"Surprisingly, 2 or more doses of vaccine were associated with a slightly higher probability of reinfection compared with 1 dose or less."
Some of us aren't surprised.
@takescienceback
https://jamanetwork.com/journals/jamanetworkopen/article-abstract/2794886
Some of us aren't surprised.
@takescienceback
https://jamanetwork.com/journals/jamanetworkopen/article-abstract/2794886
A judge in the Eastern District of Virginia has ordered the National Institutes of Health (NIH) to provide unredacted copies of certain documents to ascertain whether NIH improperly redacted them.
This ruling pertains to a lawsuit filed by Empower Oversight, a watchdog group seeking information on the NIHβs deletion of Covid-19 genetic data at the request of a Chinese researcher.
https://empowr.us/wp-content/uploads/2022/08/55_Order-denying-unseal-and-SJ-abeyance.pdf
https://empowr.us/wp-content/uploads/2022/07/41_Opp-to-SJ_Empower-Oversight.pdf
@takescienceback
This ruling pertains to a lawsuit filed by Empower Oversight, a watchdog group seeking information on the NIHβs deletion of Covid-19 genetic data at the request of a Chinese researcher.
https://empowr.us/wp-content/uploads/2022/08/55_Order-denying-unseal-and-SJ-abeyance.pdf
https://empowr.us/wp-content/uploads/2022/07/41_Opp-to-SJ_Empower-Oversight.pdf
@takescienceback
π₯7
"In this cohort study of 210 adults with evidence of seroconversion during a regional Omicron variant surge, 56% reported being unaware of any recent Omicron variant infection."
More than half the individuals in the study did not know they were infected. SARS-CoV-2 causes a mild, endemic cold and variants have trended toward less disease over time.
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2795246
@takescienceback
More than half the individuals in the study did not know they were infected. SARS-CoV-2 causes a mild, endemic cold and variants have trended toward less disease over time.
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2795246
@takescienceback
π2
Children still show signs of heart damage at 3 month follow up after vaccine induced myocarditis.
"Most patients still had a small amount of late gadolinium enhancement, the clinical significance of which is yet to be determined."
Children do NOT need the Covid genetic vaccine!
@takescienceback
https://link.springer.com/article/10.1007/s00431-022-04482-z
"Most patients still had a small amount of late gadolinium enhancement, the clinical significance of which is yet to be determined."
Children do NOT need the Covid genetic vaccine!
@takescienceback
https://link.springer.com/article/10.1007/s00431-022-04482-z
π6
β£οΈ BOOSTERS ARE PROMOTING COVID DEATHS!
Since June 1, 2022, when the BA.5 variant took over circulation in Europe, the trend of booster doses protecting against deaths has reversed.
https://ourworldindata.org/
Image adapted from:
https://igorchudov.substack.com/p/boosters-now-promote-covid-deaths
@takescienceback
Since June 1, 2022, when the BA.5 variant took over circulation in Europe, the trend of booster doses protecting against deaths has reversed.
https://ourworldindata.org/
Image adapted from:
https://igorchudov.substack.com/p/boosters-now-promote-covid-deaths
@takescienceback
π₯4
NATURE Journal admits to Spike induced damage!
COVID Vaccine encoded Spike is almost identical to native virus Spike. Spike has been linked to amyloid fibril formation and likely the caustive agent of micro-clots.
"When they added the Spike protein to plasma from healthy volunteers in the laboratory, that alone was enough to prompt formation of these abnormal clots."
https://www.nature.com/articles/d41586-022-02286-7
@takescienceback
COVID Vaccine encoded Spike is almost identical to native virus Spike. Spike has been linked to amyloid fibril formation and likely the caustive agent of micro-clots.
"When they added the Spike protein to plasma from healthy volunteers in the laboratory, that alone was enough to prompt formation of these abnormal clots."
https://www.nature.com/articles/d41586-022-02286-7
@takescienceback
Nature
Could tiny blood clots cause long COVIDβs puzzling symptoms?
Nature - Scientists debate evidence for a micro-clot hypothesis that has some people pursuing potentially risky treatments.
π6π€―1
The north Indian state of 231 million people eradicated COVID with an ivermectin treatment program, representing one of the greatest public health achievements in history. It was kept a global secret.
https://pierrekory.substack.com/p/the-miracle-not-heard-around-the
@takescienceback
https://pierrekory.substack.com/p/the-miracle-not-heard-around-the
@takescienceback
π10
Covid vaccine mandates ruled unlawful for government workers, but mandates remain unchallenged for school children!
"The vaccine mandate for city government workers in Washington, D.C., is unlawful, D.C. Superior Court Judge Maurice Ross ruled Thursday."
_
"Beginning in the 2022-23 school year, the COVID-19 vaccine is required for school enrollment and attendance in the District of Columbia for all students who are of an age for which there is a COVID-19 vaccination fully approved by the US Food and Drug Administration (FDA). As of July 8, 2022, there is a fully approved COVID-19 vaccine for individuals age 12 and older."
https://www.newsnationnow.com/health/coronavirus/vaccine/judge-vaccine-mandate-for-d-c-gov-workers-unlawful/
https://osse.dc.gov/page/district-columbia-immunization-attendance-policy
@takescienceback
"The vaccine mandate for city government workers in Washington, D.C., is unlawful, D.C. Superior Court Judge Maurice Ross ruled Thursday."
_
"Beginning in the 2022-23 school year, the COVID-19 vaccine is required for school enrollment and attendance in the District of Columbia for all students who are of an age for which there is a COVID-19 vaccination fully approved by the US Food and Drug Administration (FDA). As of July 8, 2022, there is a fully approved COVID-19 vaccine for individuals age 12 and older."
https://www.newsnationnow.com/health/coronavirus/vaccine/judge-vaccine-mandate-for-d-c-gov-workers-unlawful/
https://osse.dc.gov/page/district-columbia-immunization-attendance-policy
@takescienceback
π₯6π€―3
βοΈ This type of early treatment should have been used from early 2020
"We briefly describe the pathogenic mechanisms underlying the inflammatory processes of early stage COVID-19 and discuss the rationale for using non-steroidal anti-inflammatory drugs (NSAIDs), as well as evidence regarding their risk-to-benefit balance in the home and community setting.
The findings from these studies are promising and point to a crucial role of NSAIDs for the at-home management of people with initial COVID-19 symptoms."
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00433-9/fulltext
@takescienceback
"We briefly describe the pathogenic mechanisms underlying the inflammatory processes of early stage COVID-19 and discuss the rationale for using non-steroidal anti-inflammatory drugs (NSAIDs), as well as evidence regarding their risk-to-benefit balance in the home and community setting.
The findings from these studies are promising and point to a crucial role of NSAIDs for the at-home management of people with initial COVID-19 symptoms."
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00433-9/fulltext
@takescienceback
βConclusions: We found no significant differences in SARS-CoV-2 transmission due to Face Covering Mask mandates in Catalonian schools."
https://adc.bmj.com/content/early/2022/08/23/archdischild-2022-324172
https://adc.bmj.com/content/early/2022/08/23/archdischild-2022-324172
π6β€4
Summary of the Public Assessment Report
Authorisation for Temporary Supply, COVID-19 mRNA Vaccine BNT162b2 (BNT162b2 RNA) concentrate for solution for injection
Department of Health and Social Care (DHSC), Pfizer Limited & BioNTech Manufacturing, GmbH.
https://www.gov.uk/government/publications/regulatory-approval-of-pfizer-biontech-vaccine-for-covid-19/summary-public-assessment-report-for-pfizerbiontech-covid-19-vaccine
@takescienceback
Authorisation for Temporary Supply, COVID-19 mRNA Vaccine BNT162b2 (BNT162b2 RNA) concentrate for solution for injection
Department of Health and Social Care (DHSC), Pfizer Limited & BioNTech Manufacturing, GmbH.
https://www.gov.uk/government/publications/regulatory-approval-of-pfizer-biontech-vaccine-for-covid-19/summary-public-assessment-report-for-pfizerbiontech-covid-19-vaccine
@takescienceback
π€¬5π1
"The results showed the Pfizer and Moderna both exhibited an absolute risk increase of serious adverse events of special interest (combined, 1 per 800 vaccinated), raising concerns that mRNA vaccines are associated with more harm than initially estimated at the time of emergency authorization."
https://www.bmj.com/content/378/bmj.o1731/rr-0
@takescienceback
https://www.bmj.com/content/378/bmj.o1731/rr-0
@takescienceback
π8π1
SARS-COV-2 was not a novel virus to the immune system!
"Our results indicate that the high levels of HCoV-OC43-nucleocapsid antibodies, as an indicator of a recent infection, are associated with protection against SARS-CoV-2 infection"
https://www.cell.com/iscience/fulltext/S2589-0042(22)01377-3
@takescienceback
"Our results indicate that the high levels of HCoV-OC43-nucleocapsid antibodies, as an indicator of a recent infection, are associated with protection against SARS-CoV-2 infection"
https://www.cell.com/iscience/fulltext/S2589-0042(22)01377-3
@takescienceback
iScience
Recent infection with HCoV-OC43 may be associated with protection against SARS-CoV-2 infection
Molecular physiology; Immunology; Virology
π6
How effective is the Monkeypox vaccine?
A new preprint shows, Low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals.
"Only in five out of eight sera MPXV neutralizing antibodies were detected 4 weeks after the first, but also the second vaccination." (See red box in image above)
"Antibody levels in some vaccinees increased after the second shot, but in general little increase in MPXV neutralization was observed after the second shot."
https://www.medrxiv.org/content/10.1101/2022.08.31.22279414v1
@takescienceback
A new preprint shows, Low levels of monkeypox virus neutralizing antibodies after MVA-BN vaccination in healthy individuals.
"Only in five out of eight sera MPXV neutralizing antibodies were detected 4 weeks after the first, but also the second vaccination." (See red box in image above)
"Antibody levels in some vaccinees increased after the second shot, but in general little increase in MPXV neutralization was observed after the second shot."
https://www.medrxiv.org/content/10.1101/2022.08.31.22279414v1
@takescienceback
mRNA-LNP platform can pass down the acquired immune traits to their offspring!
This preprint study shows how the mRNA-LNP platform alters long-term adaptive immunity.
Conclusions:
1. The administration of mRNA-LNPs inhibits humoral responses to a second dose of the vaccine for at least several weeks.
2. Protection against fungal and viral infections is altered by the mRNA-LNPs platform.
3. The capacity of these vaccines to transmit protection trans-generationally is demonstrated, thus supporting the concept of Lamarckian inheritance in mammals.
https://www.biorxiv.org/content/10.1101/2022.03.16.484616v2
@takescienceback
This preprint study shows how the mRNA-LNP platform alters long-term adaptive immunity.
Conclusions:
1. The administration of mRNA-LNPs inhibits humoral responses to a second dose of the vaccine for at least several weeks.
2. Protection against fungal and viral infections is altered by the mRNA-LNPs platform.
3. The capacity of these vaccines to transmit protection trans-generationally is demonstrated, thus supporting the concept of Lamarckian inheritance in mammals.
https://www.biorxiv.org/content/10.1101/2022.03.16.484616v2
@takescienceback
π±9β€1π1π₯1
After months of litigation, the court has ordered that, by September 30, 2022, the CDC must produce the first batch of over 19 monthsβ worth of data collected from tens of millions of v-safe participants between December 14, 2020 and July 31, 2022.
https://www.icandecide.org/ican_press/breaking-news-ican-obtains-court-order-requiring-cdc-to-release-v-safe-data-that-includes-over-137-million-health-entries-made-after-covid-19-vaccines/
@takescienceback
https://www.icandecide.org/ican_press/breaking-news-ican-obtains-court-order-requiring-cdc-to-release-v-safe-data-that-includes-over-137-million-health-entries-made-after-covid-19-vaccines/
@takescienceback
π₯11β€4π3
INFECTION ENHANCEMENT LURKS FOR THE VACCINATED
"Sera collected from mRNA-vaccinated individuals gradually exhibited dominance of ADE activity in a time-dependent manner.
It is noteworthy that ADE was observed only within a relatively narrow window of Ab and serum concentration.
This situation, i.e., observed ADE without neutralization at a low dilution of serum, is unfavorable for protection against infection.
Authors observed different behavior of Omicron in the ADE assay compared with the SARS-CoV-2 original strain."
https://www.nature.com/articles/s41598-022-19993-w
@takescienceback
"Sera collected from mRNA-vaccinated individuals gradually exhibited dominance of ADE activity in a time-dependent manner.
It is noteworthy that ADE was observed only within a relatively narrow window of Ab and serum concentration.
This situation, i.e., observed ADE without neutralization at a low dilution of serum, is unfavorable for protection against infection.
Authors observed different behavior of Omicron in the ADE assay compared with the SARS-CoV-2 original strain."
https://www.nature.com/articles/s41598-022-19993-w
@takescienceback
Nature
Reevaluation of antibody-dependent enhancement of infection in anti-SARS-CoV-2 therapeutic antibodies and mRNA-vaccine antiseraβ¦
Scientific Reports - Reevaluation of antibody-dependent enhancement of infection in anti-SARS-CoV-2 therapeutic antibodies and mRNA-vaccine antisera using FcR- and ACE2-positive cells
π9
βοΈ Administration of prophylactics and treatments is dependent on proper RISK-BENEFIT ANALYSIS!!
How many severe adverse events occurred to achieve rapidly waning vaccine effectiveness?
Effectiveness of 2 doses of Pfizer BNT162b against BA.4/5 was below 20% by 9 months post-vaccination and effectiveness of the 3rd dose rapidly declined.
The authors conclude, ββ¦we found rapid waning of vaccine effectiveness against the current sublineages of the omicron variant with respect to protection against hospitalization. Evidence of rapid waning of durability indicates the need for regular boosting as early as 4 months after the last dose to maintain protection.β
β οΈ Published studies also demonstrate that mRNA vaccine antibodies have great potential for DISEASE ENHANCEMENT within a specific window of suboptimal antibody responses.
(see previous ESC post on Shimizu, J. et al. Reevaluation of antibody-dependent enhancement of infection in anti-SARS-CoV-2 therapeutic antibodies and mRNA-vaccine antisera using FcR- and ACE2-positive cells. Sci Rep 12, 15612 (2022))
https://www.nejm.org/doi/pdf/10.1056/NEJMc2210093
@takescienceback
How many severe adverse events occurred to achieve rapidly waning vaccine effectiveness?
Effectiveness of 2 doses of Pfizer BNT162b against BA.4/5 was below 20% by 9 months post-vaccination and effectiveness of the 3rd dose rapidly declined.
The authors conclude, ββ¦we found rapid waning of vaccine effectiveness against the current sublineages of the omicron variant with respect to protection against hospitalization. Evidence of rapid waning of durability indicates the need for regular boosting as early as 4 months after the last dose to maintain protection.β
β οΈ Published studies also demonstrate that mRNA vaccine antibodies have great potential for DISEASE ENHANCEMENT within a specific window of suboptimal antibody responses.
(see previous ESC post on Shimizu, J. et al. Reevaluation of antibody-dependent enhancement of infection in anti-SARS-CoV-2 therapeutic antibodies and mRNA-vaccine antisera using FcR- and ACE2-positive cells. Sci Rep 12, 15612 (2022))
https://www.nejm.org/doi/pdf/10.1056/NEJMc2210093
@takescienceback
π8β€1