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Clinical features of viral infection

🧨 HHV1........ oral ulceration

🧨 HHV2........Genital ulceration

🧨 HHV3........ Rash

🧨 HHV4 and HHV5
infectious mononucleosis
🧨 Mumbs ........parotid swelling

🧨 Measle........ koplic spot

🧨 PIV........ Croup

🧨 Yersinia pestis........ plaque

🧨 Corynobacterium diphterea........ Diphtheria
🧨 Mycobacterium T.B........ tuberculosis

Commonest cause

🧨 Pneumonia between 5 - 35 years?
Mycoplasma pneumoniae

🧨 Pneumonia in pt with HIV?
Pneumcystis jirovecii

🧨 Pneumonia in alcoholics?
Klebsela

🧨 Post influenza pneumonia?
S ausrus

🧨 Croup?
Parainfluenza virus

🧨 Acute bronchiolitis
RSV

🧨 Common cold?
Rhinovirus

🧨 Sinusitis?
S pnemonia

🧨 Pneumonia?
S.peumonia

🧨 Parapneumonic effusion?
S.pneumoniae

🧨 Empyema?
S.pneumoniae

❄️Features of some organisms

🧨 Streptococcus pneumonia
Gram+ve cocci

🧨 Mycoplasma pneumoniae
Gram- ve bacilli

🧨 Legoinella
Gram -ve bacilli

🧨 Pneumcystis jirovecii
Fungus

🧨 Mycbacterium TB
Acid fast bacilii

🧨 Paramyxoviridea ( Parainfluenza virus.. Measles.. Mumbs... RSV...)
Single stranded - sense RNA virus

🧨 Herbs viruses
HHV1...HHV2...HHV3(Varicella zoster) HHV4 ( Epstian Bar Virus) HHV5 cytomegalovirus
Double stranded DNA Enveloped virus

the organism with the following feature
🧨 Murcary droplet in culture
Brodetella
🧨 Dark pigmented culture
Yersinia
🧨 Transmitted by flea bite
Yersinia
🧨 Need both factor X&V
H.influnzea
🧨 Produce lipotechoic acid
S. Pneumoniae
🧨 Produce toxin damage cilliated epithelium In lungs
Brodetella
🧨 Gram _ a Hemolytic
S. Pneumoniae

🧨 Herps viruses🧨

🧨 Structure.:-
💙Icosahedra symmetry.
💙Enveloped.
💙Contain tegument, B protein and G protein.

🧨 Assembly of these virus take place in nucleus
Envelopment take place in the inner nuclear membrane

🧨HHV1 and HHV2 infect epithelium
Latency in neuron

🧨Varicella zoster🧨

🩸Varicella
🦋Mild in chideren
🦋Severe in adult
🦋All of the cases are clinical

🩸Herps zoster
🦋Reactivation of the virus
🦋Associated with low immunity

❤️Previous antibody formation is confer live long immunity for vareclla not zoster

🩸Cytomegalo virus🩸
🦋 Produce cytopathic effects
🦋Can be transmitted vertically
🦋Manifest as infectious mononucleosis

🩸EBV🩸
🧨 Cause acute infectious mononucleosis

🧨Associated with :
❤️ Nasopharngeal carcinoma
❤️Hodgkins lymphoma
❤️Gastric carcinoma

🏴‍☠Target of the virus B Cell
🏴‍☠Subclinical in children
🏴‍☠Mode of transmission
(Respiratory droplet 💧SALIVA)

🧨Features of infectious mononucleosis are :-
💙Fever.
💙Lymphadenopathy
💙Sore throat
💙Atypical lymphcytosis

🧨 Test........ monospot test

❤️❤️Paramyxoviridea❤️❤️

🩸Paramyxovirus
Parainfluenza virus
Mumbs virus
🩸Morbili virus
Measels
🩸Pneumovirus
RSV

🧨They have helical symmetry
🧨All of them cause viremia except (RSV_PIV)
🧨 Some of them prevented by vaccine called MMR
(Mumbs Measle Rubella)

🧨This family differ from orthomyxovirdea in that
💙orthomyxovirdea
Replicte on nucleus
Segmented genom
💙Paramyxoviridea
Replicate in cytoplasm
Non segmented

🩸Parainfluenza viruses🩸
🦋4 serotybe
🦋Have short live immunity
🦋Contain hemaglutini neuramindase

🧨 HPIV1 HPIV3 cause pneumonia
🧨 HPIV1 HPIV2 HPIV3 cause Croup

What is Croup
Infection of larynx, trachea bronchi

🧨 What is the clinical presentation of Croup :-
🦋barking couph
🦋Inspiratory straidor

💙💙❤️مساكات Respiratory💙💙❤️

🧨 Patient with a hoarse Barking couph + inspiratory stridor
Croup
🧨 Drooling +Dysphagia +muffled voice + inspiratory stridor
Acuts epiglottitis

🧨 Consolidation of entire lobe of the lung on chest x ray
Lobar pneumonia

🧨 Weight loss + night sweating + couph with hemoptysis + prolonged fever
T.B

🧨 Dyspnea + non productive couph + wight loss + fever + polyarthlagia and come from afrocarrbian
Sarcoidosis

🧨 Productive couph lasting af least 3 month over 2 years + thick mucous in bronchial wall

Chronic bronchitis

🧨 Smoker dyspnea and couph prolonged expiration with pursed lips +barrel shape chest on x ray
Emphysema

🧨 Episodic attack of dysnpea and wheezing after exposure to allergic stimuli and family history of similar condition
Asthma

🧨 Couph and dyspnea and foul smelling breath
Bronchiectisis

🧨 Preterm baby + has increasing Respiratory effort after birth tachypanea use of accessory inspiratory muscle + cyanosis
Respiratory distress syndrome

🧨 Smoker + weight loss + central mass on chest x ray + high serum calcium or high serum PTHrP
Squamous cell carcinoma

🧨 Nonsmoker or female + peripheral lung tumor adenocarcinoma

🧨 Male smoker + central mass in the lung + paraneoplastic syndrome or high ADH, ACTH
Squamous cell carcinoma

🧨 Hyperresonant chest percussion +rib fraction + collapse of a portion of the lung
Tension pneumothorax

🧨shipyard worker + interstitial fibrosis of lung with golden brown fiber.. Plural effusion + chest pain
Mesothelioma

Stony dullness to percussion + dyspnea
Pleural effusion

🧨 triad of situs inversus, pansinusitis, and bronchiectasis
Kartagener syndrome

Most common cause of :

🧨Rhinitis
Rhino virus

🧨 Acute epiglottitis
H. influenzae type b

🧨 laryngotracheobronnchitis croup
Parainfluenza virus

🧨 Lobar pneumonia
Streptococcus pneumoniae

🧨 Emphysema
Smoking

🧨Bronchiolitis
RSV

🧨 Common cause of lung cancer overall
Metastasis from another organ

🧨Common cause of primary lung cancer
Small cell carcinoma

🧨 Lung cancer in female or non smoker
Adenocarcinoma


🧨 Pneumonia in alcoholics?
Klepseilla

🧨 Post influenza pneumonia?
S auerus

🧨 Pneumonia in pt with HIV?
S. Pneumoniae

🧨 Pneumonia between 5 - 35 years?
Mycoplasma pneumoniae

🧨 Plural effusion
Bacterial pneumonia

🧨 Pneumonia in older patients with cystic fibrosis
Pseudomonas aeruginosa

🧨childhood cause of nasal polyposis is
Cystic fibrosis


🧨 congenital laryngeal anomaly that produces stridor is
Larngomalacia



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امتحان 30 كارديو 👇

1.D
2.A
3.B
4.D
5.C
6.B

7.C
8.A
9.D
10.B
11.A
12.C
13.A

18 C
19 B
20 B

23. C
24. B
25. D
26. D
27. A
28. A

29. B
30. B
31. C
32. C
33. C
34. A
35. A

36. B
37. C
38. C
39. A
40. A
41. A

42. C
43. B
44. A
45. D
46. D

47. C
48. D
49. B
50. C
51. B
52. B

53. A
54. A
55. D
56 D
57 B
58. D
59. D

60. A
61. A
62. A
63. B
64. D
65. A
66. C
67. D