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Antinuclear Antibody +ve:
4 S


-SLE
-Systemic sclerosis
-Sjorgen syndrome
-Sometimes normal

#Medicine
Difficult intubation:

L E M O N


-Look externally
-Evaluate 3-3-2 rule
-Mallampati score
-Obstruction
-Neck Mobility.


#Medicine
Varicose vein : symptoms

AEIOU

-Aching
-Eczema
-Itching
-Oedema
-Ulceration (LDS, hemosiderin, varicosities)

#Medicine
Causes of chronic constipation


πŸ‡ΊπŸ‡ΈπŸ‘€JOE BIDEN πŸ›


πŸ—³Juvenile eating disorder(anorexia nervosa)
πŸ—³Other(pregnancy, systemic sclerosis, myotonic dystrophy)
πŸ—³Environmental and dietary(low fiber diet, immobility,...)

πŸ—³Bowel obstructing lesions
πŸ—³Irritable bowel syndrome, Idiopathic chronic constipation
πŸ—³Drugs(Aluminum,Opiates,
...), Dyssynergic defecation
πŸ—³Endocrine and metabolic (hypothyroidism,hypokalemia,hypercalcemia)
πŸ—³Neurogenic disorders(Multiple sclerosis, Hirschsprung disease,...)


#Medicine
β€’Carpal tunnel syndrome; causes


πŸ‡ΊπŸ‡ΈDONALD TRUMPπŸ›

πŸ’²Diabetes
πŸ’²Overuse injury, Obesity
πŸ’²Neoplasm
πŸ’²Acromegaly
πŸ’²Low thyroid(hypothyroidism)
πŸ’²Dialysis-related amyloidosis

πŸ’²Trauma(colles fx)
πŸ’²Rheumatiod arthritis
πŸ’²Use of Aromatase inhibitors
πŸ’²Menopause, Myxoedema
πŸ’²Pregnancy


#Medicine
#Surgery
Hypercalcemia DDx

πŸ₯›HyperCALCEMIAS


πŸ’ Hyperparathyroidism
πŸ’ Carcinoma
πŸ’ Antacids containing Calcium, Acute renal failure
πŸ’ Lymphoma, Leukemia, Low phosphate, Lithium
πŸ’ Calcium Supplements, Congenital (familial hypocalciuric hypercalcemia)
πŸ’ Endocrine: hyperthyroidism, pheochromocytoma
πŸ’ Multiple Myeloma, Metistatic Lesions to Bone, Milk-alkali syndrome
πŸ’ Immobilization (exacerbates another underlying disorder), Iatrogenic(thiazide, diuretics, vitamin D)
πŸ’ Addison's Disease, Acromegaly, A hypervitaminosis
πŸ’ Sarcoid and other granulomatous diseases


#Medicine
Thyroid storm
Causes and management

🏷Causes

πŸŒͺTHIS Powerful storm

πŸ”»Trauma
πŸ”»Hyperthyroidism
πŸ”»Infection/ Illness/ Iodine load
πŸ”»Surgery
πŸ”»Parturition

🏷Management

4πŸ…Ώβ€™s

πŸ…Ώredinisone
πŸ…Ώropylthiouracil
πŸ…Ώropranolol
πŸ…Ώotassium Iodide


#Thyroid
#Surgery
β€’What are the causes of anemia in hypothyroidism?

-Causes of anemia:
1)Anemia of chronic disorder
2)Iron deficiency
3)Vitamin B12 deficiency
4)Folate deficiency
5)Other factors responsible menorrhagia in female, anorexia.

#Medicine
#Surgery
β€’What are the types of anemia in hypothyroidism?

-Anemia may be:
1-Usually normocytic normochromic
2-Iron deficiency, if menorrhagia (in female)
3-May be macrocytic due to associated pernicious anemia (due to deficiency of vitamin B12).

#Thyroid
#Surgery
β€’Why thyroxine should be started in low dose?

-Because if high dose is given, it may precipitate anginal attack.

#Thyroid
β€’What is the bedside test in hypothyroidism?

-Ankle jerk, which shows slow relaxation, also called β€œhung-up reflex” (other jerks may also show slow relaxation).

β€’How slow relaxation is best elicited in the ankle? Why slow relaxation?

-It is best elicited in kneel down position on a chair or bedside.
-Slow relaxation is due to decreased rate of muscle contraction and relaxation.

#Thyroid
β€’Cave!!

-If the patient has deficiency of cortisol (as in hypopituitarism or Addison’s disease), corticosteroid should be given first and then thyroxine. Otherwise, if thyroxine is given first without correcting cortisol deficiency, there will be severe Addisonian crisis.

#Thyroid
#Medicine
β€’What is Hashimoto’s thyroiditis?

-It is an autoimmune thyroiditis characterized by destructive lymphoid infiltration of thyroid leading to atrophic change with regeneration and goiter formation.
-It is more common in middle aged woman.

-The goiter is usually diffuse, moderately enlarged and firm or rubbery. Sometimes, it may be soft to hard.

-Antithyroid antibody (very high, >1000 IU/L)β€”antimicrosomal (antiperoxidase) in 90% and antithyroglobulin antibodies (no rise of TSH-receptor antibody).

-Initially, the patient may present with features of toxicosis, called Hashi-toxicosis.

-About 25% patients are hypothyroid at presentation. In the remaining patients, serum T4 is normal and TSH is normal or raised.
-There is risk of developing overt hypothyroidism in future.

-Treatment– thyroxine (it reduces the size of goiter also).

#Thyroid
#Medicine
#Surgery
β€’What is the natural history of Graves’ disease?

-It may be hyperthyroid, euthyroid followed by hypothyroidism.

β€’What is euthyroid Graves’ disease?

-The patient is clinically and biochemically euthyroid, but there is ophthalmopathy (also there is diffuse goiter, dermopathy).
-Thyroid releasing hormone (TRH) stimulation test show flat response curve.

#Thyroid
#Surgery
#Medicine
β€’What is thyrotoxic crisis?

-Thyrotoxic crisis is a medical emergency that's characterized by life threatening increase of signs and symptoms of thyrotoxicosis (also called thyroid storm).

β€’What are the Precipitating factors for thyroid crisis?

1-Infection
2-Stress
3-Surgery in unprepared patient
4-Following radioiodine therapy (due to radiation thyroiditis).

#Thyroid
#Medicine
β€’What are the Features of thyrotoxic crisis?

-High fever
-Restlessness,agitation and irritability
-Nausea, vomiting, diarrhea and abdominal pain
-Tachycardia, AF and in elderly, cardiac failure
-Confusion, delirium and coma.

β€’Diagnosis:
-Mostly clinical and high degree of suspicion is vital.
-FT3, FT4 and TSH should be done immediately.

#Thyroid
#Medicine
β€’Treatment of Thyrotoxic crisis

(Blood sample is taken for T3, T4 and TSH).
1-The patient should be treated in intensive care unit (ICU).

2-Propranolol 80 mg 6 hourly (or 1 to 5 mg IV 6 hourly).

2-IV fluid (normal saline and glucose).

3-Carbimazole 40 to 60 mg daily. Or propylthiouracil 150 mg 6 hourly (if needed, through Ryle’s tube). Carbimazole can be given per rectally also.

β€’Other therapy:
-Sodium ipodate, a radiographical contrast media, 500 mg daily is rapidly effective. Or potassium iodide or Lugol’s iodine may be given.
-Dexamethasone 2 mg 6 hourly and amiodarone are also effective.
-Broad spectrum antibiotic.

β€’General measures:
-Control of temperature and O2 therapy.
-After 10 to 14 days, the patient can usually be maintained on carbimazole alone.

Mortality rate in thyrotoxic crisis is 10%.

#Thyroid
#Medicine
β€’HELLP SYNDROME

-Hemolysis
-Elevated Liver enzymes
-Low platelets.

#Obs_Gyne
β€’Cirrhosis Complications:

VARICES

Varices
Ascites/Anemia
Renal failure (hepatorenal syndrome)
Infection
Coagulopathy
Encephalopathy
Sepsis.

#Liver
#Medicine
Radiological features of Rheumatoid Arthritis:

(LESS):

L: Loss of joint space
E: Erosions
S: Soft tissue swelling
S: Soft bones (osteopenia).

#Rheumatology
#Medicine
β€’Falciparum Malaria complications:

CHAPLIN

-Cerebral malaria/ Coma
-Hypoglycemia
-Anemia
-Pulmonary edema
-Lactic acidosis
-Infections
-Necrosis of renal tubules.

#Infections
#Medicine