•Precancerous lesions of Gastric Cancer:

1•H. pylori infection, chronic gastritis
2•Pernicious anaemia
3•Intestinal metaplasia
4•Adenomatous polyps more than 2 cm
5•Agammaglobulinaemia
6•Benign gastric ulcer
7•Previous gastric surgery
8•Stomach remnant (stump carcinoma)
9•Menetrier’s disease.
10•Benign gastric ulcer.

#Surgery
#Medicine

DUODENAL BLOW-OUT 5%:

-It is a very serious complication of Billroth II gastrectomy, occurs usually on 4–5th day after surgery.

#Surgery
#Stomach

DUMPING SYNDROME(Post-cibal Syndrome):

-It is common in females, seen after Billroth II surgery.

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#Stomach

•EARLY DUMPING SYNDROME:

-It is common and more severe type Incidence is 10% Vasomotor symptoms appear immediately after food, lasts for 30-40 minutes, aggravated by bulky food.
-It is relieved by lying down, aggravated by more food.

-Clinical features: Sweating, tachycardia, colicky pain and diarrhoea, Hypotension and features of hypovolaemia.

#Surgery
#Stomach

•LATE DUMPING SYNDROME:

-It is of less severe type Incidence is 5% It usually occurs 2 hours after meal.
-It is relieved by glucose and aggravated by exercise.

-Pathogenesis: Due to initial hyperglycaemia insulin secretion is stimulated which in turn leads to hypoglycaemia.

-Clinical features: Tremor, fainting, nausea, Features of hypoglycaemia.

-Treatment: Symptoms are less severe and so treated conservatively, by giving glucose and food.

#Surgery
#Stomach

•Mackler triad (esp. in Boerhaave syndrome) in Esophageal Perforation:

1-Vomiting and/or retching
2-Severe retrosternal pain that often radiates to the back
3-Subcutaneous or mediastinal emphysema:
crepitus in the suprasternal notch and neck region or crunching/crackling sound on chest auscultation (Hamman sign).

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•Extra-esophageal symptoms (respiratory )of GERD:

1-Reflux-induced Asthma.
2-Chronic Cough.
3-Aspiration pneumonia.
4-Recurrent laryngitis.
5-Pulmonary fibrosis.
6-Hiccups.
7-Pharyngeal & laryngeal irritation horsiness of voice.
8-Otitis media.

#Medicine

•Complications of Barrett’s oesophagus:

1-Ulcerations and stricture
2-Dysphagia
3-Bleeding
4-Perforation
5-Adenocarcinoma of O-G junction (25 times more common).

#Surgery

•In Esophageal Carcinoma:

-It is 6th most common cancer in the world.
-It is less than 1% of all cancers.
-It is 7% of all GI malignancies.
-Common in:
Middle third—50%.
Lower third—33%.
Upper third—17%.

-Recent onset of dysphagia is the commonest feature.

#Surgery
#GIT

•Helicobacter pylori infection, which can cause stomach cancer, has not been associated with esophageal cancer.

#Surgery

•Whipple's triad

-Typical presentation of insulinomas.
Consists of :

1-Symptomatic fasting hypoglycemia.

2-Plasma glucose less than 50 mg/dl during the attack .

3-Dramatic improvement after administration of glucose.

#Medicine
#Endocrine

•Hour glass contracture:
-It is a complication of gastric ulcer, occurs exclusively in women, is due to cicatricial contracture of lesser curve ulcer.

•Tea-pot deformity (Hand-bag stomach):
-It is a complication of GU, it's due to cicatrisation and shortening of the lesser curvature.

#Surgery
#Stomach

-Acute ulcers after major burns are called as Curling’s ulcers.

-Acute ulcers after cerebral trauma or neurosurgeries are called as Cushing’s ulcers.

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#Stomach

•Types of gastric ulcer (Daintree Johnson):

Type I 👉🏼 In the antrum, near the lesser curve,55٪.

Type II 👉🏼 Combined gastric ulcer (in the body) with duodenal ulcer, 25٪.

Type III👉🏼Prepyloric ulcer, 15٪.

Type IV👉🏼Gastric ulcer in the proximal stomach or cardia, 5٪.

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#Stomach

-Carcinoma in proximal stomach is common in young and upper socioeconomic group.

-Carcinoma in distal stomach is common in old and lower socioeconomic groups.

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#Stomach

-Carcinoma stomach is the commonest cause of Krukenberg’s tumour.

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#Stomach

Remember:


-GRRD 👉🏼 Adenocarcinoma
-Achalasia 👉🏼 SCC.

#Esophagus

Early vs Advanced gastric cancer.

#Surgery

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