Dengue:-
• Caused by Dengue virus (Flavivirus); transmitted by Aedes aegypti mosquito (day-biter)
• Four serotypes: DENV-1, 2, 3, 4 —> infection by one ≠ immunity to others
• Antibody-Dependent Enhancement (ADE): prior infection can worsen severity on reinfection
• Severe dengue linked to immune overreaction + vascular leakage
• Urban disease: thrives in clean stagnant water, rapid urbanisation
• Climate change —> expands mosquito habitat (temperature + rainfall sensitive)

Newspaper takeaways:
• COMBAT project: Indo-EU initiative —> studies why dengue turns severe

• Uses AI + single-cell sequencing + biomarkers —> decode host response

• Organ-on-chip: lab simulation of human organs (no human testing)

• Qdenga (TAK-003): approved in India (18–60 yrs), ~84% efficacy, no pre-screening

• ICMR ‘DengiAll’: Phase-III, single-dose recombinant vaccine

• Key hurdle: ADE + 4 serotypes —> vaccine complexity

Link: https://t.me/bpscweb/43430

#CA2026

Uber cup 2026--> South Korea defeated China

Link: https://t.me/bpscweb/43478

#CA2026
#SPORTS
👇👇

Thomas Cup vs. Uber Cup

#SPORTS

The 2026 Davis Cup Final 8 will take place in Bologna, Italy from 24-29 November.

A total of 14 teams will compete in seven home-or-away ties, with the seven winners joining Italy in the Final 8.

Italy was crowned Davis Cup champion for the third consecutive year in 2025 after defeating Spain in the final.

#CA2025
#SPORTS
👇👇

Samarth Panchayat Portal

#CA2026
#PORTAL

Quila House also known as the Jalan Museum, Patna

#BIHARspecial

Ghatak UCAV = India’s indigenous stealth Unmanned Combat Aerial Vehicle (UCAV)

Developed by Defence Research and Development Organisation (DRDO)

Powered by indigenously developed turbofan engine (Kaveri derivative)

#CA2026
#DEFENCE

Trump launches ‘Project Freedom’ to open Strait of Hormuz

#CA2026

Natural Farming

#CA2026
#GS2mains

Hantavirus

#CA2026

Orbital AI Satellite =(Pathfinder)
• India’s 1st orbital data-centre satellite —> Pixxel + Sarvam AI partnership
• ~200 kg | Launch: 2026
• Carries data-centre grade GPUs —> AI training + inference in space
• Runs LLMs in orbit —> reduces dependence on ground cloud
• Concept: “compute in space where data is generated”—>(edge computing in space)

Orbital Data Centres — Core Idea
• Satellites acting as cloud/data centres in orbit
• Powered by continuous solar energy
• Enable real-time processing (edge computing in space)

Why Needed
• AI —> huge energy demand (data centres crisis)
• Space —> unlimited solar + natural cooling
• Reduces latency (no need to send data to Earth)
• Avoids land, water, regulation constraints

Link concept:- https://t.me/bpscweb/42070

TERAFAB Project:- https://t.me/bpscweb/42071

#CA2026
#SPACE

Satellite communication/Internet players in India

Link concept:-
https://t.me/bpscweb/37988
https://t.me/bpscweb/37358
https://t.me/bpscweb/34749

#CA2026