Choose the incorrect statement about M2 receptors
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10%
Main site is the heart
12%
Present presynaptically on the cholinergic neurons
56%
They are Gs coupled
17%
They decrease intracellular cAMP
5%
Open k channels causing hyperpolarization
Atropine has the following pharmacological effects EXEPT:
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2%
a. Decreases gastric acid secretion
10%
b. Has a mydriatic effect
83%
c. Produces bronchoconstriction
5%
d. Increases the heart rate
Hyoscine differs from atropine in that it:
Anonymous Quiz
76%
a. Exerts depressant effects on the CNS at relatively low doses
5%
b. Contraindicated in thyrotoxicosis
11%
c. Is longer acting
8%
d. Has weaker antimotion sickness activity
Rivastigmine is anticholinesterase used in the treatmnet of
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3%
Glaucoma
92%
Alzheimer disease
5%
Bronchial asthma
0%
Myasthenia gravis
Atropine produces all the following actions on the eye except
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17%
Increase IOP
9%
passive mydriasis
3%
Cycloplegia
71%
Effect ends after 7 to 10 hrs
Hyoscine is preferred to atropine as pre-anasthetic medication in thyrotoxic patients because:
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3%
Hyoscine does not cause mydriasis
3%
Hyoscine does not decrease bronchial and salivary secretion
6%
Hyoscine does not stimulate RC
88%
Hyoscine does not cause tachycardia
0%
Hyoscine has no antiemetic action
Actions of Beta 1 receptor stimulation include :
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31%
Cardiac stimulation
3%
Increase in FFA in plasma
0%
Increase in sympathetic outflow from CNS
0%
Increase in serum renin
66%
All of the above
Cardiac B1 receptors induce the following actions except:
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7%
Positive inotropic action
0%
Positive chronotropic action
0%
Positive dromotropic action
90%
Reduction of cardiac work
3%
Increase in excitability
Stimulation of B2 receptors can induce which of the following actions?
Anonymous Quiz
11%
Bronchoconstriction
7%
Vc of coronaries and skeletal ms BV
14%
Reduction of aqeuous humor synthesis
0%
Contraction of detrusor ms
68%
Tocolytic action on pregnant uterus
Activation of B2 receptors in skeletal ms leads to the following actions except
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3%
Tremors
17%
Vasodilatation of BV supplying the skeletal ms
0%
Glycogenolysis anc increase in blood lactate
52%
Hyperkalemia
28%
All of the above
Alpha 1 adrenergic receptors have the following features except :
Anonymous Quiz
7%
Are Gq coupled
11%
Induce vc of blood vessels especially in skin and mucous membrane
11%
Cause contraction of urinary bladder sphincter
59%
Cause passive mydriasis
11%
Induce ejaculation of semen
Alpha 2 adrenoceptors are characterized by the following EXCEPT
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4%
Having an inhibitory effect on sympathetic outflow
4%
Reduce IOP by decreasing aqueous humor formation
79%
Stimulation of noradreanalin release from adrenergic neurons
13%
Inhibition of renin release from juxtaglomerular cells .
Application of Dipivefrine (lipophilic alpha 1 agonist) to the eye can result in :
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21%
A.Active mydriasis
0%
B.Passive mydriasis
17%
C.Decongistion of conjunctival blood vessels
4%
D.Miosis
58%
E.Both A and C
Application of beta antagonists to the eye can cause:
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9%
Miosis
4%
Cycloplegia
78%
Decrease in IOP
0%
Loss of light reflex
9%
Xerophthalmia
Systemic administration of phentolamine can lead to the following EXCEPT:
Anonymous Quiz
16%
Hypotension
8%
Relaxation of urinary bladder sphincter and trigone
20%
Loss of sweat secretion from palm and sole
48%
Bronchodilatation
8%
Failure of ejaculation in males
Local application of adrenalin to normal eye causes:
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20%
Active mydriasis
12%
Passive mydriasis
4%
Miosis
60%
Decongestion in cases of conjunctival congestion
4%
Xerophthalmia
Metabolic actions of adrenaline include all the following EXCEPT:
Anonymous Quiz
0%
High plasma renin level
0%
High plasma FFA level
4%
Calirogenic action
96%
Hypoglycemia
0%
High plasma lactate level
Which is the true statement about Atropine?
Anonymous Quiz
15%
Is derived of plant origin
0%
Is a tertiary amine
4%
Is not absorbed from intact skin
0%
Is a non selective competitive muscarinic antagonist.
81%
All of the above
Pharmacological actions of atropine include the following EXCEPT
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4%
Tachycardia
69%
Active mydriasis
12%
Antispasmodic
8%
Antiemetic
8%
Antiparkinsonian
Which of the following is not a CNS action of atropine?
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42%
Antiemetic in motion sickness
8%
RC stimulation
23%
CIC stimulation
27%
Inhibtion of tremors and rigidity in parkinsonism