Actomyosin is inherently contractile, with the myosin motor protein able to pull on actin filaments. This property gives rise to contractile fibers that form the basis of skeletal muscle, and even in non-muscle cells, enable cell motility and force generation at the sub-cellular level.
Mechanotransduction (mechano + transduction) is any of various mechanisms by which cells convert mechanical stimulus into electrochemical activity.
Whether the mate sampling and choice performed by females in nature influences offspring performance is a controversial issue in theory and an open empirical question. Pronghorn (Antilocapra
americana) females engage in an obvious and energetically expensive mate sampling process to identify vigorous males. Although individual females sample independently, their choices converge on a small proportion of males that sire most young.
Offspring of attractive males were more likely to survive to weaning and to age classes as late as 5 years, resulting in a selection differential, calculated by expected differences in lifetime number of offspring weaned, of 0.32 against random mating.
Enhanced survival to weaning appeared to be accomplished by faster growth rates. Females compensated for matings with a less attractive mate by elevating rates of milk delivery to their young.
Because pronghorn males do not have costly ornaments, we conclude that female choice for good genes can exist in the absence of ornaments. Furthermore, female choice may be important and unrecognized as a force that can lower population genetic load
草 人类应该开放自由交配
不然我们的进化速度会被严重拖慢啊喂
americana) females engage in an obvious and energetically expensive mate sampling process to identify vigorous males. Although individual females sample independently, their choices converge on a small proportion of males that sire most young.
Offspring of attractive males were more likely to survive to weaning and to age classes as late as 5 years, resulting in a selection differential, calculated by expected differences in lifetime number of offspring weaned, of 0.32 against random mating.
Enhanced survival to weaning appeared to be accomplished by faster growth rates. Females compensated for matings with a less attractive mate by elevating rates of milk delivery to their young.
Because pronghorn males do not have costly ornaments, we conclude that female choice for good genes can exist in the absence of ornaments. Furthermore, female choice may be important and unrecognized as a force that can lower population genetic load
草 人类应该开放自由交配
不然我们的进化速度会被严重拖慢啊喂
Treadmilling is a phenomenon observed in many cellular cytoskeletal filaments, especially in actin filaments and microtubules. It occurs when one end of a filament grows in length while the other end shrinks resulting in a section of filament seemingly "moving" across a stratum or the cytosol.
https://mp.weixin.qq.com/s/B9mWXQrbwDYFltenG_9cbg
现有的RNA-seq技术存在两点不足之处：（1）由于传统建库过程中，RNA分子的捕捉等步骤具有序列偏好性，因此只能相对定量检测不同样品间相同RNA分子的变化倍数，而无法绝对定量分析同一样品中不同RNA分子；（2）RNA分子上的表观遗传修饰或复杂高级结构，可以阻断或影响逆转录反应，导致RNA-seq无法检测或定量分析含有修饰的RNA分子。
现有的RNA-seq技术存在两点不足之处：（1）由于传统建库过程中，RNA分子的捕捉等步骤具有序列偏好性，因此只能相对定量检测不同样品间相同RNA分子的变化倍数，而无法绝对定量分析同一样品中不同RNA分子；（2）RNA分子上的表观遗传修饰或复杂高级结构，可以阻断或影响逆转录反应，导致RNA-seq无法检测或定量分析含有修饰的RNA分子。
超声步骤为冰上3次 5秒的超声（50% 输出功率），控制超声探头位置，避免产生气泡。如没有超声仪，可用1mL注射器针头，冰上反复抽打裂解液5-10次，达到类似于超声的效果。
（草，这也太简陋[实用]了点
（草，这也太简陋[实用]了点
https://mp.weixin.qq.com/s/w1XZvIyiz8maQ6W1VSi5ew
注意，需使用实验级脱脂奶粉（Nonfat Dry Milk #9999）,食品级奶粉不可用于实验。（太草了
注意，需使用实验级脱脂奶粉（Nonfat Dry Milk #9999）,食品级奶粉不可用于实验。（太草了
Sexual antagonistic co-evolution is the relationship between males and females where sexual morphology changes over time to counteract the opposite's sex traits to achieve the maximum reproductive success