Aspiring Physicians 57🥼⚡️ pinned «Six amino acids form pyrovate: 🔴 Alanine 🟢 glycine 🟤 Serine 🟣 Cystine 🟡 Hydroxyproline 🔷 Therioene 🔶 Cystonsis: storage disease rare lysosomal 🔺 Cystinura: disorder characterized by elevated of urinary Excertion defect of four amino acid which is…»
All of the following inhibit alpha ketoglutrate except
Anonymous Quiz
8%
ATP
0%
NADH
22%
Succincyl COA
12%
GTP
57%
Ca
Which of the following amino acid form propinoyl COA
Anonymous Quiz
10%
Tyrosine
8%
Alanine
16%
Glycine
33%
Methionine
33%
All of the above
🤓2
VLDL is primarily responsible for transport of
Anonymous Quiz
17%
Dietary triglycerides
62%
Endogenous triglycerides
14%
Cholesterol from tissues
2%
Phospholipids only
5%
Bile salts
❤2
Type III hyperlipoproteinemia is associated with mutation in
Anonymous Quiz
15%
LDL receptor
38%
ApoE
0%
ApoB48
4%
ApoC. II
19%
A and B
23%
B and D
❤2
Select the one false statement about lipoprotein lipase
Anonymous Quiz
0%
found bound to the surface of the capillary endothelium by heparin sulfate proteoglycans
6%
hydrolyses the triglyceride in chylomicrons and VLDL.
31%
its deficiency is inherited in an autosomal recessive pattern
56%
colipase, inhibits the catalytic activity of lipoprotein lipase
6%
apoC-II binds to and activates LPL
Pancreatic lipase breaks triglycerides down into which two digestive products?
Anonymous Quiz
0%
Free fatty acids and monosaccharides
0%
Monosaccharides and monoglycerides
62%
Free fatty acids and monoglycerides
14%
Free fatty acids and triglycerides
24%
Free fatty acids and diglycerides
Which of the following is not needed for the synthesis of fatty acids:
Anonymous Quiz
7%
NADPH
10%
Acetyl CoA
10%
ATP
62%
ADP
10%
Fatty acid synthase complex
_______________ is a rare, autosomal recessive disorder caused by a deficiency of peroxisomal PhyH results in the accumulation of phytanic acid in the plasma and tissues:
Anonymous Quiz
7%
Jamaican vomiting sickness
85%
Refsum disease
4%
Sjögren-Larsson syndrome
0%
Crohn disease
4%
Reye syndrome
The rate-limiting step in the synthesis of ketone bodies is:
Anonymous Quiz
50%
The HMG CoA synthase
14%
The HMG CoA lyase
18%
The HMG CoA hydroxylase
18%
The HMG CoA synthetase
Which of the following lipoprotein contains the highest protein content among all the lipoproteins:
Anonymous Quiz
7%
VLDL
3%
LDL
10%
Chylomicrons
79%
HDL
0%
IDL
Which of the following is statement is not correct about faty acid oxidation:
Anonymous Quiz
4%
a.Increased fatty acids oxidation is a characteristic of starvation and of diabetes mellitus
0%
b.Impairment in FAs oxidation leads to hypoglycemia
17%
c.Final cleavage product of odd chain oxidation is propionyl - CoA
52%
d.The methyl group on the carbon number 2 of phytanic acid blocks B-oxidation
26%
e.w-Oxidation involves a monooxygenase enzyme that requires O2 and Cyt. Paso
❤2
The symptoms that characterized the absence of peroxisomes in all tissues, and by accumulation of C26-C38polyenoicFAs in brain tissue
Anonymous Quiz
5%
a.Carnitine Palmitoy|transferase I
10%
b.Dicarboxylic Aciduria
81%
c. Zellweger's Syndrome
0%
d.Jamaican Vomiting Sickness
5%
e.Ketosis
Regarding lipoproteins, select the one false statement:
Anonymous Quiz
6%
a.Lipoprotein(a) is a low-density lipoprotein variant known as a risk factor for atherosclerosis
6%
b.Apo C Il known as lipoprotein lipase activator
63%
c.HDL synthesized only by the liver
6%
d.Lipoprotein Lipase is located at on the walls of blood capillaries
19%
e.Each LDL particle is derived from a single VLDL particle
Select the one false statement about the carnitine shuttle:
Anonymous Quiz
10%
a. Long-chain acyl-CoA (or FFA) cannot penetrate the inner membrane of mitochondria
15%
b.Carnitine palmitoyltransferase-I converts long-chain acyl-CoA to acylcarnitine
40%
c.Carnitine-acylcarnitine translocase acts is the most important enzyme of fatty acids oxidation
20%
d.Acylcarnitineis transported in, coupled with the transport out of one molecule of carnitine
15%
e.Acylcarnitinethen reacts with CoA, catalyzed by carnitine palmitoy|transferase-ll
Regarding B- oxidation select the incorrect statement
Anonymous Quiz
4%
a.Occurs in matrix of mitochondria
13%
b.In B-oxidation two-carbon fragments are successively removed in the form of acetyl-CoA
35%
c.The carbon 2 of a fatty acid is oxidized
13%
d. Fatty Acid Activation by esterification with CoASH
35%
e. Acyl-CoA synthetase catalysis the only step that requires energy in B oxidation
Select the one correct answer regarding the extra enzymes involved in oxidation of unsaturated fatty acids
Anonymous Quiz
5%
a.Delta 3 enoylCoA isomerase
0%
b.Delta 2 enoylCoA isomerase
14%
c.Delta 2 enoylCoA hydratase
18%
d.& 2,4 dienoyl-CoA reductase
64%
e.Both a & d
Refsum's disease is due to deficiency of which of the followings?
Anonymous Quiz
54%
a.a-Hydroxylase
0%
b.a- Reductase
13%
c.B-Hydroxylase
13%
d.B- Carboxylase
21%
e.None of the above