Remember:
-Asthma, postnasal drip, and reflux disease are the three most common causes of chronic cough in a nonsmoker not taking angiotensin-converting enzyme (ACE) inhibitors. All ACE inhibitors, including lisinopril, can cause chronic cough, possibly due to altered bradykinin metabolism.
#Respiratory
-Asthma, postnasal drip, and reflux disease are the three most common causes of chronic cough in a nonsmoker not taking angiotensin-converting enzyme (ACE) inhibitors. All ACE inhibitors, including lisinopril, can cause chronic cough, possibly due to altered bradykinin metabolism.
#Respiratory
Heart failure
classes
HFrEF <40%
HFpEF >50%
HFiEF <40% then >40%
HFmREF between 40 and 50
HFhEF >60%
Treatment
4 pillars within 1 month
1-BB. First line (Metoprolol 12.5-25-200mg once,
carvidolol 3.125_25mg twice ,
Bisoprolol (concor) 1.25_ 10mg once) up titrated every 2 weeks
>30% improvements in mortality
2- ACEI/ARBs
Ramipril 1.25- 10 mg once daily
begin with BB at same time
Novel drug...
ARNI (Sacopatril 49 + Valsartan51)
100-200mg twice
Expensive used mainly in HFrEF
3-MRA
Spironolactone 25-50mg once after 1-2 weeks
if the patient develop gynacomastia change to eplerenon with same dosage
4-Empa (empagliflozine , canagliflozine , dapagliflozine)with 10mg once. No titration needed
Na glucose cotransport inhibitor
Used for all stage
the only drugs that improve prognosis in HFmrEF
Dr / Salah Al-Shawki
#Cardiology
classes
HFrEF <40%
HFpEF >50%
HFiEF <40% then >40%
HFmREF between 40 and 50
HFhEF >60%
Treatment
4 pillars within 1 month
1-BB. First line (Metoprolol 12.5-25-200mg once,
carvidolol 3.125_25mg twice ,
Bisoprolol (concor) 1.25_ 10mg once) up titrated every 2 weeks
>30% improvements in mortality
2- ACEI/ARBs
Ramipril 1.25- 10 mg once daily
begin with BB at same time
Novel drug...
ARNI (Sacopatril 49 + Valsartan51)
100-200mg twice
Expensive used mainly in HFrEF
3-MRA
Spironolactone 25-50mg once after 1-2 weeks
if the patient develop gynacomastia change to eplerenon with same dosage
4-Empa (empagliflozine , canagliflozine , dapagliflozine)with 10mg once. No titration needed
Na glucose cotransport inhibitor
Used for all stage
the only drugs that improve prognosis in HFmrEF
Dr / Salah Al-Shawki
#Cardiology
Berlin criteria for ARDS
•Acute onset: respiratory failure within one week of a known predisposing factor (e.g., sepsis, pneumonia) or worsening respiratory symptoms
Bilateral opacities (on chest x-ray or CT)
Hypoxemia: PaO2/FiO2 ≤ 300 mm Hg
Respiratory failure cannot be fully accounted for by heart failure or fluid overload.
#Respiratory
•Acute onset: respiratory failure within one week of a known predisposing factor (e.g., sepsis, pneumonia) or worsening respiratory symptoms
Bilateral opacities (on chest x-ray or CT)
Hypoxemia: PaO2/FiO2 ≤ 300 mm Hg
Respiratory failure cannot be fully accounted for by heart failure or fluid overload.
#Respiratory