2-year-old boy was brought to the emergency department because of fever, irritability, increased lethargy, and multiple episodes of diarrhea. The mother reported that she found her levothyroxine bottle empty a few hours earlier. Vital signs of the boy were blood pressure 130/80 mm Hg, heart rate 180 bpm, respirations 26/min. Laboratory test results on admission showed a total tri-iodothyronine level of 472 ng/dL (normal:
40-130 ng/dL). Which of the following drugs should be administered first to control hormone-related effects that could be rapidly lethal in this patient?
40-130 ng/dL). Which of the following drugs should be administered first to control hormone-related effects that could be rapidly lethal in this patient?
Q above
Anonymous Quiz
4%
Betamethasone
52%
Propranolol
9%
Potassium iodide
35%
Propylthiouracil
❤1
Which of the following is alpha-glucosidase inhibitor?
Anonymous Quiz
0%
Glimepiride
6%
Canagliflozin
0%
Pramlintide
94%
Acarbose
Which of the following drugs is most likely to cause hypoglycemia when used as monotherapy in the treatment of type 2 diabetes?
Anonymous Quiz
3%
Acarbose
63%
Glyburide
27%
Metformin
7%
Rosiglitazone
Which of the following insulin preparations can be given intravenously?
Anonymous Quiz
3%
Neutral Protamine Insulin
10%
Insulin glargine
83%
Regular soluble insulin
3%
Insulin detemir
A child with type 1 diabetes mellitus is on insulin. He is going to have surgery. Which of the following therapeutic regimens would you choose?
Anonymous Quiz
7%
Shift to a sulfonylurca
7%
Shift to metformin
83%
Keep using insulin
3%
Stop insulin for some time
53-year-old woman recently diagnosed with hyperthyroldism started an appropriate treatment. One month later, the following laboratory values were obtained: Red blood cell count (RBC): 4.6 × 10mm3 (normal 4.0-5.5 × 10°/mm3), White blood cell count (WBC): 0.6 × 103/mm.3 (normal 3.2-9,8 × 10%/mm3), Platelets 180 x 103/mm3 (normal
140-400 × 10%/mm*). Which of the following drugs most likely caused these results?
140-400 × 10%/mm*). Which of the following drugs most likely caused these results?
Q above
Anonymous Quiz
17%
Radioactive iodine
0%
Potassium iodide
78%
Methimazole
6%
Propranolol
Which of the following is a drawback of radioactive lodine therapy?
Anonymous Quiz
82%
Subsequent hypothyroidism in many patients
12%
Therapeutic effect is reversible by time.
6%
Rapid onset but short duration of action
0%
Difficulty in administration
The following is used in hypoglycemia coma if the patient could not take oral glucose:
Anonymous Quiz
7%
Liraglutide
0%
Canagliflozin
93%
Glucagon
0%
Sitagliptin
Which of the following oral antidiabetic agents are often assoclated with weight gain in type 2 diabetic patients?
Anonymous Quiz
28%
Metformin
22%
Glucosidase inhibitors
50%
Gliptins
🤔5
Insulin Lispro is:
Anonymous Quiz
89%
An ultra-short acting insulin analogue
4%
An intermediate acting insulin
7%
A premixed insulin
0%
A human recombinant insulin
Which of the following is an antidiabetic drug that enhances GLP-1 action and can be given orally?
Anonymous Quiz
3%
Pramlintide
31%
Liraglutide
55%
Sitagliptin
10%
Exenatide
A 33-year-old woman was admitted to the hospital because of anorexia, malaise, jaundice, and right upper quadrant abdominal pain for the past 2 days. The woman, who was 2 months' pregnant, was diagnosed with hyperthyroidism 1 month ago and started an appropriate therapy. Pertinent lab results on admission included alanine aminotransferase of 410 U/L (normal 20-40 U/L). Which of the following drugs most likely caused the patient's disorder?
Q above
Anonymous Quiz
32%
Methimazole
9%
Radioactive iodine
59%
Propylthiouracil
0%
Propranolol
Lactic acidosis is an adverse effect of which of the following?
Anonymous Quiz
78%
Biguanides.
15%
Sulfonylureas.
4%
Thiazolidinediones.
4%
Alpha-Glucosidase Inhibitors.
The thyroid inhibitor which produces the fastest response is...
Anonymous Quiz
55%
Lugol's iodine.
14%
Radioactive iodine
9%
Carbimazole..
23%
Methimazole
A 35 years old female patient with hyperthyroidism was prescribed carbimazole. After three weeks she called her doctor complaining of sore throat. She was advised to perform complete blood picture examination promptly. Which side effect is her doctor trying to discover?
Which of the following is a temporary Indication of Insulin after which the patient can go back to oral antidiabetic therapy?
Anonymous Quiz
14%
Diabetic ketoacidosis
77%
Undergoing a surgical operation
9%
Renal impairment
0%
Types 1 diabetes
Compared to sulfonylurea, which of the following characterizes repaglinide?
Anonymous Quiz
21%
No hepatic metabolism.
4%
Not an insulin secretagogue.
71%
Causes less sever hypoglycemia.
4%
Can be used in Type 1 diabetics with no insulin reserve