CD8 T-cells recognize the antigen in the form of
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86%
A peptide associated with MHC-class 1 mulecules
11%
A peptide associated with MHC-class II molecules
0%
A peptide associated with CD4 molecules
4%
A peptide associated with CD8 molecules
Regarding Th cells, all of the following statements are true EXCEPT
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4%
They activate macrophages
4%
They activate B cells
87%
They lyse target cells
4%
They recognize antigen presented by class II MHC molecules
One of the following is a professional antigen presenting cell
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4%
T cytotoxic cell
74%
B cell
4%
Naive T cell
4%
T helper cell
13%
NK cell
Which of the following is an antigen presenting cell?
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0%
Neutrophil
88%
Macrophage
4%
Eosinophil
4%
T lymphocytes
4%
NK cells
All the following are professional antigen presenting cells EXCEPT:
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4%
Macrophages
13%
B cells
0%
Dendritic cells
83%
NK cells
The role of the APC includes all of the following EXCEPT:
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11%
Processing of antigens
21%
Delivering the first signal to activate T cells
32%
Delivering the second signal to activate T cells
37%
Presenting non-self peptides associated with MHC II molecules to B cells
Dendritic cells (APC) are involved in:
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10%
Transporting the epitope to the surface of a B cell
15%
Suppressing the immune system
75%
Presenting peptides to naive cells
0%
Producing antibody
Vesicular pathogens are preserved:
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5%
With MHC I to CD4 Th cells
5%
With MHC I to CD8 Tc cells
0%
with MHC II to B cells
89%
With MHC II to CD4 Th cells
Vesicular peptides are generated from all of the following EXCEPT
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25%
Extracellular bacteria
19%
Intracellular bacteria
0%
Bacterial toxins
56%
Viruses living inside the cell
Extracellular bacteria are presented to T. cells in association with:
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12%
MHC class I
76%
MHC class Il
12%
Fc receptors
0%
C3b receptors
Peptides derived from a bacterial toxin are typically:
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6%
Presented on MHC I molecules to T helper cells
24%
Presented on MHC I molecules to T cytotoxic cells
65%
Present in the vesicular system
6%
Considered endogenous antigens
Which statement is INCORRECT?
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5%
MHC I molecule binds peptides and is recognized by TCR and CD8
16%
MHC II molecule binds peptides and is recognized by TCR and CD4
79%
Recognition of peptides carried on MHCII molecules on acell result in cytotoxic killing of that cell
0%
One cell may have both MHCI and MHC II molecules
Peptides arising in the vesicular system are presented to:
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6%
Cytotoxic T cells
88%
Helper T cells
6%
Both
0%
Neither
As regard peptides arising in the cytosol or in the vesicular system:
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75%
Cytosol peptides are carried on MHC I molecules
13%
Vesicular peptides are carried on MHC I molecules
6%
Cytosol peptides are presented to helper T cells
6%
Vesicular peptides are presented to cytotoxic T cells
The role of T cell in the immune response includes:
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88%
Recognition of epitopes presented with MHC molecules on cell surfaces
0%
Antigen presentation
0%
Phagocytosis
13%
Complement activation
During the process of antigen recognition, the second signal needed for T cell activation is delivered when:
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24%
CD40 ligand binds to CD40 molecule
6%
CD4 binds to MHCII molecule
6%
CD8 binds to MHCI molecule
65%
CD28 binds to B7 molecule
Which statement about the primary immune response is Not true
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13%
Requires two signals for activation Tealis
0%
Produces effector T cells
13%
Produces memory T cells
73%
Produces naive T cells
One of the following is a pro-inflammatory cytokine:
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14%
TGF - a
64%
TNF - ß
5%
IL 4
18%
IL 5
Th1 cells are characterized by:
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6%
They produce IL-4
6%
They are activated by IL-4
6%
Their development is promoted by IL-4
81%
Their development is inhibited by IL 4