How effective is the Monkeypox vaccine?
A new preprint shows, Low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals.
"Only in five out of eight sera MPXV neutralizing antibodies were detected 4 weeks after the first, but also the second vaccination." (See red box in image above)
"Antibody levels in some vaccinees increased after the second shot, but in general little increase in MPXV neutralization was observed after the second shot."
https://www.medrxiv.org/content/10.1101/2022.08.31.22279414v1
@takescienceback
A new preprint shows, Low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals.
"Only in five out of eight sera MPXV neutralizing antibodies were detected 4 weeks after the first, but also the second vaccination." (See red box in image above)
"Antibody levels in some vaccinees increased after the second shot, but in general little increase in MPXV neutralization was observed after the second shot."
https://www.medrxiv.org/content/10.1101/2022.08.31.22279414v1
@takescienceback
mRNA-LNP platform can pass down the acquired immune traits to their offspring!
This preprint study shows how the mRNA-LNP platform alters long-term adaptive immunity.
Conclusions:
1. The administration of mRNA-LNPs inhibits humoral responses to a second dose of the vaccine for at least several weeks.
2. Protection against fungal and viral infections is altered by the mRNA-LNPs platform.
3. The capacity of these vaccines to transmit protection trans-generationally is demonstrated, thus supporting the concept of Lamarckian inheritance in mammals.
https://www.biorxiv.org/content/10.1101/2022.03.16.484616v2
@takescienceback
This preprint study shows how the mRNA-LNP platform alters long-term adaptive immunity.
Conclusions:
1. The administration of mRNA-LNPs inhibits humoral responses to a second dose of the vaccine for at least several weeks.
2. Protection against fungal and viral infections is altered by the mRNA-LNPs platform.
3. The capacity of these vaccines to transmit protection trans-generationally is demonstrated, thus supporting the concept of Lamarckian inheritance in mammals.
https://www.biorxiv.org/content/10.1101/2022.03.16.484616v2
@takescienceback
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After months of litigation, the court has ordered that, by September 30, 2022, the CDC must produce the first batch of over 19 months’ worth of data collected from tens of millions of v-safe participants between December 14, 2020 and July 31, 2022.
https://www.icandecide.org/ican_press/breaking-news-ican-obtains-court-order-requiring-cdc-to-release-v-safe-data-that-includes-over-137-million-health-entries-made-after-covid-19-vaccines/
@takescienceback
https://www.icandecide.org/ican_press/breaking-news-ican-obtains-court-order-requiring-cdc-to-release-v-safe-data-that-includes-over-137-million-health-entries-made-after-covid-19-vaccines/
@takescienceback
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INFECTION ENHANCEMENT LURKS FOR THE VACCINATED
"Sera collected from mRNA-vaccinated individuals gradually exhibited dominance of ADE activity in a time-dependent manner.
It is noteworthy that ADE was observed only within a relatively narrow window of Ab and serum concentration.
This situation, i.e., observed ADE without neutralization at a low dilution of serum, is unfavorable for protection against infection.
Authors observed different behavior of Omicron in the ADE assay compared with the SARS-CoV-2 original strain."
https://www.nature.com/articles/s41598-022-19993-w
@takescienceback
"Sera collected from mRNA-vaccinated individuals gradually exhibited dominance of ADE activity in a time-dependent manner.
It is noteworthy that ADE was observed only within a relatively narrow window of Ab and serum concentration.
This situation, i.e., observed ADE without neutralization at a low dilution of serum, is unfavorable for protection against infection.
Authors observed different behavior of Omicron in the ADE assay compared with the SARS-CoV-2 original strain."
https://www.nature.com/articles/s41598-022-19993-w
@takescienceback
Nature
Reevaluation of antibody-dependent enhancement of infection in anti-SARS-CoV-2 therapeutic antibodies and mRNA-vaccine antisera…
Scientific Reports - Reevaluation of antibody-dependent enhancement of infection in anti-SARS-CoV-2 therapeutic antibodies and mRNA-vaccine antisera using FcR- and ACE2-positive cells
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⚖️ Administration of prophylactics and treatments is dependent on proper RISK-BENEFIT ANALYSIS!!
How many severe adverse events occurred to achieve rapidly waning vaccine effectiveness?
Effectiveness of 2 doses of Pfizer BNT162b against BA.4/5 was below 20% by 9 months post-vaccination and effectiveness of the 3rd dose rapidly declined.
The authors conclude, “…we found rapid waning of vaccine effectiveness against the current sublineages of the omicron variant with respect to protection against hospitalization. Evidence of rapid waning of durability indicates the need for regular boosting as early as 4 months after the last dose to maintain protection.”
⚠️ Published studies also demonstrate that mRNA vaccine antibodies have great potential for DISEASE ENHANCEMENT within a specific window of suboptimal antibody responses.
(see previous ESC post on Shimizu, J. et al. Reevaluation of antibody-dependent enhancement of infection in anti-SARS-CoV-2 therapeutic antibodies and mRNA-vaccine antisera using FcR- and ACE2-positive cells. Sci Rep 12, 15612 (2022))
https://www.nejm.org/doi/pdf/10.1056/NEJMc2210093
@takescienceback
How many severe adverse events occurred to achieve rapidly waning vaccine effectiveness?
Effectiveness of 2 doses of Pfizer BNT162b against BA.4/5 was below 20% by 9 months post-vaccination and effectiveness of the 3rd dose rapidly declined.
The authors conclude, “…we found rapid waning of vaccine effectiveness against the current sublineages of the omicron variant with respect to protection against hospitalization. Evidence of rapid waning of durability indicates the need for regular boosting as early as 4 months after the last dose to maintain protection.”
⚠️ Published studies also demonstrate that mRNA vaccine antibodies have great potential for DISEASE ENHANCEMENT within a specific window of suboptimal antibody responses.
(see previous ESC post on Shimizu, J. et al. Reevaluation of antibody-dependent enhancement of infection in anti-SARS-CoV-2 therapeutic antibodies and mRNA-vaccine antisera using FcR- and ACE2-positive cells. Sci Rep 12, 15612 (2022))
https://www.nejm.org/doi/pdf/10.1056/NEJMc2210093
@takescienceback
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A federal judge is siding with a group of Republican Attorney Generals in blocking a COVID-19 mandate for Head Start.
“Although vaccines arguably serve the public interest, the liberty interests of individuals mandated to take the COVID-19 vaccine outweigh any interest generated by the mandatory administration of vaccines,” wrote Judge Doughty in issuing the ruling.
@takescienceback
“Although vaccines arguably serve the public interest, the liberty interests of individuals mandated to take the COVID-19 vaccine outweigh any interest generated by the mandatory administration of vaccines,” wrote Judge Doughty in issuing the ruling.
@takescienceback
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Renz Law and MAFA have compiled an Executive Summary on the Origin of SARS-CoV-2. There is a call for immediate bipartisan investigation that will support prosecutions.
Declarations by American patriot Andrew Huff, EcoHealth Alliance whistleblower, are included.
Conclusions are outlined starting on Page 28: The Creation of SARS-CoV-2 Was Funded by NIH, NIAID, and EcoHealth Alliance and Took Place in a Lab
https://renz-law.com/wp-content/uploads/Senator-Johnson-Final.pdf
@takescienceback
Declarations by American patriot Andrew Huff, EcoHealth Alliance whistleblower, are included.
Conclusions are outlined starting on Page 28: The Creation of SARS-CoV-2 Was Funded by NIH, NIAID, and EcoHealth Alliance and Took Place in a Lab
https://renz-law.com/wp-content/uploads/Senator-Johnson-Final.pdf
@takescienceback
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Forwarded from PANDA | Science. Sense. Society.
Testing for a respiratory virus infection shouldn't change how a doctor treats an individual, since treatment would be symptom-based and mostly supportive. C19 is the first communicable disease for which a person with no signs or symptoms of illness may be classified as a confirmed case.
What role did the "gold standard" PCR test play in influencing the global perspective on the pandemic?
https://www.pandata.org/pcr-testing-skewed-and-corrupted-data-on-sars-cov-2-infection-and-death-rates/
What role did the "gold standard" PCR test play in influencing the global perspective on the pandemic?
https://www.pandata.org/pcr-testing-skewed-and-corrupted-data-on-sars-cov-2-infection-and-death-rates/
PANDA
PCR testing skewed and corrupted data on SARS-CoV-2 infection and death rates - PANDA
Traditionally clinicians do not test for respiratory viruses because testing does not inform patient treatment. In the case of the widespread PCR testing seen during the Covid-19 pandemic, the results should be evaluated in the context of clinical symptoms…
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"In individuals aged greater than 30, the rate of a positive COVID-19 test is higher in vaccinated individuals compared to unvaccinated."
New data from the UK:
https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&cad=rja&uact=8&ved=2ahUKEwj9vsexjND6AhVBhf0HHVmyC5gQFnoECBMQAQ&url=https%3A%2F%2Fassets.publishing.service.gov.uk%2Fgovernment%2Fuploads%2Fsystem%2Fuploads%2Fattachment_data%2Ffile%2F1027511%2FVaccine-surveillance-report-week-42.pdf&usg=AOvVaw20m3Vk8lU7gR_QQchzdL8R
Tx t.me/DrJohnB
New data from the UK:
https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&cad=rja&uact=8&ved=2ahUKEwj9vsexjND6AhVBhf0HHVmyC5gQFnoECBMQAQ&url=https%3A%2F%2Fassets.publishing.service.gov.uk%2Fgovernment%2Fuploads%2Fsystem%2Fuploads%2Fattachment_data%2Ffile%2F1027511%2FVaccine-surveillance-report-week-42.pdf&usg=AOvVaw20m3Vk8lU7gR_QQchzdL8R
Tx t.me/DrJohnB
Ethical Science Council
"In individuals aged greater than 30, the rate of a positive COVID-19 test is higher in vaccinated individuals compared to unvaccinated." New data from the UK: https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&cad=rja&uact=8&ved=2ahUKEwj9vse…
Week 42 from UK HSA corresponds to 24 October 2021, nearly a year ego.
Why did HSA stop reporting these numbers?
Infections in the vaccinated have certainly only climbed in the year since data was tabulated.
Transparency appears elusive.
Why did HSA stop reporting these numbers?
Infections in the vaccinated have certainly only climbed in the year since data was tabulated.
Transparency appears elusive.
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Bivalent booster vaccination is authorized for administration at least two months following completion of primary or booster vaccination in children down to five years of age.
https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-moderna-and-pfizer-biontech-bivalent-covid-19-vaccines
@takescienceback
https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-moderna-and-pfizer-biontech-bivalent-covid-19-vaccines
@takescienceback
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Dear Principal.pdf
179.8 KB
‼️ TAKE ACTION
Help Ethical Science Council share this letter so that parents can confidently affirm their stance against Covid genetic vaccination and preserve children from state overreach.
The U.S. Supreme Court has described parental rights as “beyond debate as an enduring American tradition”.
@takescienceback
Help Ethical Science Council share this letter so that parents can confidently affirm their stance against Covid genetic vaccination and preserve children from state overreach.
The U.S. Supreme Court has described parental rights as “beyond debate as an enduring American tradition”.
@takescienceback
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History will reveal gross negligence on the push for childhood vaccination for Covid.
The risk versus benefit scenario clearly does NOT support use of genetic vaccines for SARS-CoV-2, most especially in children. Long-term outcomes of resolved myocarditis are historically associated with decreased life span.
"Close to 90% of those aged 3–17 are fully immunized in Chile, compared with 28% of kids aged 5–11 in New Zealand and 3% of the same age group in the Netherlands (see ‘Patchy uptake’)."
Let's track closely the childhood all-cause mortality rate among these countries.
https://www.nature.com/articles/d41586-022-03203-8
@takescienceback
The risk versus benefit scenario clearly does NOT support use of genetic vaccines for SARS-CoV-2, most especially in children. Long-term outcomes of resolved myocarditis are historically associated with decreased life span.
"Close to 90% of those aged 3–17 are fully immunized in Chile, compared with 28% of kids aged 5–11 in New Zealand and 3% of the same age group in the Netherlands (see ‘Patchy uptake’)."
Let's track closely the childhood all-cause mortality rate among these countries.
https://www.nature.com/articles/d41586-022-03203-8
@takescienceback
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Rates of SARS-CoV-2 infection and Covid-19 are HIGHER in the Bivalent Omicron/Wuhan Spike vaccinated (mRNA1273.214) group as compared to original Wuhan Spike vaccination (mRNA-1273).
https://www.nejm.org/doi/full/10.1056/NEJMoa2208343
@takescienceback
https://www.nejm.org/doi/full/10.1056/NEJMoa2208343
@takescienceback
📣 IT IS TIME FOR YOU TO STAND UP!
The CDC is planning to discuss adding Covid vaccination to the required immunization schedule for school age children in a meeting on October 19th. Follow the link below to make a comment as the period to do so ends the day of meeting. Please share this with everyone you know to protect our kids!
https://www.regulations.gov/document/CDC-2022-0111-0001
Ethical Science Council has armed parents with a fully referenced letter to print, sign and turn into your child's school. See the post on Oct 13 in our channel. It's best to solidify your stance and turn the letter in BEFORE any requirements are added to the childhood immunization schedule. Play offense instead of defense!
@takescienceback
The CDC is planning to discuss adding Covid vaccination to the required immunization schedule for school age children in a meeting on October 19th. Follow the link below to make a comment as the period to do so ends the day of meeting. Please share this with everyone you know to protect our kids!
https://www.regulations.gov/document/CDC-2022-0111-0001
Ethical Science Council has armed parents with a fully referenced letter to print, sign and turn into your child's school. See the post on Oct 13 in our channel. It's best to solidify your stance and turn the letter in BEFORE any requirements are added to the childhood immunization schedule. Play offense instead of defense!
@takescienceback
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🚨 LOCK STEP
Global coordinated timing to push Covid genetic vaccines into children?
The European Medicines Agency has recommended including the use in children aged 6 months to 4 years for Comirnaty and use in children aged 6 months to 5 years for Spikevax.
https://www.ema.europa.eu/en/news/ema-recommends-approval-comirnaty-spikevax-covid-19-vaccines-children-6-months-age
This on the same day that CDC Votes 15-0 to add the vaccine to the "Vaccines for Children" (VFC) Program in the U.S. VFC is a federally funded program that provides vaccines at no cost to children who might not otherwise be vaccinated because of inability to pay. The CDC buys vaccine at a discounted rate for distribution to registered VFC providers.
There is another vote tomorrow morning on ACIP's recommendation to add the Covid genetic vaccine to the U.S. child immunization schedule.
Of note, 4 ACIP members regularly engage in political advocacy on Twitter. Here’s but a small sample size of the political activism of committee members, which again, are tasked with the enormous responsibility of endorsing the safety and efficacy of children’s pharmaceutical products.
https://open.substack.com/pub/dossier/p/impeach-him-again-cdc-advisory-committee?utm_source=direct&r=q9aux&utm_campaign=post&utm_medium=web
@takescienceback
Global coordinated timing to push Covid genetic vaccines into children?
The European Medicines Agency has recommended including the use in children aged 6 months to 4 years for Comirnaty and use in children aged 6 months to 5 years for Spikevax.
https://www.ema.europa.eu/en/news/ema-recommends-approval-comirnaty-spikevax-covid-19-vaccines-children-6-months-age
This on the same day that CDC Votes 15-0 to add the vaccine to the "Vaccines for Children" (VFC) Program in the U.S. VFC is a federally funded program that provides vaccines at no cost to children who might not otherwise be vaccinated because of inability to pay. The CDC buys vaccine at a discounted rate for distribution to registered VFC providers.
There is another vote tomorrow morning on ACIP's recommendation to add the Covid genetic vaccine to the U.S. child immunization schedule.
Of note, 4 ACIP members regularly engage in political advocacy on Twitter. Here’s but a small sample size of the political activism of committee members, which again, are tasked with the enormous responsibility of endorsing the safety and efficacy of children’s pharmaceutical products.
https://open.substack.com/pub/dossier/p/impeach-him-again-cdc-advisory-committee?utm_source=direct&r=q9aux&utm_campaign=post&utm_medium=web
@takescienceback
The Dossier
‘Impeach him again’: CDC advisory committee plagued with political activism
Committee is set to green light shots for kids with no clinical data.
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Japanese investigators determine the risk of myocarditis from Covid genetic vaccines has been underestimated.
"SARS-CoV-2 vaccination was associated with higher risk of myocarditis death, not only in young adults but also in all age groups including the elderly. SARS-CoV-2 vaccination may be more serious than that reported previously."
https://www.medrxiv.org/content/10.1101/2022.10.13.22281036v1
@takescienceback
"SARS-CoV-2 vaccination was associated with higher risk of myocarditis death, not only in young adults but also in all age groups including the elderly. SARS-CoV-2 vaccination may be more serious than that reported previously."
https://www.medrxiv.org/content/10.1101/2022.10.13.22281036v1
@takescienceback
medRxiv
SARS-CoV-2 vaccine and increased myocarditis mortality risk: A population based comparative study in Japan
Objective To investigate the association between SARS-CoV-2 vaccination and myocarditis death
Design Population based comparative mortality study
Setting Japan
Participants Vaccinated population was 99 834 543 individuals aged 12 years and older who have…
Design Population based comparative mortality study
Setting Japan
Participants Vaccinated population was 99 834 543 individuals aged 12 years and older who have…
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Misinterpretation of chimeric virus study at Boston University
https://www.biorxiv.org/content/10.1101/2022.10.13.512134v1.full
Purpose: To determine the contribution of Spike to pathogenicity of SARS-CoV-2
Approach: "We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 and compared this virus with the naturally circulating Omicron variant."
Details: In hACE2 mice, Wuhan (WT) is 100% lethal and Omicron is nonlethal. When Omicron Spike replaces Wuhan Spike, pathogenicity decreases from 100% to 80%, thus an attenuated strain of Wuhan was generated. This is not a gain of function but rather a LOSS of function.
Conclusion: "Major determinants of viral pathogenicity reside outside of S"
What is the necessity of chimeric virus research and the unethical approach to creating new recombinant viruses with unknown pathogenicity and outbreak potential? Should the U.S. have lifted the ban on Gain of Function research in 2017?
@takescienceback
https://www.biorxiv.org/content/10.1101/2022.10.13.512134v1.full
Purpose: To determine the contribution of Spike to pathogenicity of SARS-CoV-2
Approach: "We generated chimeric recombinant SARS-CoV-2 encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 and compared this virus with the naturally circulating Omicron variant."
Details: In hACE2 mice, Wuhan (WT) is 100% lethal and Omicron is nonlethal. When Omicron Spike replaces Wuhan Spike, pathogenicity decreases from 100% to 80%, thus an attenuated strain of Wuhan was generated. This is not a gain of function but rather a LOSS of function.
Conclusion: "Major determinants of viral pathogenicity reside outside of S"
What is the necessity of chimeric virus research and the unethical approach to creating new recombinant viruses with unknown pathogenicity and outbreak potential? Should the U.S. have lifted the ban on Gain of Function research in 2017?
@takescienceback
The Supreme Court of New York finds vaccination mandates unconstitutional declaring them arbitrary and capricious.
https://iapps.courts.state.ny.us/fbem/DocumentDisplayServlet?documentId=JK5E3gx5XV1/ku37jnWR_PLUS_w==&system=prod
@takescienceback
https://iapps.courts.state.ny.us/fbem/DocumentDisplayServlet?documentId=JK5E3gx5XV1/ku37jnWR_PLUS_w==&system=prod
@takescienceback
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In July 2021 the US FDA quietly disclosed findings of a potential increase in four types of serious adverse events in elderly people who had had Pfizer’s covid-19 vaccine: acute myocardial infarction, disseminated intravascular coagulation, immune thrombocytopenia, and pulmonary embolism.
The unadjusted relative risk ratio estimates originally found for the four serious adverse events ranged from 42% to 91% increased risk. More than a year later, however, the status and results of the follow-up study are unknown.
"To keep this information from the scientific community and prevent us from analysing it ourselves, is irresponsible. It presumes that these organisations are perfect and cannot benefit from independent scrutiny,” says Joseph Fraiman, an emergency medicine physician in New Orleans.
https://www.bmj.com/content/379/bmj.o2527
@takescienceback
The unadjusted relative risk ratio estimates originally found for the four serious adverse events ranged from 42% to 91% increased risk. More than a year later, however, the status and results of the follow-up study are unknown.
"To keep this information from the scientific community and prevent us from analysing it ourselves, is irresponsible. It presumes that these organisations are perfect and cannot benefit from independent scrutiny,” says Joseph Fraiman, an emergency medicine physician in New Orleans.
https://www.bmj.com/content/379/bmj.o2527
@takescienceback
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