Quick Notes
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•Intralesional Triamcinolone Uses:
(Dose is usually 3-5 mg /ml)

- Inflammatory Cysts & Nodules of acne.
- Alopecia areata.
- Keloids & Hypertrophic scars.
- Small Thick psoriatic plaques.
- Cutaneous Sarcoidosis.
- Lichen planus.
- Prurigo nodularis.
- Hydradenitis suppurativa.
- Dyshydrotic Eczema.
- Granuloma annulare.
-Lichen simplex chronicus.
-Recurrent localized Bullous pemphigoid
-Scabietic Nodules.

#Dermatology
Telangiectasia can be seen in:

1-Systemic sclerosis "CREST syndrome".
2-SLE.
3-Dermatomyositis.
4-Rosacea.
5-BCC.
6-Habitual corticosteroid use.
7-Alcoholism.
8-Pregnancy.
9-Hereditary.
10-Chronic exposure to the sun or extreme temperatures.

#Dermatology
Rifaximin:

-It is a broad-spectrum, nonabsorbable oral antibiotic.
-Reduces the number of ammonia-producing intestinal bacteria.
-May be added to lactulose if a second episode occurs to prevent recurrent episodes of hepatic encephalopathy.

زمان كانوا يستخدموا Neomycin.

#Medicine
Antinuclear Antibody +ve:
4 S


-SLE
-Systemic sclerosis
-Sjorgen syndrome
-Sometimes normal

#Medicine
Difficult intubation:

L E M O N


-Look externally
-Evaluate 3-3-2 rule
-Mallampati score
-Obstruction
-Neck Mobility.


#Medicine
Varicose vein : symptoms

AEIOU

-Aching
-Eczema
-Itching
-Oedema
-Ulceration (LDS, hemosiderin, varicosities)

#Medicine
Causes of chronic constipation


🇺🇸👤JOE BIDEN 🏛


🗳Juvenile eating disorder(anorexia nervosa)
🗳Other(pregnancy, systemic sclerosis, myotonic dystrophy)
🗳Environmental and dietary(low fiber diet, immobility,...)

🗳Bowel obstructing lesions
🗳Irritable bowel syndrome, Idiopathic chronic constipation
🗳Drugs(Aluminum,Opiates,
...), Dyssynergic defecation
🗳Endocrine and metabolic (hypothyroidism,hypokalemia,hypercalcemia)
🗳Neurogenic disorders(Multiple sclerosis, Hirschsprung disease,...)


#Medicine
Carpal tunnel syndrome; causes


🇺🇸DONALD TRUMP🏛

💲Diabetes
💲Overuse injury, Obesity
💲Neoplasm
💲Acromegaly
💲Low thyroid(hypothyroidism)
💲Dialysis-related amyloidosis

💲Trauma(colles fx)
💲Rheumatiod arthritis
💲Use of Aromatase inhibitors
💲Menopause, Myxoedema
💲Pregnancy


#Medicine
#Surgery
Hypercalcemia DDx

🥛HyperCALCEMIAS


💠Hyperparathyroidism
💠Carcinoma
💠Antacids containing Calcium, Acute renal failure
💠Lymphoma, Leukemia, Low phosphate, Lithium
💠Calcium Supplements, Congenital (familial hypocalciuric hypercalcemia)
💠Endocrine: hyperthyroidism, pheochromocytoma
💠Multiple Myeloma, Metistatic Lesions to Bone, Milk-alkali syndrome
💠Immobilization (exacerbates another underlying disorder), Iatrogenic(thiazide, diuretics, vitamin D)
💠Addison's Disease, Acromegaly, A hypervitaminosis
💠Sarcoid and other granulomatous diseases


#Medicine
Thyroid storm
Causes and management

🏷Causes

🌪THIS Powerful storm

🔻Trauma
🔻Hyperthyroidism
🔻Infection/ Illness/ Iodine load
🔻Surgery
🔻Parturition

🏷Management

4🅿’s

🅿redinisone
🅿ropylthiouracil
🅿ropranolol
🅿otassium Iodide


#Thyroid
#Surgery
What are the causes of anemia in hypothyroidism?

-Causes of anemia:
1)Anemia of chronic disorder
2)Iron deficiency
3)Vitamin B12 deficiency
4)Folate deficiency
5)Other factors responsible menorrhagia in female, anorexia.

#Medicine
#Surgery
What are the types of anemia in hypothyroidism?

-Anemia may be:
1-Usually normocytic normochromic
2-Iron deficiency, if menorrhagia (in female)
3-May be macrocytic due to associated pernicious anemia (due to deficiency of vitamin B12).

#Thyroid
#Surgery
Why thyroxine should be started in low dose?

-Because if high dose is given, it may precipitate anginal attack.

#Thyroid
What is the bedside test in hypothyroidism?

-Ankle jerk, which shows slow relaxation, also called “hung-up reflex” (other jerks may also show slow relaxation).

How slow relaxation is best elicited in the ankle? Why slow relaxation?

-It is best elicited in kneel down position on a chair or bedside.
-Slow relaxation is due to decreased rate of muscle contraction and relaxation.

#Thyroid
Cave!!

-If the patient has deficiency of cortisol (as in hypopituitarism or Addison’s disease), corticosteroid should be given first and then thyroxine. Otherwise, if thyroxine is given first without correcting cortisol deficiency, there will be severe Addisonian crisis.

#Thyroid
#Medicine
What is Hashimoto’s thyroiditis?

-It is an autoimmune thyroiditis characterized by destructive lymphoid infiltration of thyroid leading to atrophic change with regeneration and goiter formation.
-It is more common in middle aged woman.

-The goiter is usually diffuse, moderately enlarged and firm or rubbery. Sometimes, it may be soft to hard.

-Antithyroid antibody (very high, >1000 IU/L)—antimicrosomal (antiperoxidase) in 90% and antithyroglobulin antibodies (no rise of TSH-receptor antibody).

-Initially, the patient may present with features of toxicosis, called Hashi-toxicosis.

-About 25% patients are hypothyroid at presentation. In the remaining patients, serum T4 is normal and TSH is normal or raised.
-There is risk of developing overt hypothyroidism in future.

-Treatment– thyroxine (it reduces the size of goiter also).

#Thyroid
#Medicine
#Surgery
What is the natural history of Graves’ disease?

-It may be hyperthyroid, euthyroid followed by hypothyroidism.

What is euthyroid Graves’ disease?

-The patient is clinically and biochemically euthyroid, but there is ophthalmopathy (also there is diffuse goiter, dermopathy).
-Thyroid releasing hormone (TRH) stimulation test show flat response curve.

#Thyroid
#Surgery
#Medicine
What is thyrotoxic crisis?

-Thyrotoxic crisis is a medical emergency that's characterized by life threatening increase of signs and symptoms of thyrotoxicosis (also called thyroid storm).

What are the Precipitating factors for thyroid crisis?

1-Infection
2-Stress
3-Surgery in unprepared patient
4-Following radioiodine therapy (due to radiation thyroiditis).

#Thyroid
#Medicine
What are the Features of thyrotoxic crisis?

-High fever
-Restlessness,agitation and irritability
-Nausea, vomiting, diarrhea and abdominal pain
-Tachycardia, AF and in elderly, cardiac failure
-Confusion, delirium and coma.

Diagnosis:
-Mostly clinical and high degree of suspicion is vital.
-FT3, FT4 and TSH should be done immediately.

#Thyroid
#Medicine
Treatment of Thyrotoxic crisis

(Blood sample is taken for T3, T4 and TSH).
1-The patient should be treated in intensive care unit (ICU).

2-Propranolol 80 mg 6 hourly (or 1 to 5 mg IV 6 hourly).

2-IV fluid (normal saline and glucose).

3-Carbimazole 40 to 60 mg daily. Or propylthiouracil 150 mg 6 hourly (if needed, through Ryle’s tube). Carbimazole can be given per rectally also.

•Other therapy:
-Sodium ipodate, a radiographical contrast media, 500 mg daily is rapidly effective. Or potassium iodide or Lugol’s iodine may be given.
-Dexamethasone 2 mg 6 hourly and amiodarone are also effective.
-Broad spectrum antibiotic.

General measures:
-Control of temperature and O2 therapy.
-After 10 to 14 days, the patient can usually be maintained on carbimazole alone.

Mortality rate in thyrotoxic crisis is 10%.

#Thyroid
#Medicine
HELLP SYNDROME

-Hemolysis
-Elevated Liver enzymes
-Low platelets.

#Obs_Gyne