Regarding plasmids, which statement is True:
Anonymous Quiz
84%
They are extrachromosomal, double stranded DNA molecules
6%
They are much larger than the bacterial chromosome.
6%
They are non-replicating transferable DNA segments.
3%
They encode properties that are essential for bacterial growth
Which statement is CORRECT Concerning conjugative plasmids
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0%
Their copy number is above 30
3%
They are common in Gram-positive cocci
8%
They are usually small in size
90%
They carry the F factors.
Which of the following statements is true for oral anti-diabetic drugs?
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2%
Meglitinide is ineffective in regulating postprandial glucose
80%
Metformin could decrease absorption of vitamin B-12.
10%
Pioglitazone is harmless to the liver
7%
Acarbose can be used for diabetic patients suffering from gastrointestinal tract disturbances and fl
The mechanism of insulin secretion involves which of the following?
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12%
Opening of ATP-dependent potassium channels
68%
Increase in intracellular calcium
15%
Hyperpolarization of beta cells
6%
Block of sodium channels
One of the following anti-diabetics increases the insulin release via blocking ATP-sensitive K*-channel (K-ATP-Channels) of P -Cells of the pancreas:
Anonymous Quiz
3%
Biguanides
91%
Sulphonylurea
3%
Thiazolidinedionesd
3%
Alpha-Glucosidase Inhibitors
4) A female who has Type 2 diabetes mellitus is obese and wishes to lose weight. Which of the following medications would you advise her to use?
Anonymous Quiz
9%
Thyroxine supplements
82%
Liraglutide
6%
Sulfonylurea
3%
Prednisone5) Which of the
5) Which of the following is an adverse reaction to methimazole?
Anonymous Quiz
67%
Teratogenicity
7%
CNS toxicity
15%
Vomiting
11%
Renal toxicity
2-year-old boy was brought to the emergency department because of fever, irritability, increased lethargy, and multiple episodes of diarrhea. The mother reported that she found her levothyroxine bottle empty a few hours earlier. Vital signs of the boy were blood pressure 130/80 mm Hg, heart rate 180 bpm, respirations 26/min. Laboratory test results on admission showed a total tri-iodothyronine level of 472 ng/dL (normal:
40-130 ng/dL). Which of the following drugs should be administered first to control hormone-related effects that could be rapidly lethal in this patient?
40-130 ng/dL). Which of the following drugs should be administered first to control hormone-related effects that could be rapidly lethal in this patient?
Q above
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4%
Betamethasone
52%
Propranolol
9%
Potassium iodide
35%
Propylthiouracil
❤1
Which of the following is alpha-glucosidase inhibitor?
Anonymous Quiz
0%
Glimepiride
6%
Canagliflozin
0%
Pramlintide
94%
Acarbose
Which of the following drugs is most likely to cause hypoglycemia when used as monotherapy in the treatment of type 2 diabetes?
Anonymous Quiz
3%
Acarbose
63%
Glyburide
27%
Metformin
7%
Rosiglitazone
Which of the following insulin preparations can be given intravenously?
Anonymous Quiz
3%
Neutral Protamine Insulin
10%
Insulin glargine
83%
Regular soluble insulin
3%
Insulin detemir
A child with type 1 diabetes mellitus is on insulin. He is going to have surgery. Which of the following therapeutic regimens would you choose?
Anonymous Quiz
7%
Shift to a sulfonylurca
7%
Shift to metformin
83%
Keep using insulin
3%
Stop insulin for some time
53-year-old woman recently diagnosed with hyperthyroldism started an appropriate treatment. One month later, the following laboratory values were obtained: Red blood cell count (RBC): 4.6 × 10mm3 (normal 4.0-5.5 × 10°/mm3), White blood cell count (WBC): 0.6 × 103/mm.3 (normal 3.2-9,8 × 10%/mm3), Platelets 180 x 103/mm3 (normal
140-400 × 10%/mm*). Which of the following drugs most likely caused these results?
140-400 × 10%/mm*). Which of the following drugs most likely caused these results?
Q above
Anonymous Quiz
17%
Radioactive iodine
0%
Potassium iodide
78%
Methimazole
6%
Propranolol
Which of the following is a drawback of radioactive lodine therapy?
Anonymous Quiz
82%
Subsequent hypothyroidism in many patients
12%
Therapeutic effect is reversible by time.
6%
Rapid onset but short duration of action
0%
Difficulty in administration
The following is used in hypoglycemia coma if the patient could not take oral glucose:
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7%
Liraglutide
0%
Canagliflozin
93%
Glucagon
0%
Sitagliptin
Which of the following oral antidiabetic agents are often assoclated with weight gain in type 2 diabetic patients?
Anonymous Quiz
28%
Metformin
22%
Glucosidase inhibitors
50%
Gliptins
🤔5
Insulin Lispro is:
Anonymous Quiz
89%
An ultra-short acting insulin analogue
4%
An intermediate acting insulin
7%
A premixed insulin
0%
A human recombinant insulin
Which of the following is an antidiabetic drug that enhances GLP-1 action and can be given orally?
Anonymous Quiz
3%
Pramlintide
31%
Liraglutide
55%
Sitagliptin
10%
Exenatide