Blackboard Computing Adventures π‘
Away from considering the possibility of designing artificial ribosomes or synthetic natural ones, we shall also look at the possibility of extending this fundamentally crucial concept to that of printing ready-to-eat foods as well as non-natural living organismsβ¦
Guys, officially welcome to AUGUST
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Blackboard Computing Adventures π‘
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Among exciting new applications of TEA programming to GENETICS Research:
We see some neat way to transform a DNA sequence to its characteristic statistical summary (a modal sequence statistic)!
Who knows what's coming next...
State-of-the-Art DNA sequencing using TEA on the commandline? #phd #jwl #nuchweziresearch #genetics #transformatics work's still ongoing...
cat theta1_dna.txt | tttt -c "v:vSEQ|v:vANA:{}|u!:|v:vMS|l:lMS|y:vMS|d!:^.|v:vSY|y:vMS |d:^.|v:vMS|y:vSEQ|d*!:vSY|g:|v:|v!:|v:vSYN|g*:{}:vSY:vSYN|x*:vANA|v:vANA|y:vMS|f:^$:lFIN|j:lMS|l:lFIN|y:vANA" β β β C4G3T3A2We see some neat way to transform a DNA sequence to its characteristic statistical summary (a modal sequence statistic)!
Who knows what's coming next...
State-of-the-Art DNA sequencing using TEA on the commandline? #phd #jwl #nuchweziresearch #genetics #transformatics work's still ongoing...
Blackboard Computing Adventures π‘
Among exciting new applications of TEA programming to GENETICS Research: cat theta1_dna.txt | tttt -c "v:vSEQ|v:vANA:{}|u!:|v:vMS|l:lMS|y:vMS|d!:^.|v:vSY|y:vMS |d:^.|v:vMS|y:vSEQ|d*!:vSY|g:|v:|v!:|v:vSYN|g*:{}:vSY:vSYN|x*:vANA|v:vANA|y:vMS|f:^$:lFIN|j:lβ¦
Concerning DNA sequencing, we basically want to elegantly solve the following fundamental problem:
Given any two symbol sequences, S1 and S2, that potentially have overlaps (either common prefix or common suffix) or that have similar subsequences (potentially in the "inside" of either sequence, away from the edges) either once or more and of potentially varying lengths; problem 1: what is the longest common subsequence between S1 and S2? problem 2: how to correctly generate a single resultant/consensus sequence (S1β’S2) from both S1 and S2, that preserves their common subsequences and results in the most meaningful compromise subsequences on those regions where the two sequences are dissimilar?
Solving that Problem ππΌπ might totally leave all of GENETICS disrupted, but shall definitely result in solutions to problems in many other fields as well.
----[REFERENCE]:
Teresa Przytycka PhD, NCBI:
https://www.ncbi.xyz/CBBresearch/Przytycka/download/lectures/PCB_Lect10_Whole_Genome.pdf
#brainstorming #idea #problems #genomesequencing #postsanger #genetics #transformatics #sequenceanalysis #phd #jwl #fundamentals
Given any two symbol sequences, S1 and S2, that potentially have overlaps (either common prefix or common suffix) or that have similar subsequences (potentially in the "inside" of either sequence, away from the edges) either once or more and of potentially varying lengths; problem 1: what is the longest common subsequence between S1 and S2? problem 2: how to correctly generate a single resultant/consensus sequence (S1β’S2) from both S1 and S2, that preserves their common subsequences and results in the most meaningful compromise subsequences on those regions where the two sequences are dissimilar?
Solving that Problem ππΌπ might totally leave all of GENETICS disrupted, but shall definitely result in solutions to problems in many other fields as well.
----[REFERENCE]:
Teresa Przytycka PhD, NCBI:
https://www.ncbi.xyz/CBBresearch/Przytycka/download/lectures/PCB_Lect10_Whole_Genome.pdf
@misc{przytycka_wgs_lecture10,
author = {Teresa Przytycka},
title = {Lecture 10: Whole Genome Sequencing and Analysis},
year = {2025},
howpublished = {\url{https://www.ncbi.xyz/CBBresearch/Przytycka/download/lectures/PCB_Lect10_Whole_Genome.pdf}},
note = {Accessed August 2, 2025. Lecture slides from Introduction to Computational Biology.}
}#brainstorming #idea #problems #genomesequencing #postsanger #genetics #transformatics #sequenceanalysis #phd #jwl #fundamentals
Blackboard Computing Adventures π‘
Concerning DNA sequencing, we basically want to elegantly solve the following fundamental problem: Given any two symbol sequences, S1 and S2, that potentially have overlaps (either common prefix or common suffix) or that have similar subsequences (potentiallyβ¦
There's progress being made...
β We've defined and Mathematically formalized a Genome Sequencer, The Ribosome (Protein Generator), Gene Expression and more...
Keep waiting for the full research report...
Otherwise, we are rewriting the laws of #molecularbiology and especially #genetics from the ground up.. one step at a time... with clean and provable mathematics definitions, theorems and (yes!) laws!!!
Thanks #transformatics and the team at #nuchweziresearch, bringing modern sequencing theory to life.
Those dealing with animal and plant pathology, those designing machine learning and artificial intelligence using genetic algorithms, those exploring #bioautomata.. hahaha get excited! More details later. #jwl #phd the #foundations
β We've defined and Mathematically formalized a Genome Sequencer, The Ribosome (Protein Generator), Gene Expression and more...
Keep waiting for the full research report...
Otherwise, we are rewriting the laws of #molecularbiology and especially #genetics from the ground up.. one step at a time... with clean and provable mathematics definitions, theorems and (yes!) laws!!!
Thanks #transformatics and the team at #nuchweziresearch, bringing modern sequencing theory to life.
Those dealing with animal and plant pathology, those designing machine learning and artificial intelligence using genetic algorithms, those exploring #bioautomata.. hahaha get excited! More details later. #jwl #phd the #foundations
Blackboard Computing Adventures π‘
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Fut. Prof. JWL talks about his progress with developing TRANSFORMATICS as well as its applications to GENETICS.
Blackboard Computing Adventures π‘
Fut. Prof. JWL talks about his progress with developing TRANSFORMATICS as well as its applications to GENETICS.
And in exciting update!! Concerning our on-going [TRANSFORMATICS in] GENETICS Research...
Today, we started to understand how to express viruses in theory!
Today, we started to understand how to express viruses in theory!
Blackboard Computing Adventures π‘
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And today, we've considered the matter the optimal storage of DNA sequences, in databases especially, that also considers their optimal lookup mechanism.
#sequenceexpression #encodingformulae #godelnumbers #hashkeys #sequencecharacteristics #systems #theory
#sequenceexpression #encodingformulae #godelnumbers #hashkeys #sequencecharacteristics #systems #theory
Blackboard Computing Adventures π‘
And today, we've considered the matter the optimal storage of DNA sequences, in databases especially, that also considers their optimal lookup mechanism. #sequenceexpression #encodingformulae #godelnumbers #hashkeys #sequencecharacteristics #systems #theory
The theory for how to process hypothetical nucleic acid sequences, aka the Lu-Genome Expression System (LGES) has surely gotten it's legs today!! πππΌππππ Go see for yourself...
LINK: https://doi.org/10.6084/m9.figshare.29876024.v1
#genetics #genomeexpression #transformatics #phd #nuchweziresearch #profjwl
Lutalo, Joseph Willrich (2025). PLATONIC-EXA-landscape.pdf | A Basic Example of Full Genome Expression in the Lu-Genome Expression System. figshare. Dataset. https://doi.org/10.6084/m9.figshare.29876024.v1
LINK: https://doi.org/10.6084/m9.figshare.29876024.v1
#genetics #genomeexpression #transformatics #phd #nuchweziresearch #profjwl
Blackboard Computing Adventures π‘
The theory for how to process hypothetical nucleic acid sequences, aka the Lu-Genome Expression System (LGES) has surely gotten it's legs today!! πππΌππππ Go see for yourself... Lutalo, Joseph Willrich (2025). PLATONIC-EXA-landscape.pdf | A Basic Example ofβ¦
MENSA at work... #phd #dreams... somebody... I mean, #universityofoxford pls!! SOS!
ππππ #rngs meets #genetics and all chaos broke loose!!! #jwl @bclectures
ππππ #rngs meets #genetics and all chaos broke loose!!! #jwl @bclectures
Blackboard Computing Adventures π‘
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A book on some pretty advanced but fundamentally relevant Mathematics that I have distilled and developed for the field of *GENETICS*
Some sneak previews here for you. My first monograph on the especially molecular biology and bioinformatics aspects of Genetics and Genetic Engineering, as approached from especially a *mathematical point of view, especially using a new theory of statistical mathematics and sequence analysis* known as TRANSFORMATICS.
Cheers one again.
ββ J. Willrich Lutalo, *PhD student, Oxford, Nuchwezi Research*
#correspondences #professors #bioinformatics #molecularbiology #theoreticalbiology #puremathematics #transformatics
Some sneak previews here for you. My first monograph on the especially molecular biology and bioinformatics aspects of Genetics and Genetic Engineering, as approached from especially a *mathematical point of view, especially using a new theory of statistical mathematics and sequence analysis* known as TRANSFORMATICS.
Cheers one again.
ββ J. Willrich Lutalo, *PhD student, Oxford, Nuchwezi Research*
#correspondences #professors #bioinformatics #molecularbiology #theoreticalbiology #puremathematics #transformatics
Blackboard Computing Adventures π‘
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Let's see... What's really going on??
Different people would look at it differently, but overall, some few words can help paint the best picture.. a new field by #ugandan #mathematician and #researcher called #transformatics and lots of quirky gems for those into #genetics and... #sequences at all levels! #staytuned!
O! And yes, use a #tagcloud world clout? WordCloud? #wordcloud like this β
Different people would look at it differently, but overall, some few words can help paint the best picture.. a new field by #ugandan #mathematician and #researcher called #transformatics and lots of quirky gems for those into #genetics and... #sequences at all levels! #staytuned!
O! And yes, use a #tagcloud world clout? WordCloud? #wordcloud like this β