Vesicular peptides are generated from all of the following EXCEPT
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25%
Extracellular bacteria
19%
Intracellular bacteria
0%
Bacterial toxins
56%
Viruses living inside the cell
Extracellular bacteria are presented to T. cells in association with:
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12%
MHC class I
76%
MHC class Il
12%
Fc receptors
0%
C3b receptors
Peptides derived from a bacterial toxin are typically:
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6%
Presented on MHC I molecules to T helper cells
24%
Presented on MHC I molecules to T cytotoxic cells
65%
Present in the vesicular system
6%
Considered endogenous antigens
Which statement is INCORRECT?
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5%
MHC I molecule binds peptides and is recognized by TCR and CD8
16%
MHC II molecule binds peptides and is recognized by TCR and CD4
79%
Recognition of peptides carried on MHCII molecules on acell result in cytotoxic killing of that cell
0%
One cell may have both MHCI and MHC II molecules
Peptides arising in the vesicular system are presented to:
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6%
Cytotoxic T cells
88%
Helper T cells
6%
Both
0%
Neither
As regard peptides arising in the cytosol or in the vesicular system:
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75%
Cytosol peptides are carried on MHC I molecules
13%
Vesicular peptides are carried on MHC I molecules
6%
Cytosol peptides are presented to helper T cells
6%
Vesicular peptides are presented to cytotoxic T cells
The role of T cell in the immune response includes:
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88%
Recognition of epitopes presented with MHC molecules on cell surfaces
0%
Antigen presentation
0%
Phagocytosis
13%
Complement activation
During the process of antigen recognition, the second signal needed for T cell activation is delivered when:
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24%
CD40 ligand binds to CD40 molecule
6%
CD4 binds to MHCII molecule
6%
CD8 binds to MHCI molecule
65%
CD28 binds to B7 molecule
Which statement about the primary immune response is Not true
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13%
Requires two signals for activation Tealis
0%
Produces effector T cells
13%
Produces memory T cells
73%
Produces naive T cells
One of the following is a pro-inflammatory cytokine:
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14%
TGF - a
64%
TNF - ß
5%
IL 4
18%
IL 5
Th1 cells are characterized by:
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6%
They produce IL-4
6%
They are activated by IL-4
6%
Their development is promoted by IL-4
81%
Their development is inhibited by IL 4
All of the following statements about Th1 cells are true EXCEPT:
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15%
They produce IL-2
8%
Their development is promoted by IFN-y
15%
Their development is inhibited by IL-4 and IL-10
62%
They produce TGF-B
Development of Th1 cells is promoted by:
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6%
IL12
65%
IFN-y
6%
Large doses of antigen
24%
All of the above
Development of Th2 cells is promoted by:
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40%
IL-4
5%
Small doses of antigen
45%
Both of the above
10%
Neither of the above
Th2 cells are involved in:
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6%
Antigen processing
88%
Helping B-cells to respond to T-dependent antigen
6%
Mucosal immunity
0%
Secretion of IL-1
The primary role of Th2 cells is to
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6%
Function as T killer cells
6%
Activate NK cells
88%
Activate B cells
0%
Activate macrophages
All of the following statements about Th2 cells are true EXCEPT:
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17%
They produce IL-3, 4, 5 and 6
8%
Their development is inhibited by IFN-y
0%
Their development is promoted by IL-4
75%
They promote cell-mediated immunity