that derives from the same ancestral gene and now reside at different locations within the same genome.
In genetics, a selective sweep is the process through which a new beneficial mutation that increases its frequency and becomes fixed (i.e., reaches a frequency of 1) in the population leads to the reduction or elimination of genetic variation among nucleotide sequences that are near the mutation. In selective sweep, positive selection causes the new mutation to reach fixation so quickly that linked alleles can "hitchhike" and also become fixed.
synteny describes the physical co-localization of genetic loci on the same chromosome within an individual or species.
Link together a non-contiguous series of genomic sequences into a scaffold, consisting of sequences separated by gaps of known length. The sequences that are linked are typically contiguous sequences corresponding to read overlaps.
dN/dS is the ratio of the number of nonsynonymous substitutions per non-synonymous site (pN) to the number of synonymous substitutions per synonymous site (pS), which can be used as an indicator of selective pressure acting on a protein coding gene.
dN/dS measured across the whole protein sequence between two divergent species in theory tells you something about selection. If this ratio = 1, then the whole coding sequence evolves neutrally, when 0 < dN/dS < 1, it's under constraint, and when > 1 under positive selection.
Overdominance is a condition in genetics where the phenotype of the heterozygote lies outside the phenotypical range of both homozygous parents. Overdominance can also be described as heterozygote advantage, wherein heterozygous individuals have a higher fitness than homozygous individuals.

In genetics, underdominance (referred to in some texts as "negative overdominance") is the opposite of overdominance. It is the selection against the heterozygote, causing disruptive selection and divergent genotypes. Underdominance exists in situations where the heterozygotic genotype is inferior in fitness to either the dominant or recessive homozygotic genotype.
今天的实验有好结果!!!!!!!!!!!!
Kin selection is the evolutionary strategy that favours the reproductive success of an organism's relatives, even at a cost to the organism's own survival and reproduction. Kin altruism can look like altruistic behaviour whose evolution is driven by kin selection.
A structural gene is a gene that codes for any RNA or protein product other than a regulatory factor (i.e. regulatory protein).
Epistasis is a phenomenon in genetics in which the effect of a gene mutation is dependent on the presence or absence of mutations in one or more other genes, respectively termed modifier genes. In other words, the effect of the mutation is dependent on the genetic background in which it appears
Our additional finding that the elimination of sexual selection leads to the evolution of a substantially reduced rate of male courtship is also consistent with the hypothesis that mating displays can be sexually antagonistic.
The greater net reproductive rate of the monogamy populations shows that the cost of sexual selection exceeded its potential benefits and thereby maintained a measurable load on the promiscuous populations.
Intersex people are individuals born with any of several variations in sex characteristics including chromosomes, gonads, sex hormones or genitals that, according to the Office of the United Nations High Commissioner for Human Rights, "do not fit the typical definitions for male or female bodies".
Forwarded from 每个女孩都是最美的女孩 (百合子)
我做了一晚上的噩梦,梦到我连续两个考试得了全班最低分
结果早上起来就收到这个
我交了差不多1k字的proposal,结果你一个上午就把全班的final看完了?早知道这么水我昨天就随便写写了也不至于上周那么stressed TAT
Forwarded from 每个女孩都是最美的女孩 (百合子)
几个Postdoc去Yosemite叫上我一起
我:他们看我一个博一,会不会有点尴尬
师姐:不会的,你非常有Postdoc的气质,没事的时候都在聊科研