In alternative pathway of activation of complement, a molecule of which of the following proteins must be bound to a target cell?
Anonymous Quiz
83%
C3b
13%
C3a
4%
C1
0%
C2b
In the alternative complement pathway, activation is triggered by:
Anonymous Quiz
14%
Circulating immunoglobulin IgM or IgG
73%
Bacterial endotoxin
5%
CD40L
9%
FAS ligand
In the alternative complement pathway
Anonymous Quiz
14%
- it is initiated by antigen-antibody complex
0%
The nine complement components are involved
5%
No role for properdin
81%
It is one of the innate defensive mechanisms
In the alternative pathway, the following are true EXCEPT:
Anonymous Quiz
5%
Properdin is needed for activation of C3
5%
Microbial components like endotoxin are needed for initiation
10%
Only C3,5,6,7,8 & 9 are involved
80%
. It is considered part of acquired (specific) Immunity
Which outcome is expected to occur after complement activation
Anonymous Quiz
10%
Agglutination
5%
Neutralization
81%
Opsonization
5%
T-cell proliferation
All of the following are true about complement EXCEPT:
Anonymous Quiz
5%
it is formed of nine basic components
74%
It is heat-stable
5%
it is produced mainly by the liver
16%
It is activated by IgM
Which of the following statements about complement is true;
Anonymous Quiz
6%
They are heat stable proteins
29%
They are activated in the liver
0%
The classic pathway is a part of innate immunity
65%
Properdin is required for complement activation via the alternative pathway
Which of the following describes a group of serum proteins that can lyse Gram-negative bacteria that have antibody on their surface?
Anonymous Quiz
39%
Complement
6%
Lactoferrin
28%
Lysozyme
28%
Interferon (IFN) gamma
All of the following are functions of activated complement EXCEPT:
Anonymous Quiz
25%
Bacterial lysis
0%
Opsonization
69%
Interference with viral replication
6%
Immune complex clearance
Regarding the classical complement pathway, all is true EXCEPT:
Anonymous Quiz
0%
It is involved in acquired (specific) immunity
7%
Antibodies are needed for activation of C1
86%
Microbial components like endotoxin are needed for initiation
7%
All components from C1-C9 are involved
The complement component which attaches to Fc portion of IgM is:
Anonymous Quiz
0%
C1a
67%
C3B
0%
C4b2
0%
C5
33%
C1
Transfer of antibodies from mother to child through colostrum is a form of
Anonymous Quiz
100%
Natural passive immunity
0%
Artificial passive immunity
0%
Natural active immunity
0%
Innate immunity, since it occurs naturally in all newborns
Treatment with gamma globulin is considered
Anonymous Quiz
11%
Artificial active immunity
83%
Artificial passive immunity
0%
Natural active immunity
6%
Natural passive immunity
Immunity following injection of an antitoxin is a form of
Anonymous Quiz
0%
Cell mediated immunity
7%
Natural passive immunity
60%
Artificial passive immunity
33%
Artificial active immunity
Concerning active immunity, which statement is True:
Anonymous Quiz
93%
It includes development of an immunological memory
7%
It is present in all individuals, against all microorganisms.
0%
Its onset starts immediately after infection
0%
The duration of its protection is usually short.
immunity following administration of vaccines is a form of:
Anonymous Quiz
6%
Natural passive immunity
11%
Artificial passive immunity
6%
Natural active immunity
78%
Artificial active immunity
Which protection would be provided by injection of a toxoid
Anonymous Quiz
0%
Natural passive immunity
38%
Artificial passive immunity.
0%
Natural active immunity
63%
Artificial active immunity