Calculate the E-values or each o the ollowing, given that the number o milliliters o water shown will produce an isotonic solution rom 0.3 g o drug
substance.
(a) Apomorphine hydrochloride, 4.7 mL water
(b) Aminocaproic acid, 8.7 mL water
(c) Prilocaine hydrochloride, 7.7 mL water
(d) Procainamide hydrochloride, 7.3 mL water
(e) Gentamicin sul ate, 1.7 mL water

مهم جواب بالمصدر نقطه 31

Using the E-values in Table 11.1, calculate the number o milliliters o water
required to make an isotonic solution rom 0.3 g o each o the ollowing:
(a) Antipyrine
(b) Chlorobutanol
(c) Ephedrine sul ate
(d) Silver nitrate
(e) Zinc sul ate

مهم جواب نقطه 30 بالمصدر

H ow many milligrams o sodium chloride may be used in the preparation o
15 mL o an eye drop containing 1% tropicamide and 0.5% chlorobutanol to
render the solution isotonic with tears?
(a) 18 mg
(b) 31.5 mg
(c) 103.5 mgصح هذا جواب
(d) 135 mg

Determine i the ollowing commercial products are hypotonic, isotonic, or
hypertonic:
(a) An ophthalmic solution containing 40 mg/mL o cromolyn sodium and
0.01% o benzalkonium chloride in puri ied water.
(b) A parenteral in usion containing 20% (w/v) o mannitol.
(c) A 500-mL large volume parenteral containing D5W (5% w/v o anhydrous
dextrose in sterile water or injection).

مهم جدا هذا سوال جواب نقطه 27 بالمصدر

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