ملاحظات د. زكية :
1- A. A. that enter the TCA cycle *through its intermediates* will be glucogenic, because they will end as OAA.
2- Acetyl CoA cannot synthesize glucose because its reaction is irreversible; and if it enters the TCA cycle, it will be oxidized to Co2 & H2O.
3- Trypsin has a central role in protein digestion because it also activates other proteolytic enzymes.
4- The difference between trypsin & carboxypeptidase B is that the latter is an "exopeptidase" acting on the terminal a. a. and releasing it, but trypsin is an endopeptidase.
5- Transamination reactions require PLP.
6- D A.A. deamination is not present in humans.
7- Fumarate is converted to malate in the cytosol by a cytosolic fumarase; then, it enters the TCA cycle. (or it can enter the mitochondria & be converted there... هكي قالت الدكتورة 🤷🏻♀)
8- There are 2 types of Carbamoyl Phosphate Synthetase: CPS-1 & CPS-2.
The one that participates in the urea cycle is: CPS-1
9- Pyruvate may be converted to OAA which in turn is used to synthesize glucose.
10- Alpha Ketobutyrate* DH needs the 5 Co-enzymes.
11- Methionine is synthesized by the body but in little amounts.
+ كلينيكال كوريليشنز مهمة.
1- A. A. that enter the TCA cycle *through its intermediates* will be glucogenic, because they will end as OAA.
2- Acetyl CoA cannot synthesize glucose because its reaction is irreversible; and if it enters the TCA cycle, it will be oxidized to Co2 & H2O.
3- Trypsin has a central role in protein digestion because it also activates other proteolytic enzymes.
4- The difference between trypsin & carboxypeptidase B is that the latter is an "exopeptidase" acting on the terminal a. a. and releasing it, but trypsin is an endopeptidase.
5- Transamination reactions require PLP.
6- D A.A. deamination is not present in humans.
7- Fumarate is converted to malate in the cytosol by a cytosolic fumarase; then, it enters the TCA cycle. (or it can enter the mitochondria & be converted there... هكي قالت الدكتورة 🤷🏻♀)
8- There are 2 types of Carbamoyl Phosphate Synthetase: CPS-1 & CPS-2.
The one that participates in the urea cycle is: CPS-1
9- Pyruvate may be converted to OAA which in turn is used to synthesize glucose.
10- Alpha Ketobutyrate* DH needs the 5 Co-enzymes.
11- Methionine is synthesized by the body but in little amounts.
+ كلينيكال كوريليشنز مهمة.
SoMA
ملاحظات د. زكية : 1- A. A. that enter the TCA cycle *through its intermediates* will be glucogenic, because they will end as OAA. 2- Acetyl CoA cannot synthesize glucose because its reaction is irreversible; and if it enters the TCA cycle, it will be oxidized…
زدت شوية ملاحظات أخرى لأن لقيت روحي ناسية صفحة.