6. In mechanism of metaplasia, the following is true:
Anonymous Quiz
10%
a) A neoplastic process that maintain the integrity of the basement membrane
10%
b) Results from change in the phenotype of an already differentiated cell type
50%
c) Results from reprogamming of stem cells known to exist in normal tissue
30%
d) Can occur physiological or pathological
19) The major factors predisposing to thrombogenesis include all of the following except:
Anonymous Quiz
18%
a) Altered blood flow
0%
b) Endothelial injury
82%
c) Pattern of blood flow
0%
d) Hypercoagulability of blood
9) Which of the following statement regarding disseminated intravascular coagulation (DIC) is FALSE?
Anonymous Quiz
0%
a) Multiple thrombi develop in the microcirculation
0%
b) Rapid consumption of platelets, prothrombin & fibrinogen occurs
67%
c) Bleeding diathesis is solely due to thrombocytopenia
33%
d) Fibronogen degradation products (FDPs) increase due to rapid fibrinolysis.
44. A common site for hamartoma:
Anonymous Quiz
54%
a) Lung
15%
b) Duodenum
23%
c) Breast
8%
d) Urinary bladder
15. In acute inflammation, which is the correct sequence of events with regard to vascular flow and caliber?
Anonymous Quiz
10%
a) Vasodilation, margination, stasis, vasoconstriction
0%
b) Vasoconstriction, stasis, margination, vasodilation
90%
d) Vasoconstriction, vasodilation, stasis, margination
0%
e) Vasodilation, vasoconstriction, stasis, margination
0%
c) Vasodilation, stasis, vasoconstriction, marginaiton
13) Which of the following statements are TRUE?
Anonymous Quiz
9%
a)Amniotic fluid embolism occurs during labour due to tear in the placental membrane.
0%
b) Mortality rate of amniotic fluid embolism is high.
0%
c) Patients with amniotic fluid embolism develop acute pulmonary oedema, RDS & DIC.
91%
d) All of the above
4) Endothelial cells can be activated (develop procoagulant properties) by:
Anonymous Quiz
25%
a) Cytokines
8%
b) Hemodynamic factors
0%
c) Plasma constituents
67%
d) All of the above
46. Chemotatic factors may include the following except:
Anonymous Quiz
0%
a) Leukotriene B4
8%
b) Chemokine
92%
c) Nitric oxide
0%
d) Bacterial products
47. Which of the following is true about fibrin?
Anonymous Quiz
0%
a) Deposition of fibrin in inflammatory conditions is known as fibrosis
67%
b) Fibrin plays important functions in inflammation & repair
8%
c) Cellulitis is characterized by excess fibrin deposition
25%
d) All of the above
45. Which of the following is an effect of chemical mediators?
Anonymous Quiz
0%
a) Increased vascular permeability.
0%
b) Chemotaxis
0%
c) Fever
100%
d) All of the above
50. One of the following is associated with marked tissue necrosis:
Anonymous Quiz
0%
a) Silicosis
6%
b) Foreign body granuloma
6%
c) Sarcoidosis
88%
d) Tuberculosis.
3) Transudation may occur due to the following EXCEPT:
Anonymous Quiz
25%
a) Increased intravascular hydrostatic pressure.
50%
b) Increased intravascular oncotic pressure.
0%
c) Lymphatic obstruction
25%
d) Renal salt & water retention
58. Guardian of the genome is:
Anonymous Quiz
7%
a) RB gene
87%
b) P53 gene
0%
c) MYC gene
7%
d) Bcl2
22) The most reliable post mortem feature of left sided cardiac failure is:
Anonymous Quiz
8%
a) Systemic venous congestion
92%
b) Chronic venous congestion of lungs
0%
c) Enlargement of spleen and liver
0%
d) Oedematous ankles
50. Aflatoxins can cause:
Anonymous Quiz
0%
a) Lung carcinoma
14%
b) Mesothelioma
86%
c) Hepatic carcinoma
0%
d) Skin cancer
65. Immunohistochemistry is a powerful tool in diagnosing:
Anonymous Quiz
0%
a) High stage tumors
8%
b) Low grade tumors
69%
c) Poorly differentiated tumors
23%
d) Metastatic tumors
51. Bcl2 is considered:
Anonymous Quiz
0%
a) Proto-oncogene
7%
b) Oncogene
14%
c) Tumor suppressor gene
79%
d) Anti-apoptotic gene
53. Para-neoplastic syndromes commonly seen with:
Anonymous Quiz
54%
a) Lung carcinoma
31%
b) Hepatocellular carcinoma
15%
c) Breast carcinoma
0%
d) Colonic carcinoma
During acute inflammation, histamine-induced increased vascular permeability causes the formation of exudates (inflammatory edema)Which one of the listed cell types is the most likely source of the histamine that causes the increased vascular permeability
Anonymous Quiz
8%
a) Endothelial cells
0%
b) Fibroblasts
8%
c) Lymphocytes
83%
d) Mast cells
0%
e) Neutrophils
24) Caisson's discase is caused by:
Anonymous Quiz
0%
a) Amniotic fluid embolism
9%
b) Tumour embolism
18%
c) Hyper coagulability
73%
d) Air or gas embolism
53. Cells that engulf fibrin are:
Anonymous Quiz
0%
a) Neutrophils
0%
b) Eosinophils
100%
c) Macrophages
0%
d) Lymphocytes