Misinterpretation of chimeric virus study at Boston University
https://www.biorxiv.org/content/10.1101/2022.10.13.512134v1.full
Purpose: To determine the contribution of Spike to pathogenicity of SARS-CoV-2
Approach: "We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 and compared this virus with the naturally circulating Omicron variant."
Details: In hACE2 mice, Wuhan (WT) is 100% lethal and Omicron is nonlethal. When Omicron Spike replaces Wuhan Spike, pathogenicity decreases from 100% to 80%, thus an attenuated strain of Wuhan was generated. This is not a gain of function but rather a LOSS of function.
Conclusion: "Major determinants of viral pathogenicity reside outside of S"
What is the necessity of chimeric virus research and the unethical approach to creating new recombinant viruses with unknown pathogenicity and outbreak potential? Should the U.S. have lifted the ban on Gain of Function research in 2017?
@takescienceback
https://www.biorxiv.org/content/10.1101/2022.10.13.512134v1.full
Purpose: To determine the contribution of Spike to pathogenicity of SARS-CoV-2
Approach: "We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 and compared this virus with the naturally circulating Omicron variant."
Details: In hACE2 mice, Wuhan (WT) is 100% lethal and Omicron is nonlethal. When Omicron Spike replaces Wuhan Spike, pathogenicity decreases from 100% to 80%, thus an attenuated strain of Wuhan was generated. This is not a gain of function but rather a LOSS of function.
Conclusion: "Major determinants of viral pathogenicity reside outside of S"
What is the necessity of chimeric virus research and the unethical approach to creating new recombinant viruses with unknown pathogenicity and outbreak potential? Should the U.S. have lifted the ban on Gain of Function research in 2017?
@takescienceback
The Supreme Court of New York finds vaccination mandates unconstitutional declaring them arbitrary and capricious.
https://iapps.courts.state.ny.us/fbem/DocumentDisplayServlet?documentId=JK5E3gx5XV1/ku37jnWR_PLUS_w==&system=prod
@takescienceback
https://iapps.courts.state.ny.us/fbem/DocumentDisplayServlet?documentId=JK5E3gx5XV1/ku37jnWR_PLUS_w==&system=prod
@takescienceback
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In July 2021 the US FDA quietly disclosed findings of a potential increase in four types of serious adverse events in elderly people who had had Pfizer’s covid-19 vaccine: acute myocardial infarction, disseminated intravascular coagulation, immune thrombocytopenia, and pulmonary embolism.
The unadjusted relative risk ratio estimates originally found for the four serious adverse events ranged from 42% to 91% increased risk. More than a year later, however, the status and results of the follow-up study are unknown.
"To keep this information from the scientific community and prevent us from analysing it ourselves, is irresponsible. It presumes that these organisations are perfect and cannot benefit from independent scrutiny,” says Joseph Fraiman, an emergency medicine physician in New Orleans.
https://www.bmj.com/content/379/bmj.o2527
@takescienceback
The unadjusted relative risk ratio estimates originally found for the four serious adverse events ranged from 42% to 91% increased risk. More than a year later, however, the status and results of the follow-up study are unknown.
"To keep this information from the scientific community and prevent us from analysing it ourselves, is irresponsible. It presumes that these organisations are perfect and cannot benefit from independent scrutiny,” says Joseph Fraiman, an emergency medicine physician in New Orleans.
https://www.bmj.com/content/379/bmj.o2527
@takescienceback
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Heavy menstrual bleeding added as a side effect to genetic Covid vaccines by the European Medicines Agency.
"After reviewing the data, the Committee concluded that there is at least a reasonable possibility that the occurrence of heavy menstrual bleeding is causally associated with these vaccines and therefore recommended the update of the product information."
https://www.ema.europa.eu/en/news/meeting-highlights-pharmacovigilance-risk-assessment-committee-prac-24-27-october-2022
"After reviewing the data, the Committee concluded that there is at least a reasonable possibility that the occurrence of heavy menstrual bleeding is causally associated with these vaccines and therefore recommended the update of the product information."
https://www.ema.europa.eu/en/news/meeting-highlights-pharmacovigilance-risk-assessment-committee-prac-24-27-october-2022
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Following addition of genetic Covid vaccinations to the US childhood immunization schedule, parents must take action themselves to safeguard future generations.
Find more information about exemptions & homeschooling at the links below.
https://vaccines.procon.org/state-vaccination-exemptions-for-children-entering-public-schools/
https://www.homeschool.com/articles/questions-about-homeschooling/
@takescienceback
Find more information about exemptions & homeschooling at the links below.
https://vaccines.procon.org/state-vaccination-exemptions-for-children-entering-public-schools/
https://www.homeschool.com/articles/questions-about-homeschooling/
@takescienceback
Encyclopedia Britannica
School Vaccine Mandates
Should states be allowed to mandate vaccines for school attendance? Learn the pros and cons of the debate.
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Seres Therapeutics’ SER-109 may become first FDA-approved oral microbiome therapeutic.
The drug's efficacy highlights the benefit of maintaining a healthy gut microbiome.
A healthy gut does not require drug intervention to have a balanced microbiome, most of the time.
Restoring gut health can be easily achieved by dietary changes. This will provide illness symptom reduction and proper immune function.
https://www.mdpi.com/2079-6382/11/9/1234
https://www.fiercebiotech.com/biotech/seres-step-closer-bringing-first-microbiome-therapy-market-fda-mulls-approval
@takescienceback
The drug's efficacy highlights the benefit of maintaining a healthy gut microbiome.
A healthy gut does not require drug intervention to have a balanced microbiome, most of the time.
Restoring gut health can be easily achieved by dietary changes. This will provide illness symptom reduction and proper immune function.
https://www.mdpi.com/2079-6382/11/9/1234
https://www.fiercebiotech.com/biotech/seres-step-closer-bringing-first-microbiome-therapy-market-fda-mulls-approval
@takescienceback
MDPI
SER-109: An Oral Investigational Microbiome Therapeutic for Patients with Recurrent Clostridioides difficile Infection (rCDI)
Clostridioides difficile infection (CDI) is classified as an urgent health threat by the Centers for Disease Control and Prevention (CDC), and affects nearly 500,000 Americans annually. Approximately 20–25% of patients with a primary infection experience…
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🔥 New preprint study from Ioannidis group
Across 31 systematically identified national seroprevalence studies in the pre-vaccination era, the median infection fatality rate of COVID-19 was estimated to be 0.035% for people aged 0-59 years people and 0.095% for those aged 0-69 years.
*The median #IFR was
0.0003% at 0-19 years,
0.003% at 20-29 years,
0.011% at 30-39 years,
0.035% at 40-49 years,
0.129% at 50-59 years, and
0.501% at 60-69 years.
*At a global level, pre-vaccination IFR may have been as low as 0.03% and 0.07% for 0-59 and 0-69 year old people, respectively.
*These IFR estimates in non-elderly populations are lower than previous calculations had suggested.
@takescienceback
https://www.medrxiv.org/content/10.1101/2022.10.11.22280963v1
Across 31 systematically identified national seroprevalence studies in the pre-vaccination era, the median infection fatality rate of COVID-19 was estimated to be 0.035% for people aged 0-59 years people and 0.095% for those aged 0-69 years.
*The median #IFR was
0.0003% at 0-19 years,
0.003% at 20-29 years,
0.011% at 30-39 years,
0.035% at 40-49 years,
0.129% at 50-59 years, and
0.501% at 60-69 years.
*At a global level, pre-vaccination IFR may have been as low as 0.03% and 0.07% for 0-59 and 0-69 year old people, respectively.
*These IFR estimates in non-elderly populations are lower than previous calculations had suggested.
@takescienceback
https://www.medrxiv.org/content/10.1101/2022.10.11.22280963v1
medRxiv
Age-stratified infection fatality rate of COVID-19 in the non-elderly informed from pre-vaccination national seroprevalence studies
The infection fatality rate (IFR) of COVID-19 among non-elderly people in the absence of vaccination or prior infection is important to estimate accurately, since 94% of the global population is younger than 70 years and 86% is younger than 60 years. In systematic…
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In the third quarter, Comirnaty accounted for $4.4 billion in sales, including $2.9 billion in the U.S. With the result, Pfizer bumped up its projection for COVID vaccine sales for the year by $2 billion to a total of $34 billion. It also adjusted its annual revenue projection for the company overall to a range of between $99.5 and $102 billion.
https://www.fiercepharma.com/pharma/pfizers-comirnaty-rakes-44b-third-quarter-company-adjusts-annual-projection-34b
@takescienceback
https://www.fiercepharma.com/pharma/pfizers-comirnaty-rakes-44b-third-quarter-company-adjusts-annual-projection-34b
@takescienceback
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🎙 Excellent interview with Dr. Amerling!
“The current system is so corrupt at this point that it is impossible to fix, in my view. We have to start from scratch and build something alongside as an alternative,” he said.
“Let’s just build our own system that will be free from industry influence. We’re not going to have pharma telling us what drugs to give and when. We’re not going to have guidelines committees to tell doctors how to practice.”
https://www.theepochtimes.com/many-common-diseases-are-reversible-with-diet-but-medical-industry-favors-drugs-doctor_4835451.html
@takescienceback
“The current system is so corrupt at this point that it is impossible to fix, in my view. We have to start from scratch and build something alongside as an alternative,” he said.
“Let’s just build our own system that will be free from industry influence. We’re not going to have pharma telling us what drugs to give and when. We’re not going to have guidelines committees to tell doctors how to practice.”
https://www.theepochtimes.com/many-common-diseases-are-reversible-with-diet-but-medical-industry-favors-drugs-doctor_4835451.html
@takescienceback
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📖 Harvard Mandates New COVID-19 Booster, Threatens Holds on Enrollment if Students Don’t Comply
"Students must be compliant with all vaccine requirements in order to register for the spring term. This includes the annual flu shot as well as the bivalent Omicron-specific COVID-19 booster."
https://huhs.harvard.edu/news/fall-2022-immunization-requirement-alert#gsc.tab=0
New datasets show Bivalent Covid genetic vaccines updated with Omicron sequences are even less effective than the original vaccine (see Table S12 in publication below).
Covid genetic vaccination has an unfavorable risk-benefit scenario. There is a negligible risk of disease from SARS-CoV-2 in healthy, young adults but demonstrated risk of myocarditis (and other side effects) from vaccination.
https://www.nejm.org/doi/full/10.1056/NEJMoa2208343
@takescienceback
"Students must be compliant with all vaccine requirements in order to register for the spring term. This includes the annual flu shot as well as the bivalent Omicron-specific COVID-19 booster."
https://huhs.harvard.edu/news/fall-2022-immunization-requirement-alert#gsc.tab=0
New datasets show Bivalent Covid genetic vaccines updated with Omicron sequences are even less effective than the original vaccine (see Table S12 in publication below).
Covid genetic vaccination has an unfavorable risk-benefit scenario. There is a negligible risk of disease from SARS-CoV-2 in healthy, young adults but demonstrated risk of myocarditis (and other side effects) from vaccination.
https://www.nejm.org/doi/full/10.1056/NEJMoa2208343
@takescienceback
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CANCER CAUSING AGENTS IN MASKS
"In 2017, the Risk Assessment Committee (RAC) of the European Chemical Agency (ECHA) reviewed the carcinogenic potential of TiO2 and proposed to classify Titanium dioxide as Carc. 2, H351, a suspected human carcinogen by inhalation.
For all examined face masks, the amount of TiO2 particles at the surface of the textile fibers notably exceeds the acceptable exposure level.
A health risk cannot be ruled out when face masks containing polyester, polyamide, thermobonded non-woven and bi-component fibers, are used intensively."
https://www.nature.com/articles/s41598-022-06605-w
@takescienceback
"In 2017, the Risk Assessment Committee (RAC) of the European Chemical Agency (ECHA) reviewed the carcinogenic potential of TiO2 and proposed to classify Titanium dioxide as Carc. 2, H351, a suspected human carcinogen by inhalation.
For all examined face masks, the amount of TiO2 particles at the surface of the textile fibers notably exceeds the acceptable exposure level.
A health risk cannot be ruled out when face masks containing polyester, polyamide, thermobonded non-woven and bi-component fibers, are used intensively."
https://www.nature.com/articles/s41598-022-06605-w
@takescienceback
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"Deafening Silencing is a series documenting the widespread and indiscreet use of direct censorship, de-platforming, smearing, coercing and other attempts to silence individuals questioning the official narrative on the Covid-19 event and the associated vaccines. The crude censorship methods employed by the mainstream press and large tech corporations enable and support the equally crude propaganda our societies are flooded with."
https://www.pandata.org/deafening-silencing/
@takescienceback
https://www.pandata.org/deafening-silencing/
@takescienceback
PANDA
Deafening Silencing - PANDA
Discover how the propaganda war was waged using censorship, smearing, and coercion in our articles by PANDA. Click to read.
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Yet another study highlights that the risk-benefit scenario does NOT favor vaccination for Covid-19, particularly in young, healthy age groups.
Furthermore, a higher incidence of heart inflammation directly correlates with an increased dose of Spike mRNA used for the moderna vaccine. Spike is toxic to heart muscle and also causes formation of amyloid fibrils that likely play a role in microclotting.
"..we observed a 2- to 3-fold higher odds [of myocarditis/pericarditis] among individuals who received mRNA-1273 vs BNT162b2. The rate of myocarditis following mRNA-1273 receipt is highest among younger men (age 18-39 years)."
https://www.jacc.org/doi/abs/10.1016/j.jacc.2022.08.799
@takescienceback
Furthermore, a higher incidence of heart inflammation directly correlates with an increased dose of Spike mRNA used for the moderna vaccine. Spike is toxic to heart muscle and also causes formation of amyloid fibrils that likely play a role in microclotting.
"..we observed a 2- to 3-fold higher odds [of myocarditis/pericarditis] among individuals who received mRNA-1273 vs BNT162b2. The rate of myocarditis following mRNA-1273 receipt is highest among younger men (age 18-39 years)."
https://www.jacc.org/doi/abs/10.1016/j.jacc.2022.08.799
@takescienceback
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Spike protein heart damage is revealed in research funded by the British Heart Foundation.
The cellular mechanism published below is the likely cause of myocarditis/pericarditis following genetic Covid vaccination. It is still unclear why this occurs most frequently in healthy, young males.
"Importantly, we show that a recombinant S protein alone elicits cellular signalling through the CD147 receptor in cardiac pericytes, thereby inducing cell dysfunction and microvascular disruption ... (and) production of pro-apoptotic factors causing endothelial cell death."
https://portlandpress.com/clinsci/article/135/24/2667/230273/The-SARS-CoV-2-Spike-protein-disrupts-human
@takescienceback
The cellular mechanism published below is the likely cause of myocarditis/pericarditis following genetic Covid vaccination. It is still unclear why this occurs most frequently in healthy, young males.
"Importantly, we show that a recombinant S protein alone elicits cellular signalling through the CD147 receptor in cardiac pericytes, thereby inducing cell dysfunction and microvascular disruption ... (and) production of pro-apoptotic factors causing endothelial cell death."
https://portlandpress.com/clinsci/article/135/24/2667/230273/The-SARS-CoV-2-Spike-protein-disrupts-human
@takescienceback
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ICAN has directed its legal team to challenge every single state that mandates its students to receive a COVID-19 vaccine and will continue to be on the frontlines defending you!
"While most post-March 2020 mandates have been successfully challenged or rescinded, we must never forget that the repressive arm of government is just behind a curtain, waiting to strangle our rights," states Aaron Siri, ICAN's head of legal.
https://icandecide.org/press-release/breaking-news-ican-will-fund-legal-challenge-of-any-state-that-mandates-covid-19-vaccines-to-attend-school/
@takescienceback
"While most post-March 2020 mandates have been successfully challenged or rescinded, we must never forget that the repressive arm of government is just behind a curtain, waiting to strangle our rights," states Aaron Siri, ICAN's head of legal.
https://icandecide.org/press-release/breaking-news-ican-will-fund-legal-challenge-of-any-state-that-mandates-covid-19-vaccines-to-attend-school/
@takescienceback
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💥 New study confirms superiority of natural immunity!
"Previous natural infection was associated with lower incidence of SARS-CoV-2 infection, regardless of the variant, than mRNA primary-series vaccination.
Severe, critical, or fatal COVID-19 was rare in both the natural infection and vaccinated cohorts.
7123 SARS-CoV-2 infections were recorded in the BNT162b2 vaccinated cohort and 3583 reinfections were recorded in the matched natural infection cohort.
4282 SARS-CoV-2 infections were recorded in the mRNA-1273 vaccinated cohort and 2301 reinfections were recorded in the matched natural infection cohort."
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(22)00287-7/fulltext
@takescienceback
"Previous natural infection was associated with lower incidence of SARS-CoV-2 infection, regardless of the variant, than mRNA primary-series vaccination.
Severe, critical, or fatal COVID-19 was rare in both the natural infection and vaccinated cohorts.
7123 SARS-CoV-2 infections were recorded in the BNT162b2 vaccinated cohort and 3583 reinfections were recorded in the matched natural infection cohort.
4282 SARS-CoV-2 infections were recorded in the mRNA-1273 vaccinated cohort and 2301 reinfections were recorded in the matched natural infection cohort."
https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(22)00287-7/fulltext
@takescienceback
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Israeli researchers publish data in Nature journal that refutes the entire mass vaccination strategy.
"We show that while recent vaccination reduces Omicron viral load, its effect wanes rapidly. In contrast, a significantly slower waning rate is demonstrated for recovered COVID-19 individuals."
Ct values of those receiving 2 or 3 dose vaccination reaches a level similar to that of the unvaccinated by day 70, whereas Ct values of the previously infected in both variants demonstrates that viral load levels remain low well beyond 18 months.
"...this study mandates reevaluating the role of current vaccination campaigns in harnessing the potential infectivity of COVID-19"
https://www.nature.com/articles/s41467-022-33096-0
@takescienceback
"We show that while recent vaccination reduces Omicron viral load, its effect wanes rapidly. In contrast, a significantly slower waning rate is demonstrated for recovered COVID-19 individuals."
Ct values of those receiving 2 or 3 dose vaccination reaches a level similar to that of the unvaccinated by day 70, whereas Ct values of the previously infected in both variants demonstrates that viral load levels remain low well beyond 18 months.
"...this study mandates reevaluating the role of current vaccination campaigns in harnessing the potential infectivity of COVID-19"
https://www.nature.com/articles/s41467-022-33096-0
@takescienceback
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Hedley Rees is a known Big Pharma disruptor, fighting for patients against patent monopolies.
Hailing from Bridgend, UK, he is an advocate of modernization in the Pharma Industry. Rees operates a consultancy firm specializing in operations and supply chain management in life sciences and the author of INSIDE PHARMA Substack and “Supply Chain Management in the Drug Industry”.
He is challenging regulatory changes for Advanced Therapy Medicinal Products (ATMPs) in this FOI request to MHRA.
https://hedleyrees.substack.com/p/subject-foi-request-and-open-letter?utm_source=twitter&utm_campaign=auto_share&r=xoehy
@takescienceback
Hailing from Bridgend, UK, he is an advocate of modernization in the Pharma Industry. Rees operates a consultancy firm specializing in operations and supply chain management in life sciences and the author of INSIDE PHARMA Substack and “Supply Chain Management in the Drug Industry”.
He is challenging regulatory changes for Advanced Therapy Medicinal Products (ATMPs) in this FOI request to MHRA.
https://hedleyrees.substack.com/p/subject-foi-request-and-open-letter?utm_source=twitter&utm_campaign=auto_share&r=xoehy
@takescienceback
INSIDE PHARMA
Subject: FOI request and open letter to MHRA—please share far and wide...
...not something to be taken lightly!
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🔬 Ethical Science Council is now on Mastodon, a decentralized social media platform. It offers 'networking that's not for sale' through independent servers.
Find us at:
https://mstdn.science/@esc
Find us at:
https://mstdn.science/@esc
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Genetic Covid vaccines INCREASE the frequency of respiratory infections in children.
"Within 28 days after vaccination, some respiratory tract-related infections were reported with greater frequency in the mRNA-1273 group than in the placebo group. Events of pneumonia were reported by 0.3% and 0% of mRNA-1273 and placebo recipients, respectively. Respiratory syncytial virus (RSV) infection was reported by 0.4% and <0.1% of mRNA-1273 and placebo recipients, respectively."
https://www.fda.gov/media/159611/download#page=180
@takescienceback
"Within 28 days after vaccination, some respiratory tract-related infections were reported with greater frequency in the mRNA-1273 group than in the placebo group. Events of pneumonia were reported by 0.3% and 0% of mRNA-1273 and placebo recipients, respectively. Respiratory syncytial virus (RSV) infection was reported by 0.4% and <0.1% of mRNA-1273 and placebo recipients, respectively."
https://www.fda.gov/media/159611/download#page=180
@takescienceback
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Why Is Vaccine Guru Paul Offit Declining the COVID Booster?
News media’s main go-to source when they want to talk up or push vaccines, Dr. Paul Offit, attending physician at the Division of Infectious Diseases at Children’s Hospital of Philadelphia, has jumped off the COVID booster bandwagon and is refusing to get any more of the shots.
He not only disagrees with the current administration’s booster recommendations, but says the FDA, CDC and President Biden haven’t presented enough evidence that any protection the boosters might give would be “significantly greater” than not getting boosted.
According to The Philadelphia Inquirer, Offit thinks the shots are “grossly oversold.”
https://www.inquirer.com/health/coronavirus/paul-offit-philadelphia-covid-vaccine-bivalent-booster-20221108.html
@takescienceback
News media’s main go-to source when they want to talk up or push vaccines, Dr. Paul Offit, attending physician at the Division of Infectious Diseases at Children’s Hospital of Philadelphia, has jumped off the COVID booster bandwagon and is refusing to get any more of the shots.
He not only disagrees with the current administration’s booster recommendations, but says the FDA, CDC and President Biden haven’t presented enough evidence that any protection the boosters might give would be “significantly greater” than not getting boosted.
According to The Philadelphia Inquirer, Offit thinks the shots are “grossly oversold.”
https://www.inquirer.com/health/coronavirus/paul-offit-philadelphia-covid-vaccine-bivalent-booster-20221108.html
@takescienceback
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